Major Depressive Disorder ( Mdd )

1857 Words May 6th, 2015 8 Pages
INTRODUCTION

Major depressive disorder (MDD) is one of the most common mental illnesses around the world. It is estimated that over 120 million people suffer from depression and it can be recognised in people as having episodes of low mood and a loss of interest in activities. MDD is a very disabling mental illness and highly costly in society. It is also referred to as clinical depression and it affects how you feel, think and behave. As a result it can lead to various emotional and physical problems (Cowen, Sharp, & Lau, 2013).
Internationally major depression is recognised in many different parts of the world and is diagnosed via the DSM-IV diagnostic criteria which takes into consideration a range of somatic symptoms. The relapse rate in people with major depression is high. Half of those who experience one depressive episode will experience another even after treatment. Therefore, discovering effective treatments in major depression is important especially in people who have been treatment resistant (Mintz, 2012).
Most people with depression feel better with medication. However, this is not always the case. There are many biochemical theories as to why depression may arise in a person. Therefore, the aim of this assignment will be to focus on two biochemical theories behind major depression in conjunction with the latest research. The first theory will look at how serotonin also known as 5-HT has an impact on major depression. In the second biochemical theory, the…
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