Mammalian And Chick Model Similarities

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The molecular mechanisms underlying avian lung development are being increasingly more explored. Nonetheless, they are still less studied than mammalian ones. The chick model is a suitable and appealing animal model for research since it circumvents major ethical issues, it is affordable, with shorter gestation times and more easily maintained/manipulated than mammalian models. Despite the major structural morphological differences, when compared to mouse/rat adult lung, early avian pulmonary development presents several molecular similarities. On the other hand, molecular differences may account for the specifics of the avian tubular lung. Nevertheless, further studies are still needed to dissect and to unveil mechanisms responsible for the
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