Most Common Types Of Hemophilia

Symptoms of hemophilia that would require urgent action and would be considered emergencies could include some of the following: sudden pain, swelling, or warmth of the joints, extremely painful headache, vomiting, extreme fatigue, neck pain, and/or double vision. These symptoms would suggest that urgent action should be taken (Mayo Clinic, 2014).

Hemophilia is a rare disorder when blood doesn't clot normally because it is short on sufficient blood-clotting proteins. Deep bleeding inside the body is big concern especially in the knees, ankles and elbows. The internal bleeding caused from this can damage the organs and tissues of the body and may be life threating. When a person without Hemophilia is injured, a system of procedures happens to make the blood turn from liquid to solid to clot the wound and make the blood flow stop. Platelets, which are cells found in the blood, combine together to form a clot at the site of bleeding. The platelets hold an enzyme that causes fibrinogen to change to fibrin which is a solid substance that doesn’t liquefy. The fibrin goes to the area of injury

Hemophilia is a genetic disorder that slows the process of blood clotting. The majority of sufferers bleed extensively after injury or medical operation. In serious cases, there is spontaneous bleeding in the joints. “Milder forms of hemophilia do not necessarily involve spontaneous bleeding, and the condition may not become apparent until abnormal bleeding occurs following surgery or a serious injury.” (Genetics Home Reference) Males are more prone to Hemophilia. Two main types are Hemophilia A and Hemophilia B. Someone with Hemophilia A lacks clotting factor 8. Whilst people with Hemophilia B lack clotting factor 9. If one blood clotting factor is eliminated, the process of clotting falls apart. It can be compared with a chain reaction.

This kind of bleeding is very painful and may lead to joint deformity and arthritis. As the person with hemophilia experiences episodes, they are better to identify “a bleed” before there are any outward signs. For instance; As blood collects in the joint or muscle space, they may notice warmth, pain, and/or swelling to the area affected. For an infant or toddler the caretaker may notice some signs and symptoms suck as, swelling and warmth to an area of the body, blood in the urine or stool, unexplained irritability, or pain (“hemophilia”2002).

He cut his small toe when he was one year old. There was unusual bleeding. He was given a blood transfusion at a local hospital. He started bleeding frequently from different sites such as, his gums, nose and ears. At the age of four, he bled from his forehead and hip after a fall. He was tested at Christian Medical College Hospital, Vellore and he was diagnosed as having Type ‘A’ Hemophilia with severity at less than 1 %.

A. It 's important to know that hemophilia is not actually a disease or virus. https://my.clevelandclinic.org calls hemophilia "a rare hereditary (inherited) bleeding disorder in which blood cannot clot normally at the site of a wound or injury". This means that it is not contagious, rather it is passed down through genetics. When a hemophiliac gets injured,

Haemophilia is an inherited blood disorder in which the blood does not clot and the bleeding disorders are due to defects in the blood vessels, the coagulation mechanism, or the blood platelets. An individual who is suffering from the disorder may bleed spontaneously and doesn’t clot or may bleed for longer period as compared to normal, healthy person.

Hemophilia is an inherited genetic bleeding disorder that occurs due to deficiency of plasma coagulation factors causing lifelong recurrent bleeding episodes into joints, muscles, and closed spaces either spontaneously or following an injury.

Hemophilia is the name of a group of hereditary blood disorders that doesn’t allow the blood to clot normally (Frey 2009). More specifically hemophilia A, also known as factor VIII, is caused by a missing clotting protein coagulation factor VIII. It is often times referred to as the “Royal Disease” because of how it ran rampant through the royal families of England, Spain , Germany, and other European countries during the 19th and 20th century. Hemophilia A is inherited in X-linked recessive pattern. In males (who have only one X chromosome), one copy of the affected gene is enough to cause the condition. In females (who have two X chromosomes), a mutation on both of the genes would have to be present to cause the disorder. Because it is very unlikely that a female would have both altered copies on both of the genes females generally don’t get hemophilia. Since fathers can only pass on the Y chromosomes to their sons they can’t pass X-linked traits along (Hemophilia 2015). Hemophilia is linked to the mutation of the F8, on the X chromosome, as seen in Figure 1. Mutations in the F8 gene can cause faulty versions of the coagulation protein, therefore this protein cannot participate in the clotting process (Gersten 2014).

