In orthodontics, low level laser therapy (LLLT) has also been used as a modality to enhance the bone remodeling and accelerate the tooth movement. LLLT increases the levels of Rreceptor activator of nuclear factor kappa-B ligand (RANKL) in periodontal ligament. RANKL is a proliferation marker which binds to osteoclasts lineage and proliferate them, hence increases the rate of orthodontic tooth movement (Kapila, Lancero, and Johnson 1998). Aihara et al. cultured rats preosteoclast like cells and found increase in the levels of RANKL after laser application (Aihara, Yamaguchi, and Kasai 2006). Similarly few more In vitro studies have reported the same effects of LLLT on cultured osteoclasts via expression of MMP-9, cathepsin K, and α (v) β3 …show more content…
2009). In vivo human studies have also shown the biostimulatory effects of LLLT on orthodontic tooth movement (table 4). Cruz applied 780 nm diode laser to investigate the amount of tooth movement and found significant acceleration after application of 50J/cm2 (Cruz et al. 2004). The same wavelength of laser and energy input was used by Sousa who also reported significant increase in velocity of tooth movement (da Silva Sousa et al. 2011). However Limpanichkul and Heravi found LLLT ineffective in producing significant difference in velocity of orthodontic tooth movement pertaining to the use of higher energy density (21.4 J) by Heravi and very low energy input described by Limpanichkul; as the most effective range of LLLT for biomodulation is reported to be 0.5-4 J/cm2 (Mester, Mester, and Mester 1985; Limpanichkul et al. 2006; Heravi, Moradi, and Ahrari). Genc investigated acceleration along with the levels of nitric oxide in gingival crevicular fluid (GCF) after application of LLLT. He also found increase in velocity of tooth movement, while there was no significant changes in the level of nitric oxide reported (Genc et al. 2013). Doshi Mehta used lower energy input, which was found effective in acceleration of canine retraction simultaneously reducing the pain associated with the
Having succeeded in the pursuit of my DMD as one of the top students in my class both clinically and didactically, my immediate goal was to broaden my horizons in understanding dental medicine. This understanding encompassed the multifaceted and dynamic collaboration of specialties- both of which share the goal of comprehending biomechanics concerning maxillofacial complexion and the proper treatment of various malfunctions.
Michael Longaker’s interests lie at the intersection of wound/bone regeneration and stem cell biology. In the Peripheral Blood-Derived Mesenchymal Stem Cells: Candidate Cells Responsible for Healing Critical-Sized Calvarial Bone Defects, the efficacy of peripheral blood (PB) for use in regenerative medicine is significant, with its retrieval viewed as relatively easy. Experiments such as bone regeneration were carried out with the use of PB stem cells. The paper finds that through a specific coculturing process mesenchymal cells can be derived from PB (CD34+) which happen to be choice candidates for quicker bone healing and re-calcification in bone defects (Li). The key discoveries here are the identification of easily retrievable source of stem cells, which help give rise, under a specific culturing protocol, to a specific group of non-hematopoietic cells. This is directly in line with Dr. Longaker’s research as he investigates the possible uses of regenerative medicine in skeletal regeneration. Here we are provided an example of how these CD45- cells can be utilized for treatment of bone defects as it facilitations bone formation and osteogenesis. What should be asked here is how viable is this form of treatment. There is a lot of discussion surrounding the necessary conditions to produce these BD-MSCs and how it is very condition dependent. It would have been preferable to know the amount of time and the amount of cells required to see efficient
Argenis FerrebusMr. RottenbergCOMP 200031 January 2018Writing ExerciseLocating a Community ArtifactArtifact: Air-Driven High-Speed Dental HandpieceDescription and AnalysisAssumptions/Existing KnowledgeI am familiar the air-driven dental handpiece to some extent. I have seen it every time I have gone to the dental office. I have had this artifact used on me but I’ve never used it myself. Every time an air-driven handpiece is used on me, I feel a very uncomfortable sensation in my tooth. This artifact reminds me of a drill and is also known as a dental drill. Dentist uses this “drill” in order to remove cavities, tooth decay, and plaques. I personally believe the people who invented the air-driven dental handpiece created it in order to remove
This Paper analyzes the Case 16: Medical Laser Equipment. Some of the given facts are as follows:
Laser therapy has been postulated as an alternative or adjunctive treatment to periodontal therapy. The bactericidal and detoxifying effects of the diode laser during non-surgical periodontal treatment have been documented. Also for patients with aggressive periodontitis (AgP), the use of a diode laser with scaling and root planning (SRP) has shown a superior effect over SRP or the laser alone for certain parameters. Moritz et al concluded a significant reduction in the amount of bacteria and inflammation using a diode laser in combination with SRP. However controversy remains concerning the efficacy of diode laser therapy during periodontal treatment. The results of some studies did not demonstrate effectiveness of the combination of laser and SRP therapy over SRP alone in terms of microbiologic and gingival inflammation parameters.
