Malaria is a recognizable disease around the globe. While significant efforts have been made since antimalarial treatments were introduced in the 1940s, the disease continues as an endemic world-wide. Ongoing efforts by global public health leaders and scientists continue to track disease patterns, causes, and effects on health outcomes to continuously work toward protecting and saving lives. Although current prevention efforts such as insecticide-treated bed nets (ITNs) and indoor residual spraying (IRS) have impacted the rates of malaria, other advances are being made to control and eradicate malaria. Novel interventions such as spatial targeting for predicting risk in endemic geographic regions, using microbes to eliminate mosquito …show more content…
Cause of Disease
Malaria is caused by a parasite (e.g., Plasmodium) that infects the female anopheles mosquito, which in turn feeds on humans as the host. Individuals are infected with the Plasmodium parasite via vector-borne transmission, but malaria can also be transmitted through blood transfusions, mother to unborn child (e.g. vertical transmission), or as a result of sharing needles contaminated with the blood from an infected individual. The symptoms of malaria can vary, with the most common being fever, malaise, weakness, gastrointestinal complaints (e.g., nausea, vomiting, and diarrhea), neurologic complaints, headaches, chills, cough, back pain, and myalgia (Centers for Disease Control and Prevention, 2013). Malaria can be serious or even fatal to a person who is infected. Identification and treatment of malaria needs to be done rapidly through laboratory testing and treatment with the use of antimalarial medications.
Influence of Agent
The agent in malaria is one of a pervasive parasite - Plasmodium sporozoites. The sporozoites collect in the salivary ducts of the female anopheles mosquito and are then transmitted to the next host (Kappe, Buscaglia, & Nussenzweig, 2004). Transmission of sporozoites through salivation of the female anopheles mosquito is unrecognizable, which makes it to be such a difficult disease to control. Plasmodium sporozoites attach to the salivary glands by different micronemal proteins that
It is caused by a parasite that infects certain mosquitos that feed on humans. People infected with malaria usually suffer from high fevers, shaking chills, achy muscles, headaches, tiredness, and flu-like illness. It may also cause jaundice and anemia. The malaria parasite is found in the red blood cells of a person which means it can be transmitted through blood transfusions, organ transplants, or the shared use of needles syringes contaminated with blood. Malaria is not contagious; it cannot be transmitted from one person to another. Some parasites can remain dormant in the infected person’s body for up to four years after they are bitten. When the parasite comes out of hibernation and begins to invade the red blood cells, the person will become sick.
There have been many attempts at preventing malaria, none of which have been very successful. These have usually involved protecting human beings from mosquitoes, the dreaded carriers
Malaria (also called biduoterian fever, blackwater fever, falciparum malaria, plasmodium, Quartan malaria, and tertian malaria) is one of the most infectious and most common diseases in the world. This serious, sometimes-fatal disease is caused by a parasite that is carried by a certain species of mosquito called the Anopheles. It claims more lives every year than any other transmissible disease except tuberculosis. Every year, five hundred million adults and children (around nine percent of the world’s population) contract the disease and of these, one hundred million people die. Children are more susceptible to the disease than adults, and in Africa, where ninety percent of the world’s cases occur and where eighty percent of the cases
Malaria is a life threatening disease that has the capability of impacting the lives of about 3.2 billion people around the world. This large amount of people accounts for almost half of the world 's population. In the United States alone, there are about 1,500 cases of malaria every year. Although Malaria is preventable, and even curable, many countries do not have the money and resources to fight this disease. 1As of 2015, there are 97 countries and territories that are known to have ongoing cases of malaria transmission and there were 214
blood cells. The heparin sulfate has been suggested to be an important receptor for the IT4(var60) expressed by the parasite, once the red blood cell is infected (Angeletti et al., 2015). Using the ITvar60 rosetting variant the study’s objective to establish if binding to receptors occur through the use of a common structurally conserved binding site. The exact mechanism of binding remains unknown, however evidence narrowed down possible ways of neutralizing the infected red blood cells. The possibilities of controlling the infected red blood cells could be executed by directly blocking the binding site, through antibodies, or inducting a conformational change in the target protein once it is bound. Although Plasmodium falciparum is known
According to the health and environment, Malaria is a universal contagious disease and also a tremendous social complication all around the world, especially in South Asia, and Africa. Approximately, 3 billion of the community are in danger of infection in 109 regions. Every year, there is a prediction of 250 million compacts of miasm prominent to 1 million annihilations, particularly adolescents under 5 years old. The structure that causes the greatest unhealthy form of paludism is a imperceptible parasite that is known as the “Plasmodium falciparum”.