When an injury occurs in a patient with Hemophilia, blood pools to the injury site to clot the blood. If the patient has either deficiency factor IX or factor VIII, there is a possibility of activating the factor XI (Stachnik 218). With deficiency factor XI, there may be mild signs and symptoms. Hemophilia can also be caused by inheriting it from family members. Having a family history of Hemophilia can actually help determine if the baby, during pregnancy, has the disease (Mayo Clinic Staff 5). When a female who is a carrier for Hemophilia has symptoms of the disease, it is likely that she could pass her child the affected X chromosome with the gene mutation on the clotting factor (Hemophilia Facts 5). Most Hemophiliacs can tell if they have a family history; however, some families have no prior history. Families with no history would have to contain a carrier female but no affected males (2). In some cases, an affected father and a carrier mother can give the child a combination of chromosomes with a certain deficiency factor, which would result in an affected female child (Blachford 524). Hemophilia can also be caused by acquiring it.

Hemophilia A is a rare genetic disorder which results in blood not clotting normally because it lacks sufficient blood-clotting proteins also called clotting factors. People who have hemophilia A, tend to bleed for a longer time after getting injured because normally, the blood would begin to clot leaving the wound to heal. One of the main concerns for patients with hemophilia A, is the apprehension of internal bleeding. The most common areas to be found with internal bleeding are the knees, ankles, and elbows. Because these areas tend to be the first impact when we fall and get hurt, they would take most of the force leaving them with the majority of the internal bleeding. Internal bleeding is an issue because it can damage organs and tissue

Hemophilia is a disease in which blood clotting is severely reduced making any small injury a much bigger problem because it cannot clot by itself. The symptoms associated with this disease have to do with blood and how it clots or in this case does not. This disease is in effect whether the bleeding is internal or on the surface of the skin. Depending on the severity of the disease an affected person may bleed a little bit longer or much longer than someone who does not have hemophilia. This all depends on the amount of FVIII in the person's plasma.

Hemophilia : Normally the blood clots in a few seconds, but in Hemophilia which is a rare disorder the blood does not clot normally as it is deficient in blood clotting proteins also called the clotting factors.So in any case if you are suffering from Hemophilia then the blood will take a much longer time to clot than normal .Small injuries are not much of a worry but its of greater concern if there is any internal bleeding which may cause a severe damage to internal organs.

Listing from blood in the urine to nosebleeds and many others. More symptoms include deep bruises, blood in stool, excessive bleeding, pain in joints, and tight joints. Hemophilia is usually inherited which means that the parents pass the disease to their offspring. It is caused by a pairing up with a hemophilia gene if the mom has a normal clotting and the dad doesn’t he has the hemophilia gene. However if they have a child the child will not have hemophilia because the mom is dominant over the dad. It would be a genetic tendency because the mom and dad have genes that will join together and determine to see if their child will have

Symptoms of haemophilia in young children include, excessive gum bleeding while teething, excessive bleeding from cuts in the mouth and easy or unexplained bruising after falls. Usually children do not get spontaneous joint bleeding until after the age of two. As children get older the symptoms can extend to excessive bleeding when teeth are lost, blood in the urine, surface bruising and the previously mentioned spontaneous bleeding into joints and soft tissue. As children grow older they tend to find ways to keeps the symptoms from affecting their everyday life through experience (This does not mean that the haemophilia is any less severe). Treatments such as pain medications and factor replacement products can be used to lessen joint pain and to make the symptoms less severe, though there is no cure for haemophilia at this time. The severity of the disorder depends on the amount of the factor VIII protein is prevalent in the afflicted. The amount of factor VIII needed for a person to not have the disorder is 50% to 150%, the amount needed for a mild severity is 5%-40%, the amount needed for a moderate severity is 1% to 5% and the amount needed for a high severity is less than