Meningiomas Research Paper

Once a person has been diagnosed with brain cancer, treatment should begin immediately. Treatment for brain tumors involves any combination of surgery, radiation, and chemotherapy. Some tumors require several different surgical procedures; some can be treated with radiation alone. Surgery is the best process to remove a brain tumor. Surgery attempts to remove most, if not all of the tumor. Once most of the tumor is removed, the rest of the tumor can be removed through a process called radiotherapy.

There are over 12,000 cases diagnosed each year.Once an MRI is taken and the mass is seen, this can only be diagnosed definitively once surgery has taken place and they have taken a sample and put it under a microscope to determine grade. The single hardest part to remove while in surgery is known as the feelers, they are thin like tentacles that grow out from the tumor and imbed themselves into the surrounding brain tissue. It is mostly defined in the brain area and rarely goes anywhere else in the body. the highest grade is four how they make that determination is taking the sample, while looking under a microscope to see how it

Glioblastoma is the most common and aggressive form of malignant brain cancer in adults. On average, 8 of every 100,000 people in the U.S. are diagnosed with glioblastoma every year – representing approximately 2% of all cancers diagnosed [1]. Glioblastoma tumors form when astrocytes, star-shaped cells which support and protect the brain, re-enter the cell cycle and start to rapidly divide. Because the brain is supported by a large network of blood vessels, tumors grow quickly and are difficult to remove surgically. Present treatments for glioblastoma are limited to surgery, radiation therapy, and chemotherapy; however, despite these interventions tumors are likely to regrow. Consequently, typical survival time following glioblastoma diagnosis is less than 2 years.

The American cancer society estimated that 18,500 people would be diagnosed with brain tumor and those 12,760 men and women would die of brain cancer in 2005.The National Cancer Institute (NCI) estimated that 22,070 new cases of brain and other central nervous system (CNS) cancers would be diagnosed in the United States in 2009. The American Brain Tumor Association (ABTA) clarifies this statistic further by estimating that 62,930 new cases of primary brain tumors would be diagnosed in 2010. By the year 2030, there will be 26 million new cases, and the death toll will reach to around 1.7 million people. According to World Health Organization (WHO), there are more than 120 types of brain tumors.

ncidentaloma is a tumor that does not show any symptoms until it is discovered by some types of examinations that were not previously planed. Adrenal cortex, a part of the adrenal gland, is where most of the adrenal tumors develop. Adrenal cortex tumors can have either benign or cancerous properties.

This year it is estimated that roughly 24,000 adults in the United States alone will be diagnosed with primary cancerous tumors of the brain or spinal cord (Brain Tumor: Statistics) . Brain related cancers are the 2nd leading cause of death for men up to age 39 and women up to age 20 (Brain Tumor Primer) . There are two types of tumors, benign and malignant. Each tumor has a different possible treatment method. Malignant tumors may require surgery, chemotherapy and radiation therapy, while benign tumors may only require surgery. There are also various clinical trials for malignant tumors, one of which involves combining the chemotherapy medication temozolomide with radiation therapy to treat the tumor, or at the very least slow the growth

“Patients can face modifications in their quality of life due to frequent headaches, nausea, seizures, neurological or cognitive deficits, and insomnia. Furthermore the treatment itself is often toxic and can result in considerable morbidity” (Gazzotti, Mariana, 2011). “Until recently, assessment of treatment response in brain tumor patients has been associated almost exclusively with radiological imaging response (characterized by tumor reduction in tumor dimensions), progression with symptoms and overall survival” (Gazzotti, Mariana, 2011). “In addition, quality of life may also reflect cognitive dysfunctional and functional limitations associated with the disease or as a treatment complication in these patients” (Gazzotti, Mariana, 2011). People suffering from brain cancer already go through an immense number of complications dealing with their disease alone, and the surgeon should really focus on the impact of treatment on the patient’s quality of life. Some common risks of Brain surgery are: bleeding of the brain, blood clots, brain swelling, coma, impaired speech, vision, coordination, or balance, and many more risks are

