Melanin

Many people think that is it possible to achieve a “healthy tan,” but this thought has been proven wrong. Overexpose to UV-A and UV-B rays from the sun lead to premature aging of the skin, as well as the possible formation of skin cancer, know as melanoma. An appearance of a tan is actually a stage of burning and damage to the skin. Although a tan may be desirable to many, the fact remains that more people need to be educated on the dangers of the sun’s harmful rays, and the possible health complications of overexposure.

Chimpanzees have what is called melanin, which is a dark brown pigment that protects them from UV radiation. Melanin is a natural sunscreen, which filters out UV radiation. It is been proven that people with high concentration of melanin in their skin heading to come from tropical areas and it has protected them from skin cancer. After all of this research, Jablonski and Chaplin then ask, “what role melanin might play in human evolution?” (170).

It develops in the melanocytes, which are cells that produce melanin that gives the skin its pigment or color and protects tissues from ultra violet radiation. Dark skinned people have more melanin than light skinned people do. For this reason, Melanomia is more frequent in light skinned people. (“Detailed description “, 2000, P.2

5. In the film, Dr. Jablonski explains that melanin, located in the top layer of human skin, absorbs UV radiation, protecting cells from the damaging effects of UV. Genetics determines the type of melanin (i.e., brown/black eumelanin or red/brown pheomelanin) and the amount of melanin present in an individual’s cells. Based on this information, write a hypothesis for where in the world you would expect to find human populations with

Melanocytes are pigment-producing cells commonly found in your lower part of your outer layer of skin, which is known as the epidermis. The natural color of your skin is produced by melanin. When skin is being exposed to

Melanoma is caused by over exposure to UV which can sometimes cause sunburn, it can be especially critical to those whom are inclined to the disease itself. The tumours derive in the pigment-producing melanocytes which are inside the basal layer of the

Although there are several types of skin cancer, the most aggressive form is melanoma. This cancer of the skin involves mass replication of the pigment producing melanocyte cells, which are located in the epidermis, below the basal layer. There are several factors involved with the onset of melanoma including, exposure to ultraviolet rays, genetic predisposition, numerous nevi (moles), immunosuppression, and environmental exposure to carcinogens.

Vitiligo is an auto-immune disease where melanocytes, the cells that make pigment in the skin, are destroyed (Vora, Patel, Chaudhary, Mehta & Pilani, 2014). It is characterized clinically by totally white patches of skin, also known as lesions, appearing primarily on visible areas of the body, including face and hands (Osman, Elkordufani & Abdullah, 2009). In very rare cases vitiligo is accompanied by itching or other somatic symptoms but gradual discoloration is generally its only physical symptom (Schmid-Ott et al., 2007). The patches develop unpredictably and while there is a genetic component to vitiligo, race and age do not affect the incidence of the disease (Gupta, Sreenivas, Mehta, Khaitan & Ramam,

Melanocytes, embryologically derived from the neural crest, are distributed in the epidermis and thus are found throughout the skin. They produce a brown pigment known as melanin and are responsible for racial variation in skin color and also the color of moles. Malignant degeneration of

Scientists do not fully understand Vitiligo yet; they are still trying to find out why it occurs. Evidence points towards the conclusion that it is an autoimmune disorder, in which the body’s immune system mistakenly targets the melanocytes in your body. The changes in the skin can vary from patient to patient, being that

A major function of melanin is to act as a defensive barrier of the skin against radiation damage. Ultraviolet light between the wavelengths 280-320nm (UV-B) causes sunburn and damages the skin on nonpigmented peoples. Exposure to this degree of light causes their skin to become dry, leathery, and wrinkled in appearance similar to that associated with aging. This can be seen in Whites living in Australia and South Africa, where ultraviolet light intensity is high because of the relative latitude or closeness to the equator.

Although very informative, I nearly lost interest in the subject as it was a bit dry, however, with the incorporation of pictures, I was able to grasp the science of how this structure functions and the significance of melanin, “the most important substance imparting color to skin” (9). Melanin is formed in cells called melanocytes, located between the dermis and epidermis; these cells produce different amounts of melanin and this is the main reason why people have different skin colors (11,14). The author breaks down the scientific terms in a clear and coherent

Around the world, cutaneous melanoma is predominently a disorder of people with sensible skin and sensible hair, who brown ineffectually; in every way that really matters all the known threat segments are joined with sun presentation and skin helplessness to sun and there is small expounding on the event of melanoma in dull cleaned populations. Melanoma overall happens more routinely

Vitiligo is a multifactorial polygenic disorder with a complex pathogenesis. It is related to both genetic and non genetic factors. Although several theories have been proposed about the pathogenesis of vitiligo, the precise cause remains unknown. Generally agreed upon principles are an absence of functional melanocytes in vitiligo skin and a loss of histochemically recognized melanocytes, owing to their

Vitiligo is an acquired depigmentation disorder of skin and hair. It is a cosmetically disfiguring disease caused due to melanocytes destruction [Moretti et al., 2002], however, the pathogenesis of such disease is still conflicting.