Most Common Auto Immune Disease

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Rheumatoid arthritis (RA) is a systematic inflammatory disease characterized by synovitis (constant inflammation of the synovial membranes) and autoantibodies. The disease that affects 0.5-1.0% of all adults in industrialized countries, mostly women and elderly people (Scott et al, 2010). In the United States, more than 1.5 million people suffer from rheumatoid arthritis, making it one of the most common auto-immune disease (Carmona et al. 2010). According to the Arthritis Foundation, individuals who suffer from arthritis have to deal with joint pain, morning stiffness, fatigue, loss of appetite, depressive symptoms, and low-grade fever which can last a few days to weeks. Individuals with this disease tend to have a low-quality of life and difficulties with day-to-day activities. There are 5 types of RA progression measured by imaging radiography. Type 1 is identified as a rare type, with no radiographic progression, type 2 is a slow or moderate onset with increasing progression, type 3 is a moderate-to-fast onset with stable progression, type 4 is a fast onset with a decreased progression rate, and type 5 is a slow onset with acceleration in progression, then deceleration (Graudal et al, 2004). Having any of the five types of RA can cause disability as a result of joint damage, lowers quality of life, and can lead to other comorbidities such as cardiovascular disease, tuberculosis, malignancies, and mental health conditions such anxiety and depression (Scott et al,
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