Medscape: The Cause Of MS Disease

Multiple sclerosis, also known as MS, is one of humankind’s most mysterious diseases. No one knows the exact cause and there is no exact treatment. Still multiple sclerosis has the ability to affect nearly 3 million people worldwide and at least 500,000 people in the United States (Boroch). This disease tends to be more common in individuals of northern European descent and women are more than twice as likely to develop multiple sclerosis as men. Of those 3 million people, most of them are between the ages of 20 and 50 years old (Dangond). Even though multiple sclerosis is a mystery disease, scientists are working to determine the exact cause and treatment.

MS is characterized by the destruction of myelin, inflammation in the CNS and the formation of lesions in the CNS.

MS is usually occurs at age of 15 to 55 with the average onset at about 30 years of age. Women are twice more likely than men to develop this debilitating autoimmune disease (Love, 2006). Due to the heterogeneity of the disease, where it can affects many sites of the CNS such as the brain cortex, brainstem, spinal cord as well as the optic nerve, thus the clinical symptoms of MS are widely ranged.

Multiple Sclerosis (MS) is a chronic inflammatory disease of the central nervous system. MS affects approximately 3.0 million people globally, with about 300,000 cases in the United States. Twice as many women as men have MS. The average ages for onset of MS is 20-40 years. In MS, cells in the immune system attack and destroy myelin, the fatty tissue surrounding nerve cells (http://www.phylomed.com/MS.html). Scar tissue replaces the myelin, interfering with the transmission of nerve signals and leading to numbness, fatigue, spasticity, loss of muscle control, and various other debilitating symptoms. There are four broad theories

MS(Multiple Sclerosis) is a disease which gradually hardens all tissues and also causes scars. These scars form when the persons immune system's cells go into the central nervous system and cause inflammation to the brain, spinal cord and optic nerves. MS is also a non contagious and unpredictable disease. MS is also the most common chronic disease (when it comes to the CNS (Central Nervous System)) with young Australians. Throughout all the states of Australia, Victoria is the State with the most people that have the condition.

The causes for multiple sclerosis is unknown. It is an auto immune disease, which the immune system of the body attacks its own tissues. Multiple sclerosis is caused by damage of the myelin sheath. When the nerve covering is damaged, the nerve signals stops or slows down. The inflammation is caused by a nerve damage. This occurs in any region of the brain, optic nerve, and spinal cord. Women are more affected than men. Commonly diagnosed between ages 20 and 40, but it can be seen at any age.

Multiple Sclerosis, commonly known as MS is an autoimmune disease of the central nervous system. Scientists have been studying MS since the 19th century. In MS, the body’s immune system produces cells and antibodies that attack myelin in your brain which is essential for the nerves in your brain and spinal cord to conduct electricity to perform its function. The attack on myelin results in vison loss, paralysis, numbness, muscle weakness, difficulty walking, stiffness, spasms, and bladder and bowel problems. MS has varying degrees of severity and affects people between the ages of 20-50, mostly women. Although there are treatments, there is no cause and cure yet.

Multiple sclerosis is an unpredictable, crippling neurological disease of the central nervous system, which affects the flow of information within the brain, and between the brain and body. The name is this disease refers to multiple areas of scarring throughout the brain and spinal cord. This scarring is a result of what happens when the body attacks itself. A substance called Myelin surrounds the nerves to help protect them (Healthline.com, 2015). Multiple Sclerosis is thought to occur in a genetically susceptible individual (although there is no evidence to show that the disease is directly inherited) influenced one or more environmental factors. MS is thought to be an autoimmune disease, however others disagree as the target of the immune

MS is an autoimmune disease, meaning the immune system attacks the bodys own myelin sheath protection. The damaged myelin and axon fibers is caused by overactivated T cells.

If you know anyone with Multiple Sclerosis or MS, you would know how terrible the disease is. Multiple Sclerosis is an inflammatory disease in which your immune system attacks the nerve cell covers in the brain and spine are damaged. The nerves in the body eventually deteriorate and it is fatal. According to the National Multiple Sclerosis Society, the cause of Multiple sclerosis is still unknown. There is not a cure at the moment for Multiple Sclerosis, but there are treatments that can speed recovery when attacked by the disease (Mayo Clinic). Scientists are under the impressions that there are a few factors that may come into play. They say that when they discover the exact cause of Multiple Sclerosis it will be easier to find a way to treat the disease or maybe even stop it from happening at all. (National Multiple Sclerosis Society)

Scientists are investigating many factors, including geographic, demographic changes (age, gender and ethnicity), infections, and more, to try to understand the reason of this evidence. This was discovered for example that people born in geographic areas designated as high risk of developing multiple sclerosis, but then have moved in a geographic area with a lower risk before the age of 15 years, they have acquired risk related to the new area. This suggests that exposure to environmental factors before puberty, predispose a person to develop multiple sclerosis later.

Etiology is the cause or set of causes of a disease or condition. The cause of MS is unknown but it is likely that multiple factors are a cause for it. The first cause is immunologic. Multiple Sclerosis is considered an immune-mediated disease meaning the immune system malfunctions and attacks the central nervous system. Researchers know that the myelin sheath is directly affected, but they do not know what triggers the immune system to attack the myelin. The second possible cause is genetic, several genes play a role in MS. The chance of developing MS is slightly higher if a close relative, such as a parent or a sibling has the disease. According to the Multiple Sclerosis Foundation if one parent has MS, the risk of their children getting it is estimated to be between two and five percent. Many scientist believe that people with MS are born with a genetic susceptibility to react to certain environmental agents. A third possible cause is environmental. Some scientists believe vitamin D may play a role. Studies show that there has been an increase of MS cases in countries that are located further from the equator; people who

Multiple Sclerosis has the structures and functions and malfunctions that affect the body system. MS is two out of three times more common in women than men. MS is a disease that affects the nervous system. The scientists are researching for a cure but don’t have one yet. MS can cause a lot of pain, numbness, and weakness that occurs on one side of the body, or leg and trunk. Researchers believe that MS affects more than 2.3 million people worldwide.

The cause of Multiple Sclerosis is still unknown. A combination of factors may play a role in causing this disease such as the immune system, environment, infectious diseases and genetics (Stachowiak, 2014). MS is an “abnormal immune-mediated response that attacks the myelin coating around nerve fibers in the central nervous system, as well as the nerve fibers themselves” (National Multiple Sclerosis Society, 2014). Scientists are further investigating the immune-mediated process. Environmental factors, such as vitamin D, play a role in MS. For instance, MS occurs more frequently in those who live further away from the equator. “Infectious diseases, such as viruses, are recognized as causes of demyelination and inflammation, a

The first case of multiple sclerosis (MS) was found in 1849. This disease is not contagious, but epidemiologists have identified some factor such as gender, generics, age, geography and ethnic background that may help determine what cause this disease. MS affects more than 2.3 million people worldwide of those women are more likely than men and people who lives in the north. The average age for women are between 20 to 60 years old. It is important to know that the multiple sclerosis does not have cure and is a chronic