I decided to use oraqix because the patient had a few pockets depths between 6-7 mm, and was very sensitive during the power instrumentation. It helped me to effectively remove the plaque and the calculus from the pockets with the hand instruments, but I found that it was not as effective when I used the Cavitron. After the removal of plaque and calculus I reviewed OHI with my patient Evelyn and reinforced the proper use of dental floss and have the patient practice in her mouth. During the afternoon section, I worked on the mandibular arch and as before I started with the power instrumentation. However, I was not able to use it in all the mandibular teeth because some of them had recession, and the patient was extra-sensitive. The good thing was the mandibular arch had only one area with 6-7 mm of pocket depth. I also used Oraqix in this area, but did not help with the recession because the pain was related to the pulp and not to the gingiva, in where Oraqix works. After finishing with debridement, my patient expressed having pain on the distal surface of tooth # 17. We decided to take a PA of the area because that part of the tooth was not visible in the HBW I
Misuse of copyright is when the copyright holder misuses the legally-backed rights in order to extend its dominance regarding the use of the copyright work to an extent which may not be acceptable when kept in perspective with law and equity.
Consequently, I was involved in the mechanical testing of bioceramic endodontic materials with regards to their physical properties and hydration behavior. Also, I am participating in an ongoing Micro-CT study to evaluate the quality of root filling using different filling techniques and sealers.
Zheng, Z., Kang, H., Lee, S., Kang, S., et al. (2014). Up-regulation of fibroblast growth factor (FGF) 9 expression and FGF-WNT/β-catenin signaling in laser-induced wound healing. Wound repair and regeneration. 22(5): 660-665.
We choose to take the technological road when it comes to procedures like fillings, gum disease treatment, and gum reshaping. That’s because we wholeheartedly believe that using a laser to perform these treatments is the most effective for you. By using lasers, we are more accurate during the procedure, and the recovery time has proven to be quicker. You’ll be confident in your smile after having a filling, gum disease treatment, or gum reshaping procedure at Fox Family Dentistry!
The force to the teeth is minimal. This means that the treatment offers an optimal level of
The laser vaporizes tissue it comes into contact with or cuts tissue, and it is strengthens the bond between a tooth and its filling when used during the curing process. It also boosts the tooth whitening process, acting as a heat source during this procedure," Dr. Daoud continues.
From extractions to root canals, Leidenheimer Dental Group can perform a wide variety of dental procedures with the help of the latest technology. They employ the use of laser technology to make routine
Osteoblasts differentiation is induced by several extracellular signaling factors which include; fibroblast growth factors, parathyroid hormone-related protein, bone morphogenic proteins (BMPs), transforming growth factor, Wnts and members of the growth hormone/IGF family. These numerous signaling factors activate a wide verity of intracellular mechanisms implicated in osteoblast differentiation such as SMADs, protein Kinases, MAPK, and beta-catenin. In addition two transcription factors, Runx2 and osterix (Osx) are known to regulate the commitment of pre-osteoblast cells into the osteogenic lineage.169, 274 It is only recently that NF-κB signaling has been added to the list of transcription factors capable of regulating osteoblast differentiation and function. This is mainly because expression of inflammatory cytokines on sites of inflammation inhibits bone formation. In contrast to osteoblast, osteoclast differentiation is driven primarily by a single cytokine, RANKL, which regulates the expression of NFATc1 and c-Fos. These two genes are the primary transcription factors responsible for osteoclast differentiation. In osteoclast, RANKL signals macrophages to differentiate into osteoclasts through induction of NF-κB and NFATc1. Both the canonical and non-canonical NF-κB activations are stimulated by RANKL157. NF-κB activation is crucial for osteoclast differentiation
Daily, children and adults all over the world flood into orthodontic offices for consultations, routine management checkups, and the rest. The majority of people in today’s age have had or will have braces at some point in their life. However, most people may not be aware of the downsides to appliances such as braces. Although advancements in orthodontic technology have made braces faster and more efficient, they are causing unnecessary stress on ligaments and gene tissue found inside the mouth because of the new found techniques to speed up tooth movement.