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Methotrexate Essay

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as “Predictors of Success of Methotrexate Treatment in Women with Tubal Ectopic Pregnancies.”7 The objective of this study is determining the institutional success rate with single-dose intramuscular methotrexate therapy for the treatment of ectopic pregnancy and to identify predictors of treatment outcome. This research was a retrospective study which reviewed consecutive patients who were treated with methotrexate from 2000 to 2002. Their treatment success was defined as complete resolution of ectopic pregnancy without the need for surgical intervention. The result of the study was success rate of 85% (69/81 patients). Women in which their treatment was successful their pretreatment serum beta-human chorionic gonadotropin (HCG) level was lower compared to those were treatment was not successful (793 vs 3804 mIU/mL, P 2000mIU/mL), history of…show more content…
The leaflet contains a methotrexate contraindication list where
Methotrexate cannot be used in ectopic pregnancy such as : in ruptured ectopic pregnancy, hormones (HCG and others ) are above the optimal limit for using methotrexate, larger ectopic sac, liver and kidney dysfunction and abnormal CBC. The leaflet mentions the advantages of using methotrexate in ectopic pregnancy like: It has a worthy rate of success in treating small ectopic pregnancies, Avoids surgery & the associated risks of having a general anesthetic. It offers the best chance of maintaining fertility after treatment without the need for hospital visits10.

In summary, Methotrexate is a successful significant management option for ectopic pregnancy in many cases supported by multiple RCTs by stopping the cells of the pregnancy to be proliferated ) leading to the pregnancy being absorbed). This makes it an effective medicine that should be considered in treating stable patients with ectopic
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