Malaria is caused by a parasite that is transferred by a bite of an infected female Anopheles mosquito. The most deadly form of malaria is known as Plasmodium falciparum because almost all deaths from malaria are caused by strain. In addition to this, falciparum
Malaria kills approximately five hundred thousand people per year. Ninety percent of those deaths occur in the Saharan section of Africa. Although Approximate 3 billion people live in areas where they are at risk of contracting malaria in a total of 106 countries around the world. “There were an estimated 198 million malaria cases worldwide in 2013, mostly pregnant women and children”. (Unknown author, malarianomore.org, 2015) “There are about 10,000 malaria cases per year in Western Europe, and 1300-1500 in the united stated and ….In Saharan, Africa maternal malaria is associated with up to 200,000 estimated infant deaths yearly.” (Wikipedia, obtained 2015)
About 3.3 billion people, that is about half of the world’s population are at risk of contracting malaria (figure 1). Every year there are 250 million cases of malaria, and nearly 1 million deaths. That amounts to 2,732 deaths per day. Out of those million people that die every year, 800,000 of them are African children under the age of 5. To control malaria three actions need to be taken: insecticides need to be used to decrease the vector population, people have to be educated as to how to prevent the vector from reproducing, and anti-malarial drugs need to be distributed. To understand the vector and what the vector is, scientists had to first discover what the parasite was and how it worked. It was not until the year 1880 that French Physician Charles Laveran discovered that Malaria was caused by a protozoan in the genus Plasmodium (Malaria, 2013)
Malaria is a serious infectious disease and sometimes fatal. A parasite known as a protozoan, which is a single celled microorganism that lives within the host is the cause for this potentially deadly disease. In this case, the host is a mosquito. “There are 430 various genus Anopheles (mosquito) species, but only 30-40 species carry the malaria parasite. There are many other species of mosquito’s that do not carry the malaria parasite, approximately 3,500 types in all.” They are broken up into 41 different classes such as the Culex Tarsalis that causes West Nile Virus and many more. Malaria is not contagious in the normal sense of the word. You cannot catch it by sneezing or coughing on someone. Anyone who has the disease will find Malaria in the RBC. The most common mosquito bites that carry the malaria virus are the Plasmodium Falciparum and Plasmodium Vivax, which usually bite from dusk to dawn. The most severe and deadliest malaria is from the Plasmodium Falciparum of the genus anopheles species, found in Africa and New Guinea.
Malaria is a growing problem around the world. This disease has taken the life of thousands of people. Malaria is a mosquito-borne disease caused by a protozoan parasite. The protozoan parasite belongs to the family Plasmodium. Anopheles mosquitoes act as a vector for the disease. This means the mosquito will harbor the disease then transfer that disease to a host, such as a human (Krajana et al., 2014). This protozoan Plasmodium protozoan requires two different hosts. It requires a vertebrate intermediate host such as a human and an insect host, also known as a vector which in this case is the
Malaria is a tropical disease which is prevalent in countries across the equator, particularly in sub-Saharan Africa. It is spread by Anopheles mosquitoes (infected with plasmodium), which bite the host and inject the malaria parasite (plasmodium) into the blood of the host. [1] After this the parasite travels to the liver where it reproduces. Then it re-enters the bloodstream and reproduces and multiplies inside the red blood cells, as a result of this the infected red blood cells burst, releasing parasites into the blood. The infected red blood cells burst within two to three days of being infected, this causes fevers, fatigue and headaches. The symptoms of malaria can range from diarrhoea and sweating to muscle pains, anaemia due to the loss of red blood cells and even death.
The economic and non- economic effects of malaria is so dire that the international community cannot ignore it anymore. There is the need for adequate research and funding into the study and proper understanding of the disease so that the proper steps can be taken to completely
Malaria affects hundreds of millions of people per year, and in 2013, caused an estimated 584,000 deaths, the highest burden of which occurred in Africa (World Health Organization, 2014a). It is a vector borne illness that is transmitted to humans by being bitten by malaria carrying female anopheles mosquito (World Health Organization, 2014b). Of the approximately half of one million people who die each year of malaria, 78 % of these are children under the age of five, placing them as one of the highest risk groups for malaria (World Health Organization, 2014a). It is essential that the recognition and treatment of a child with malaria happen quickly and efficiently because children have a high risk of rapid disease progression, which if
Malaria is one of the diseases that has caused deaths to many people, more so those living in prone localities. As a result, there is the need for weighty research to be done about Malaria so that better control methods can be mitigated. Even though some works have been done in the study of malaria that has informed the current treatment methods, there is still need for more analysis to help in the regular updates. Therefore, the insights provided hitherto and henceforth are crucial in the understanding and update of effective management and control of malaria. In addition, this gives awareness on the best way of handling a microorganism of clinical importance and determines the causative agents of various diseases to understand how to manage them. It is important to help the individual student to gain skills on how to receiver bacteria from the body of a human being. It places an individual student at the better position to acquire familiarity with the laboratory and clinical practices that help in carrying out the routine identification of bacteria in the samples collected.