Melanoma Research Paper

Many people think that is it possible to achieve a “healthy tan,” but this thought has been proven wrong. Overexpose to UV-A and UV-B rays from the sun lead to premature aging of the skin, as well as the possible formation of skin cancer, know as melanoma. An appearance of a tan is actually a stage of burning and damage to the skin. Although a tan may be desirable to many, the fact remains that more people need to be educated on the dangers of the sun’s harmful rays, and the possible health complications of overexposure.

Any type of change size, color, or shape of a mole is an important warning sign. For weeks or months, watch the changes that occur. The ABCDE rule is a helpful rule to estimate skin changes. A is asymmetry. If one half of a mole does not match the other have there is no symmetry. B is border irregularity. Jagged, uneven, or blurred edges of a mole should catch your attention. C is color. Changes in the mole color, particularly from the edge of the mole to the middle. D is for the diameter. If the mole is larger than 6mm the mole should be of concern. E is evolution. Changes in the surface size and shape, as well as itching or tenderness should be observed. Often time’s melanoma is developed in unmarked skin, but can also develop in existing moles or birthmarks (“Melanoma and Skin Cancer Symptoms”). Skin examinations should be an often routine provided by a doctor. Any notice of suspicious signs, see a health care provider as quick as possible. Examinations by a dermatologist are a potential way to see if you have developed skin cancer. If during the examination skin cancer is suspected a biopsy will probably be the next process (Knight).

Melanoma is caused by over exposure to UV which can sometimes cause sunburn, it can be especially critical to those whom are inclined to the disease itself. The tumours derive in the pigment-producing melanocytes which are inside the basal layer of the

Although there are several types of skin cancer, the most aggressive form is melanoma. This cancer of the skin involves mass replication of the pigment producing melanocyte cells, which are located in the epidermis, below the basal layer. There are several factors involved with the onset of melanoma including, exposure to ultraviolet rays, genetic predisposition, numerous nevi (moles), immunosuppression, and environmental exposure to carcinogens.

As many as ninety percent of melanomas are estimated to be caused ultra violet (UV) exposure. This includes UV exposure from artificial sources, such as tanning beds. “Strong evidence now links tanning beds to melanoma, a deadly form of skin cancer that afflicts nearly 69,000 Americans a year.”—USA Today. The more one tans and the younger one is your risk for melanoma increases. However, melanoma is increasing faster in women 15-29 years old, than in men the same age. Furthermore, 10,000 people die from melanoma. This is mainly caused because of tanning beds. As a matter of fact, a person dies every fifty minutes from melanoma, the second most common cancer. Tanning beds triple the risk of one getting melanoma. In fact, every time one goes and tans, the risk gets higher and higher. Following this further, more people get melanoma because of tanning beds than developing lung cancer because of

Have you ever felt the “false sense of security that [you] may not feel under direct sunlight” from a tanning bed (Jeffrey)? Your body relaxes, you feel serene, and you get a golden glow. Some teens strive for this feeling...and the tan. Tanning is the skin's response to injury, according to Arielle Kauvar, M. D. The exposure of UV rays over time can cause skin cancer. Skin cancer is the growth of abnormal growth of skin cells that forms in the tissue of the skin (Skin Cancer). Melanoma, the most dangerous type of skin cancer, can come from UV rays. From 1998- 2008, the number of cases of Melanoma has increased by about

In fact, “People who have ever used a tanning bed have a sixty-seven percent increased risk of developing squamous cell carcinoma and a twenty-nine percent increased risk of developing basal cell carcinoma. People who first use a tanning bed before age thirty-five increase their risk of melanoma by seventy-five percent” (Silecchia). In the past, melanoma mostly affected people in their fifties or older, but today, dermatologists see patients in their twenties and even late teens with this type of cancer. Experts believe this is caused by an increase in radiation from the use of tanning beds. A sunburn or intense sun exposure may also increase a person's chances of developing this deadly cancer. Being in the sun is inevitable, but people can still protect their skin from many forms of skin cancer by doing the simplest things such as applying sunscreen.

Melanoma is the most dangerous type of skin cancer. It develops when unrepaired DNA damage to your skin cells trigger genetic defects that lead you skin cells to multiply at a fast pace and form tumors. Melanoma can often resemble moles and some can come from previous moles. These melanoma moles can range in color from pink, red, brown, purple, white, blue and skin-colored, but more mostly seen as black or brown. It’s said that consumers who use indoor ultraviolent tanning devices are seven-four percent more likely to develop melanoma compared to someone who has never used a tanning bed before. Melanoma is usually caused from intense and over exposure to UV radiation. It has be estimated to kill around 10,000 individuals in the U.S. each year. The lifetime risk of melanoma is 1.5 times higher in males than in females. Melanoma is curable, if it is recognized early and

Melanoma is a dangerous invasive cancer which starts in melanin producing cells (melanocytes) usually located at the bottom of the skins epidermal layer. Although certain individuals have a genetic propensity for melanoma, it is usually triggered by excessive UV exposure from sunlight or tanning beds (Mayo Clinic, 2016a). At early stages it is relatively easy to treat, however, recurrences are common. At later stages melanoma treatments are less effective since it tends to metastasize and spread easily through the lymphatic system (Mayo Clinic, 2016a).. The root cause of malignant melanoma is due to mutations in the p53 gene protein which invariably leads to further mutations.

