Mediated Gene Regulation For Cancer Therapy Essay

An abnormality in this process leads to a number of problems, including cancer. MicroRNAs are a type of RNA which inhibit the expression of genes and play a vital role in the development of cancer. Of notable interest is miR-378, as it increases tumor angiogenesis and growth and also enhances the survival of these cells, by decreasing the expression of tumor suppression genes like Sufu. A study testing human cell lines found that when Sufu expression levels were high, miR-378 expression levels were low, and when Sufu levels were low, miR-378 levels were high, showcasing that the two were negatively correlated. Because repression of Sufu can lead to rampant proliferation of cells, the inhibition of Sufu is essential in order for miR-378 to promote angiogenesis and increase cell

Ovarian cancer is a lethal gynecological malignancy; although median age of diagnosis is 56 and older (post-menopausal) it can affect women of any child-birthing age. It is the 5th most common cancer diagnosed in the UK with 7,284 new cases in 2013 (Ovarian Cancer Statistics, 2013) Although the incidence is less than that of breast cancer, there is a greater number of deaths (4,271 deaths) associated with it. Almost three-quarters of the ovarian cancer are diagnosed at late stages after tumors have metastasized within the peritoneal cavity.

Ovarian cancer is cancer that begins in the ovaries. Ovaries are reproductive glands establish only in women. The ovaries produce eggs (ova) for reproduction. The eggs journey during the fallopian tubes into the uterus where the fertilized egg embeds and establish into a fetus. The ovaries are also the major cause of the female hormones estrogen and progesterone. One ovary is situated on each side of the uterus in the pelvis. Many types of tumors can generate rising in the ovaries. The majority of these are benign (noncancerous) and never multiply outside the ovary. Benign tumors can be treated effectively by removing either the ovary or the part of the ovary that contains the tumor. Ovarian tumors that are not benign or malignant (cancerous)

Ovarian cancer is cancer of the ovaries and is listed as the fifth cause of death in women. Ovaries are the reproductive glands of only females and the main source of a female’s estrogen and progesterone. The ovaries are made up of 3 kinds of cells, which can also develop different types of tumors. Epithelial tumors start from the cell that covers the outer surface of the ovaries. Germ cell tumors start from the cells that produce the eggs. Stromal tumors start from the structural tissues that hold the ovary together and produce the female hormones (1).

Scientists have long been studying ovarian cancer and potential therapies. This includes understanding how the tumor is able to survive despite our best efforts. It's

Ovarian cancer is less common, with a projected 22, 440 new cases. However, it carries a much higher mortality rate.

Ovarian cancer is a disease in which malignant or cancerous cells are found in the ovaries. The ovaries are two small organs that are located on each side of the uterus. The way cancer develops is when cells begin to grow out of control. Cancer cells are different from normal cells because they continue to grow and instead of dying, they create abnormal cells that form into a tumor. Woman around age 35-74, ovarian cancer is the fifth leading cause of death. The earlier this cancer is treated the better. Most woman don’t have symptom and when they do end up finding out that they have ovarian cancer their already on their 3rd or higher stage. Every woman diagnosed with this cancer has a survival rate of 30.6% (NOC, 2016).

Endometrial and Ovarian Cancer are two of a fatal diseases that occur among woman. Infect Ovarian cancer is more fatal than endometrial cancer and accounts for almost half of the gynecologic cancer mortality in the world. Therefore there needs to be a careful analysis of the contributing factors which increase the risk of these diseases.

Ovarian cancer is the fifth most common cancer in women in the UK. Overall the United Kingdom’s survival rates are low, with diagnosed women surviving for more than 5 years (less than 35%). Even though the survival rates still remain low, they have still progressed in recent decades, principally due to new treatments and enhancements (Rooth, C, 2013).

The cervical cancer is considered as the most common type cancers in women not only in the United States, but also around

Based on the data 22,000 women are diagnosed with ovarian cancer every year .If diagnosed early the 5 year survival rate is said to be 93% .Here we do an analysis to find out the best optimal path of care for a person , from the insurance company’s perspective.

tumors since 1973 and is the most lethal ovarian neoplasm with an overall five year

The word cancer is scary. All cancers take their toll but ovarian cancer by itself is very deadly among cancers in women. The ovarian cancer is a silent killer because the symptoms are often vague ones like, gaseousness indigestion/bloating sensation or a frequent need to pass urine so a patient often presents in an advanced stage to the doctor.

Ovarian cancer is the rapid and unregulated division of the ovarian cells and is referred to as the ‘most lethal gynaecologic cancer’ (1). Despite a small lifelong risk of only 1.3% in the general population and only a small proportion of 1.3% of all new cancers, ovarian cancer is the fifth-leading cause of cancer-related death in women (2). This essay will give an insight into the development of this type of cancer, the symptoms, diagnosis, treatment and the prognosis.

Secondly, characterize form of cancer such as ovarian cancer, the evidence that can support this reason; ovarian cancer is a disease which cancerous cells are found in the ovaries, the cancer genome atlas project after analysis of messenger RNA, micro RNA and DNA sequences, they have characterized an ovarian cancer by a mutation in most tumors, and the project also identified a periodic somatic mutations in