MATERIAL AND METHODS
This prospective randomized controlled clinical trial was conducted from September 2012 to November 2013 and included patients who underwent microincision cataract surgery (MICS) at the Hospital Virgen de los Lirios. The study recruited 60 eyes of 41 patients. Eligible patients were those aged 65 to 80 with senile cataract and no other concomitant disease that would prevent a postoperative best corrected visual acuity (BCVA) of 20/40 or better. Exclusion criteria included history of ocular surgery or trauma, corneal disease, glaucoma, uveitis, vitreous opacities, retinopathy or visual pathway defects. Other exclusion criteria were current treatment with systemic steroids, immunosuppressants, anticoagulants or prostaglandin analogue eye drops. Patients with intraoperative complications or extended surgical time were also excluded.
After informed consent was obtained, participants with history of allergy to penicillin were assigned to the vancomycin group (Group 1). An equal number of patients were selected at random and assigned to the control group (Group 2). Information gathered from patients included date of birth, sex, history of drug allergy and systemic diseases, medication use and surgeon. Patients in Group 1 received an intracameral injection of vancomycin (1 mg in 0.1 ml), whereas those in Group 2 received an intracameral injection of cefuroxime (1 mg in 0.1 ml). Vancomycin injection was prepared from the commercially available vancomycin
Dr. Gumma mentioned that in prescribing antibiotic, it is very important to determine the patient’s allergy to
The patient is allergic to Penicillin; this antibiotic is part of the penicillin family. This is drug is not to be taken if allergic to any penicillin antibiotic.
5158–66). However, post-operatively Mr. Smith is currently prescribed Amoxicillin & Clavulanic acid 875mg/125 mg this is a penicillin antibiotic used to treat a range of different infections, in Mr. Smith’s case this is to reduce the possibility of postoperative infection (MIMS Online 2016). Common signs effects of this medication include diarrhoea, muscle or back pain, nausea and vomiting (Australian Medicines Handbook 2017c). Prior to beginning therapy, it is important to be aware if the patient has had a history of an allergic reaction to beta-lactams such as cephalosporins or penicillin’s as severe adverse effects could occur (MIMS Online 2016).
A Studies done at MNH and MC found high SSI (Akoko et al., 2012)(Mawalla, Mshana, Chalya, Imirzalioglu, & Mahalu, 2011).This is contrary to another study at KCMC which showed low SSI rate(Kitembo & Chugulu, 2013)
Amelie’s presenting style, along with the printed syllabus has fast-forwarded my knowledge and confidence level with prescribing antibiotics. Amelie begins by reviewing gram positive bugs. Amazingly, I never noticed that the three gram positives were Staph, Strep, and Enterococcus and that all others were gram negative. I have tried to memorize all the gram negatives. By taking this approach, Amelie, as she describes, has allowed more room in my brain for other information (Advanced Practice Education Associates, 2015). Amelie explained the beta-lactam ring and allergies with any penicillin or cephalosporin beautifully. The diagram of the “pink pentagon” and “blue box” clearly explained why most people can take a cephalosporin if they have had a reaction to penicillin and why some cannot (Advanced Practice Education Associates,
The guidelines of the European Glaucoma Society (EGS) for the management of glaucoma due to corticosteroid treatment are; (1) discontinuation of corticosteroid therapy or switch to weaker steroid (2) administration of topical or systemic IOP lowering medications (3) laser trabeculoplasty and (4) glaucoma surgery in intractable cases. These recommendations are, however, not specific for intravitreal administration of
Client reported she is having side effect of her eye surgery, both eyes are inflames and next upcoming and next scheduled appointment at Bellevue Hospital is scheduled for 8/31/2015 but she will be going to the Emergency Room tomorrow. She uses the following medications: Sodium Chlorides 5% eye oint ( apply to both eyes at bed times), Prednisolone AC 1% eye drop ( Instill one drop into each eye 4 times a day), Pred Forte 1ml and Vigamox 0.5% as base.
It works by inhibiting bacterial protein synthesis (8). Because of this resistance, clindamycin is usually only used in penicillin allergic patients. No interactions that would reduce efficacy of clindamycin or other medications exist (5).
In Cleveland Clinic, trained pharmacists could monitor patients’ labs and adjust medication dosages based on the lab under the consent. One of the medications was antibiotics, especially vancomycin. The center tried to expand the existed service to home care setting. Therefore, my preceptor and I were talking with the person in the legislative field.
Post-cataract endophthalmitis is a rare but serious complication.1 Recent studies show a rate of postoperative endophthalmitis after cataract surgery of 0.04% to 0.29%.2-4 However, it remains the most important concern for surgeons, because it can have devastating consequences on vision.5 It is recently reported that 9% of patients with endophthalmitis have a poor ocular prognosis (visual acuity <20/100).6
The critical values for the drug level are an abnormal value which higher or lower than therapeutic values. These values can cause drug toxicity to patients and required immediate attention from physicians. Critical values are always reported by telephone which the problems and obstacles are unknown action and utilization. The data of critical values reporting in 2005 showed that vancomycin hasd been reported the most. The purpose of this pilot study is to determine the rate of use of the critical values reporting system and to identify the incidence of false positive critical values of vancomycin level.
The most frequently reason for prescription of antibiotics was abscesses, 170/464 (37%). The most widely used NSAIDs were Par¬acetamol (Acetaminophen), resulting in 270/464 responses (58.2%). The most commonly prescribed antibioticswas Amoxicillin (n = 344, 74.1%). Only 4.4(8.8%) of the participants followed the WHO guide for good prescription. Female students showed significantly more errors than their male counterparts regarding the dose and drug’s brand name; p=0.002,p= 0.030, respectively. There was a significant reduction in prescription errors with the increase of the students’ educational level (p=0.001), and students from public universities showed more errors in knowing brand names and duration of treatment comparing to those from private universities
The clinical pharmacist here at Monongahela Valley Hospital focused on Vancomycin dosing for the patients in the hospital. The pharmacist looked at the patient’s vancomycin troughs and renal function to determine if they are given the correct dose or if any dose changes needs to be made based on the status of the patient. When I got to make the IV bags for the patients, I got to use what I learned in school for practice. I am a hands-on learner, so I enjoyed making the IV and compounding medications. Most of the time that I was here at the hospital I was gathering medications to be delivered to the patients; this task I was very comfortable at doing because of my experience in retail
Endophthalmitis is a vision-threatening complication that commonly occurs after cataract surgery. Visual outcomes are often debilitating, with 50% recovering 20/40 vision and about 30% being able to count their fingers.1 Because cataract surgery is the most commonly performed ocular procedure worldwide, postoperative endophthalmitis is an important public health issue associated with significant morbidity and high medical costs. Current prevention strategies in the United States include routine operating room aseptic protocols and perioperative topical antibiotic prophylaxis.2 However, recent studies of the past decade favor intracameral antibiotic administration, which involves a bolus injection into the anterior chamber at the end of surgery,
Ethical challenges are the most profound when dealing with patient safety; compliance with the prophylaxis antibiotic administration guidelines is paramount to a surgical patient in order to decrease the possibility of a post operative surgical site infection. Antibiotic timing requires