Indoor tanning exposes users to two types of UV rays, UVA and UVB. UVA rays are suspected to be linked to the development of melanoma and other skin cancers. Worldwide, there are more skin cancer cases due to indoor tanning than there are lung cancer cases due to smoking. Tanning causes damage to the DNA in our skin cells, which leads to abnormal growth that could be benign or malignant. Tanning also weakens our immune system which compromises our body's capability of fighting against malignancies and cancer cells. There are two types of skin cancer that can be caused by tanning- basal cell and squamous cell carcinomas. These types are treatable with early detection. Development of melanoma can be fatal."In the US alone, 419,254 cases of skin cancer can be attributed to indoor tanning. Out of this number, 6,199 are melanoma cases" (Skin Cancer Foundation). It has been found that younger tanners are at higher risk of developing skin cancers from tanning, but with the high levels of UV exposure, any tanner should take

It is usually caused by intense exposure from ultraviolet radiation such as sun or tanning beds. Melanoma is when damaged DNA from this high exposure triggers mutations in the body that leads to the intense multiplication of cancerous cells. Melanoma cancer can look almost like a mole and can range from skin colored to black or brown in color. If caught and treated early it is curable, however if not caught early it can spread into the body and cause other cancerous cells or death. There are four types of melanoma skin cancers: superficial spreading melanoma, lentigo maligna, acral lentiginous melanoma and nodular melanoma. Superficial spreading melanoma is the most common and is usually seen in young people, but in all ages as well. It is known for growing along the epidermis for a long period of time before penetrating into the skin. This can also be found almost anywhere on the body but usually for men on their upper bodies and for females on their legs but also upper bodies. Lentigo maligna is known for its appearance for can look similar to a tan or dark discoloration. It is usually found in the elderly population and is the most common in areas of Hawaii. It is found on the upper body, arms, facial area and ears. Acral lentiginous melanoma is known for its appearance under the nails, palms of the hands or feet as a dark discoloration. It is mostly common in Asian and African-American cultures and can

The article “Melanoma: Causes, Symptoms, and Treatments” written by Markus MacGill and reviewed by Dr. Helen Webberley is exactly what it states, an article on the integumentary disease melanoma. This article tells everything about melanoma, stating that it is a very deadly type of skin cancer. It is fortunate that it is the least common, however it is still responsible for the majority of skin cancer related deaths each year. Melanoma comes from pigment-producing cells that have mutated into a cancerous cell. They spread quickly, almost too quickly to catch. Skin cancer is first noticed by the look of the skin, then can be confirmed or denied with testing. Melanoma may not produce symptoms. Staying out of the sun for extended amounts of time is best when avoiding skin problems, especially skin cancer. Melanoma is seen mostly in people over the age of forty, and favors women. It can develop anywhere on the skin but does favor the trunk of men and the legs of women. Melanoma will form changes in existing moles on the skin. People should be checking for noticeable differences in skin constantly, especially those who have a known risk. Some early indicators of melanoma could be pale skin, light eyes, numerous moles, multiple freckles, sun exposure, light hair, age, and a few more. Sadly, most these are unavoidable.

Melanoma is cancer that begins in the melanocytes. Other names for this cancer include malignant melanoma and cutaneous melanoma. Most melanoma cells still make melanin, so melanoma tumors are usually brown or black. But some melanomas do not make melanin and can appear pink, tan, or even white. This type of cancer can develop anywhere on the skin, but they are more likely to start on the chest/back in men and on the legs in women. The first sign is the appearance of a flat or slightly raised discolored patch that has irregular borders and is somewhat asymmetrical in form. The color varies, and you may see areas of tan, brown, black, red, blue or white.

It arises from the melanocytes. Melanomas often resemble moles and it is very important to know the difference between the two. Melanomas are usually black or brown but can also be skin-colored. They form a large flat spreading lesion with a rough border. On the contrary, a mole usually has an organized color and even contour, and no longer than the end of a pencil eraser (6mm). The greatest risk factor is those who are genetically predisposed to the disease. It occurs more in men, redheads, and severe UV exposure experiencing severe sunburn as in childhood. An oncogene called BRAF is responsible for ⅔ of cases of melanoma in men although it does not appear to trigger melanoma in woman although it has been connected to some breast cancer and ovarian cancer in women. The BRAF mutation is commonly found in moles. To recognize melanoma The American Cancer Society created an “ABCD rule”: A for asymmetry-irregular shape; B for border irregularity-not smooth but wavy, wrinkled, scalloped or rough. C for Color- black, brown, skin colored-tan, and even sometimes red or blue; and D for diameter greater than 6mm. The survival rate of metastatic melanoma is slim with the average patient living only 6 months after diagnosis and only around 5-14% surviving after 5 years (Saladin,

C. Melanoma Skin Cancer is the most dangerous form of skin cancer, it kills one person per hour, these cancerous growths are most often caused by ultraviolet radiation from sunshine or tanning beds. These tumors originate in the pigment-producing melanocytes in the basal layer of the epidermis. Melanoma is caused mainly by intense, occasional UV exposure (frequently leading to sunburn), especially in those who are genetically predisposed to the disease. Often the first sign of melanoma is a change in the size, shape, color or feel of a mole.