MOLECULAR BASIS OF HEPATOPROTECTIVE AND ANTIOXIDANT ACTIVITIES OF SELECTED MEDICINAL PLANTS FOLLOWING CCL4-INDUCED HEPATOCELLULAR DAMAGE IN MICE
ELIAKIM MBAKA (MSc.)
I84/29467/2014
DEPARTMENT OF BIOCHEMISTRY AND BIOTECHNOLOGY
A proposal submitted in partial fulfillment of the requirement for the award of the degree of Doctor of Philosophy (Medical Biotechnology) in the School of Pure And Applied Sciences of Kenyatta University
May 2015
Declaration
This research proposal is my original work and has not been presented for a degree in any other university
Name: Eliakim Mbaka Signature………………….. Date………………. I84/29467/2014
SUPERVISORS:
This proposal has been submitted for review with our approval as supervisors
Dr. Mathew Piero Ngugi
Department of Biochemistry and Biotechnology,
Kenyatta University
Signature………………………………… Date …………………………………..
Dr. David N Mburu
Department of Biochemistry and Biotechnology,
Kenyatta University
Signature………………………………… Date …………………………………..
Dr. Richard Oduor
Department of Biochemistry and Biotechnology,
Kenyatta University
Signature………………………………… Date ………………………………….. Contents
Declaration ii
LIST OF ABBREVIATION AND ACRONYMS v
ABSTRACT vi
CHAPTER ONE: INTRODUCTION 1
1.1 Background of information 1
1.2 Problem statement 4
1.3 Justification 5
1.4 Hypothesis 6
1.5 Objectives 6
1.6 Significance 7
CHAPTER TWO: REVIEW OF LITERATURE 8
2.1 Overview of liver functions 8
2.2 Hepatotoxicity 8
2.3 Conventional and Traditional
Charles W. Upham, George Kittredge, Paul Boyer, Stephen Nissenbaum, Linnda Caporael, Carol Karlsen, Peter Charles Hoffer, and Emerson Baker are all experts in their selected fields. They
What field/program are you studying at Guilford Technical College and why did you choose it?
I, Andrew Khanano, of sound mind, declare that the work submitted is of my own work, and all resource and information used has been appropriately cited.
I would wish to acknowledge ……University, school of ……..and more particularly to the Department of ……….for offering me this unit, research proposal in compliance with the requirements for award of degree. I also want to thank my supervisor … for assisting me in developing this project proposal to the best of my standard.
the event that the purpose of your paper is to develop a new questinnaire, you may wish to
Balasubramanian, D., Bryce, C.F.A, Dharmalingam, K., Green, J. & Jayaraman, K. (Eds.) (2004). _Concepts in Biotechnology_ (2nd ed.). India: University Press
1. Due by Day 7. Outline of Final Paper. Review the Final Paper instructions in Week Five of the online course or in the “Components of Course Evaluation” section of this guide. Then, visit the Ashford Writing Center located under the Learning Resources tab on the left navigation toolbar in your online classroom. Review the “Sample: Outline.” Format your outline for the Final Paper according to the “Sample: Outline.” (NOTE: In the “Sample: Outline,” it states that the thesis statement is the last one to three sentences of the introduction. However, the thesis
Additionally, while I am still in the very early stages of constructing a proposal, I hope to pursue undergraduate research that investigates the
Scientists continue to find new ways to insert genes for specific traits into plant and animal DNA. A field of promise—and a subject of debate—genetic engineering is changing the food we eat and the world we live in.
This document is available in alternative formats upon request. Please contact the originating department or school of study.
Prize’s are put into place to award gifted beings; whose work has or will make a significant change in mankind. Most importantly, they are recognize by their genius and not judging their area of expertise. When the awarded person wins the prize, there is always a level expectation that is expected of them. In the history of science, there have been many achievements that have motivated by human to not only live to the fullest of their potential but to live as long and healthy life as they can. These victories in medicine have started the courage for all human being all over the world having the confidence to live their lives without a disease or bacteria infection that now days can be cured without any problem taking their life. Given Antony Van Leeuwenhoek along with his many contributions to science, there is no better nominee for an award that demonstrated the constitutional achievements in biotechnology. A tradesman and inventor in the biotechnology society he is undeniably deserving of The Carleton Prize of Biotechnology. Antony van Leeuwenhoek’s experimentation of lenses for microscopic research, and his inventions which increased magnification, research and development there would be many unanswered question in the medical world.
1Department of Veterinary Physiology and Biochemistry; Karnataka Veterinary, Animal & Fisheries Sciences University; Veterinary College, Vinobanagar, Shimoga- 577 204, India, 2Division of Biochemistry, 3 & 4Division of Veterinary Biotechnology, Indian Veterinary Research Institute, Izatnagar-243 122, Bareilly, Uttar Pradesh, India
[Note: This sample proposal is based on a composite of past proposals, simulated information and references, and material I’ve included for illustration purposes – it is based roughly on a fairly standard research proposal; I say roughly because there is no one set way of creating a quantitative research proposal. Much of its design is based on the nature of the research, your preferences, and your decisions regarding how to describe or portray what it is you plan to accomplish. The material in this document was adopted from a dissertation proposal created by Dr. Ralph Brockett. A biography
Sociogenomics is a relatively new research area that isn 't very well understood. Scholarly articles (e.g., Roberts & Jackson, 2008) describe it as a field that explores the following: the identification of genes that influence social behavior, the understanding of the influence of these genes on underlying neural and endocrine mechanisms, and understanding the effects of the environment, particularly the social environment, on gene action.
The chapter three of the book provides measures which the research candidate should maintain when presenting his/her proposal to the research supervisor. The authors mentioned the major features which should never be avoided which they listed and explained as follows;