Lung Cancer : The Leading Cause Of Death

What are lung cancers? Lung cancers are the abnormal cells which grow in uncontrolled manner in one or both lungs. They do not function as normal lung cells and do not develop into healthy lung tissue. The abnormal cells can grow, form tumours and interfere with the normal functions of the lung (Lungcancer.org, 2015). Lung cancers can be divided into two major types, namely non-small cell lung cancers (NSCLC) and small cell lung cancers (SCLC). NSCLC can be further classified into three main subtypes, namely adenocarcinoma, squamous-cell carcinoma and large-cell carcinoma (Longo & Harrison, 2012). Lung cancers can be diagnosed by chest X-ray, computerised tomography (CT) scan, positron emission tomography-computerised tomography (PET-CT) scan, bronchoscopy and biopsy (Nhs.uk, 2015). Unfortunately, lung cancers are often diagnosed at the later stages. This is due to the unrecognisable symptoms and warning signs at the earlier stages. NSCLC are often diagnosed at stage IV which accounts for 30-40% of cases whereas 60% of SCLC is diagnosed at stage IV. Lung cancer usually originates from the cells lining the bronchi, bronchioles and alveoli. Carcinogens especially tobacco smoke will alter the gene expression of the normal human lung cells, resulting in cell mutation. The proto-oncogenes will be converted to mutated form, oncogenes. Mutation leads to the decreased expression of the tumour suppressor genes. This results in uncontrolled cell proliferation, cell

Lung Cancer is a disease which consists of uncontrolled cell growth in lung tissues. Lung cancer consists of two types, Non-small cell lung cancer, and small cell lung cancer. (NSCLC) is the most common type of lung cancer. The bronchi are the large air tubes leading from the trachea to the lungs that convey air to and from the lungs, and where most lung cancers begin. The body normally maintains cell growth only

Lung cancer can be caused by multiple factors and many factors can work together to cause someone to have lung cancer. Besides smoking, radon, secondhand smoke, the environment and someone’s occupation can all cause lung cancer. As we already know smoking is the number one cause of lung cancer cases worldwide and over forty-three million people just in the United States smoke cigarettes. There are more than fifty chemicals in tobacco smoke that are ingested each time someone smokes. Some of these chemicals include benzene (which can be found in pesticides and gasoline), Formaldehyde (which preserve dead bodies), pesticides (which are found on lawns and gardens) and Tobacco-specific N-nitrosamines (Martin, 2012). When a person inhales the chemicals in cigarettes, they inhale thousands of poisons, toxic metals, and

Although many people have heard about lung cancer, they don't know that there are two major types of lung cancer. The types of lung cancer are non-small cell lung cancer (NSCLC) and small cell lung cancer (SCLC). NSCLC breaks down into three different types and approximately makes up 85-90% of the cancers that patients are diagnosed with. The first type of NSCLC is adenocarcinoma. This type of cancer is usually found in smokers however it is the most common lung cancer found in nonsmokers. This cancer typically attacks younger adults and targets women. This cancer tends to develop on the outside layers of the lungs and it can be found before it spreads throughout the body. The second type of NSCLC is squamous cell carcinoma. This cancer is linked to smoking and forms in the inner airways of

According to a paper published by the Center for Diseases and Control, Lung Cancer has the highest mortality rate in the US than any other cancer type. In 2011, about 156,953 people died from the disease as about 207,000 cases of ailing lung cancer patients were diagnosed that year. This number is set to see an increase over the years if adequate care in research is not given .Song described Lung cancer, as Non-Small Cell Lung Cancer (NSCLC) and Small Cell Lung Cancer (SCLC) with the former being responsible for about 85% of diagnosis cases and deaths reported each year. The most common types of NSCLC include adenocarcinomas, large cell carcinomas, and squamous cell carcinomas and as expected, most of these NSCLC types are related to smoking. However, adenocarcinomas have been found in patients who never smoked. Common but inadequate ways of NSCLC treatment include surgery, radiation therapy , and chemotherapy (Witschi , 2001) but the most effective form of NSCLC treatment has been known to be targeted therapies (Nguyen et al. , 2011) . This research invention has taken cancer treatment to another level because of the specificity of the drug inhibitors used to target carcinomas, or protein kinases that involve in pathways of the cancer. Adequate research has led to efficient modifications to use of targeted-therapies for specific fusion genes that code for oncogenes and kinesin genes i.e the Kinesin Family 5B gene and the RET (Rearranged during Transcription). Song also

Lung cancer is a type of cancer is found in men and women lung cancer have something to do with your lungs. Your lungs which help pump oxygen into your body and also release carbon out of your body which helps you live because you need oxygen. Lung cancer is a common cancer in ages 60 and up it can also be found in any age but is most commonly in 60 year olds and older. Lung cancer is the leading cause of cancer deaths in the U.S. in both men and women. Lung cancer is also one of the most preventable kinds of cancer, but smoking is mainly the leading cause of lung cancer.

