Meta Analytic Connectivity Of Bilateral Thalamus

2069 Words Sep 18th, 2014 9 Pages

Meta-analytic Connectivity of Bilateral Thalamus

The aim of our study was to compare and characterize the coactivations of LT and RT. By performing a conjunction analysis LT∩RT we found that each of our ROIs shared coactivations with cerebellar-thalamic-cortical circuit. Within the cortex, convergence of LT and RT MACAMs occurred in right superior temporal, right and left precentral, bilateral parietal and left supplementary motor area, which is involved in cognitive aspects of performance (Kim et al., 1994; Mushiake and strick, 1995; Gao et al., 1996; for review, see Middleton and Strick, 1997) such as working memory, planning, and rule-based learning (Middleton and Strick, 2001). Importantly, LT and RT individually showed specific and distinct connectivity patterns. While precentral gyrus connectivity is common to both LT and RT MACMs, it was more strongly connected with LT. LT seed also demonstrated significantly greater coactivation with bilateral putamen, left inferior and supplementary parietal and left postcentral. The coactivation of the ventral lateral nucleus (VL) of the LT composed of a network of specific cerebellum-subcortical-parietal-frontal structures which is involved in the mental grammar, which subserves the rule-governed combination of lexical items into higher order representations, underlies procedural memory, which supports the learning and execution of motor and cognitive skills, especially those involving sequences (Ullman, 2004).…
Open Document