The diseases associated with FUBP1 include oligodendrogliomas, astrocytomas, and oligoastrocytomas. Oligodendrogliomas are primary glial brain tumors and can be either low-grade (grade II) or high-grade (grade III). [2] Since oligodendrogliomas have a slow growth rate, they are often present for years before they are diagnosed. Nevertheless, the most common symptoms include: seizures, headaches, and personality changes. Altogether, the symptoms vary by location and size of the tumor. About 66 to 78 % of people with grade II oligodendroglioma survive for about 5 years after diagnoses, while 30 to 38 % of people with grade III will survive for about 5 years after they are diagnosed. [3] Astrocytoma is another type of brain cancer that stats in the cerebrum, which is the largest part of the brain, but can also appear in the cerebellum, which is the back of the brain. It is more common in men than in women. Like oligodendrogliomas, the most common symptoms of astrocytomas include: headaches, seizure, changes in behavior and memory loss. [4] Prognosis of astrocytomas depends on the type of astrocytoma. Altogether, a low-grade astrocytoma (LGA) has an 83 % 10-year overall survival, while the overall survival rate of a high-grade astrocytoma (HGA) range between 15-20%. In both oligodendrogliomas and astrocytomas, the FUBP1 locus is mutated which leads to the inactivation of

On April 14, 2012, my husband was diagnosed with a Glioma Brain Tumor. Even three and a half years after his diagnosis, I still don’t really know much about Gliomas, so I have decided to research this topic.

Menkes Disease is a mutation on the ATP7A gene; the mutation creates an X-linked recessive trait that affects multiple systems in the body. As expected of an X-linked recessive trait a majority of the patients affected by this disease are males. The phenotypes for this disease are sparse and kinky hair that is gray in color. This due to the diseases impairment of the metabolism of copper in the body. The prognosis for this disease is usually death before three years of life, however, early copper–histidine treatment can cure some neurological symptoms that are associated with the disease.

My options were straightforward: undergo surgery to remove the tumor, or simply do nothing and wait for medicine to work its magic. Option one was hands down a “no way, José” in my perspective. It was risky and I would need a long recovery period. I did not want anything to interfere with my education. On the other hand, I was haunted by the prospect of keeping this tumor in my brain. A series of wild thoughts went on in my mind--What if the doctors gave

The overall prognosis of this tumor is not optimistic with mean survival sitting between 6 and 11 months [52]. This diagnosis is most often associated with infants and young children. Given the significant neurologic complications of radiation to the developing brain, physicians are often hesitant to radiate. Furthermore, the efficacy of chemotherapy has been historically difficult to quantify given a wide variety of regimens used with few patients enrolled in each study [53].

Medulloblastoma, also called cerebellar primitive neuroectodermal tumor (PNET), is a fast growing embryonal tumors[A] located in the cerebellum caused by a glial cell (1)(4). The seven types of medulloblastoma are, classic,desmoplastic, nodular,, large-cell,(anaplastic), neuroblastic, glial differentiation, medullomyoblastoma, and melanotic. According to American Brain Tumor Association, medulloblastoma is relatively rare, and only accounts for two percent of all primary brain tumors(1).However, medulloblastoma is common in children making up to twenty percent of childhood brain tumors(2), while it is less common in adults(1). It is also more common in men than in women(3). (Thesis)

Common malignant brain cancers increase significantly according to statistical data collected by the National Cancer Institute. In 1984, the annual incidence rates of primary brain tumor and primary brain lymphoma also increased notably, the rate of lymphoma almost tripling,

Great discussion here. As Greg correctly pointed out, there is no right or wrong answer. But I have to say that I would be more tempted to read an article that leads with an impacting story or information, such as that healthy teenagers can succumb to meningococcal meningitis in a matter of days, or that meningitis is a potentially deadly disease that affects x number of people each year, than an article that leads with information about what a company has been doing to raise awareness about the disease. I believe that the risk that the disease imposes would resonate more with readers, especially mothers, leading them to want to learn more what to do to prevent it.