Over decades, lung cancer globally continues to be the leading killer in both genders. In the United States, smoking is responsible for 90% lung cancer deaths in men and about 80% in women. About 15 decades ago, lung cancer was not considered as the leading killer because it was an extremely rare disease about 1% in total of cancer cases. However, by the year 1927, the percentage increased into 14%. During World War I, many soldiers and civilians started smoking to release stress. Eventually, that made the lung cancer rate and smoking addiction in the population started to increase. In a research that published in 2001, lung cancer annually kills over one million people worldwide (Witschi, 2001). The death rate, which caused by lung cancer,

There are two types of Primary lung cancer called small cell and non-small cell. Small cell cancer looks a lot like oats, which is why it used to be called oat cell cancer. Small cell lung cancer is most common among smokers. It is a very quick spreading cancer and it is responsible for 25% of all lung cancers. The other 75% of lung cancer is non-small cell lung cancer, which is the most common form. However, non-small cell lung cancer is far less fast spreading than the small cell cancer.

Lung cancer is a deadly class of disease that is specifically composed of uncontrolled cell growth in the pulmonary extremities of the body (Crosta. 2009). When left untreated, the abnormal lung tissue eventually develops into life-threatening tumors (Crosta, 2009). Lung cancer is a disease that is particularly caused by smoking, nonetheless there are cases where it is simply developed naturally. The disease can severely harm the health of an individual over the course of years. In addition, researchers have determined that lung cancer is the leading cause of cancer deaths among both men and women (Mayo Clinic Staff, 2014). As of today, about 210,828 people in the United States have been diagnosed with lung cancer (CDC, 2015). In 2012, about

According to the US Department of Health and Services, More than 380,000 12-to-13-year-olds and almost four million 14-to-17-year-olds have smoked cigarettes at least once (Johnston, 2014, p.1). He also explained that the numbers of smokers between cigarettes, hookahs. E-cigarettes are increasing in the past few years between adults and teenagers (Johnston, 2014, p.3). I'm also concerned because my dad and my three brothers smoke more than 2 packs of cigarettes a day. Now let's discuss the causes of lung cancer.

The cells of non-small cell lung cancer are larger than the cells of small cell lung cancer. Most (about 7 of every 8) people diagnosed with lung cancer have non-small cell lung cancer. It doesn’t grow and spread as fast as small cell lung cancer, and it’s treated differently. Non-small cell lung cancer is a group of lung cancers that are named for the kinds of cells found in the cancer and how the cells look under a microscope. The three main types of non-small cell lung cancer are squamous

Non-small cell lung cancer accounts for approximately 85-90% of lung cancer. Non-small cell lung cancer (NSCLC) is divided into three different groups. While these cancer cells vary in shape, size, and chemical-makeup, they are all grouped into NSCLC because of similar treatment and outlook. (American Cancer

Lung cancer is a very common malignant disease around the world, which is mainly caused by long-term exposure to tobacco smoke (85% of all cases). [1] It is reported by WHO that, globally in 2012, 1.8 million people suffered from lung cancer, and 1.6 million patients died of lung cancer. [2] In cancer-related death all around the world, lung cancer ranks the top in men and second in women, only after breast cancer. [3] Statistically, 17.4% of lung cancer patients in the United States only have five-year survival after the diagnosis, and the average survival rate is even worse in the developing countries. [4]

Lung cancer is the second most commonly diagnosed cancer in both men and women with an estimated 222,500 new cases expected to be diagnosed in 2017, and an estimated 155,870 deaths, more than any other cancer site (1). A minority of lung cancers (only 16%) are diagnosed at a localized stage which is the only window of disease that is potentially curable with surgery (2). Nonetheless, 5-year survival ranges between 30-50% for lung cancers diagnosed at stage I or II, thus despite early detection and curative resection, a significant proportion of patients will die from recurrent disease within 5 years (1, 2).

Cancer is one of the serious health problems affecting the world among which lung cancer is an important one. The mortality rate due to lung cancer is very high. But the early detection of lung cancer can reduce the mortality rate. Studies shows that $85 $ of the lung cancer in males and $75$ lung cancer in females are due to cigarette smoking [1].