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Molecular Basis Of Biology And Biotechnology

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MOLECULAR BASIS OF HEPATOPROTECTIVE AND ANTIOXIDANT ACTIVITIES OF SELECTED MEDICINAL PLANTS FOLLOWING CCL4-INDUCED HEPATOCELLULAR DAMAGE IN MICE

ELIAKIM MBAKA (MSc.)
I84/29467/2014
DEPARTMENT OF BIOCHEMISTRY AND BIOTECHNOLOGY

A proposal submitted in partial fulfillment of the requirement for the award of the degree of Doctor of Philosophy (Medical Biotechnology) in the School of Pure And Applied Sciences of Kenyatta University

May 2015
Declaration
This research proposal is my original work and has not been presented for a degree in any other university
Name: Eliakim Mbaka Signature………………….. Date………………. I84/29467/2014

SUPERVISORS:
This proposal has been submitted for review with our approval as supervisors
Dr. Mathew Piero Ngugi
Department of Biochemistry and Biotechnology,
Kenyatta University
Signature………………………………… Date …………………………………..

Dr. David N Mburu
Department of Biochemistry and Biotechnology,
Kenyatta University
Signature………………………………… Date …………………………………..

Dr. Richard Oduor
Department of Biochemistry and Biotechnology,
Kenyatta University
Signature………………………………… Date ………………………………….. Contents
Declaration ii
LIST OF ABBREVIATION AND ACRONYMS v
ABSTRACT vi
CHAPTER ONE: INTRODUCTION 1
1.1 Background of information 1
1.2 Problem statement 4
1.3 Justification 5
1.4 Hypothesis 6
1.5 Objectives 6
1.6 Significance 7
CHAPTER TWO: REVIEW OF LITERATURE 8
2.1 Overview of liver functions 8
2.2 Hepatotoxicity 8
2.3 Conventional and Traditional

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