Motivation and the Brain Paper

36). It has been established that addiction is related to several genes and that no one gene is considered a genetic marker for identifying those whom are at risk for developing alcoholism.

Relapses and drug taking are both heavily influenced by similar factors such as the drugs neurochemistry, the user’s history, environment, and dose of the pharmacokinetics. After a period of abstinence or non-use the drugs reinstating is more often an initiation of more than one factor, namely; re-exposure to drug, stress, cues in the environment, priming of the drug to user. In the user’s mind, neurochemical responses are commonly induced through these factors, in that they create a craving by mimicking the drug and this in turn prevents reinstatement and desire to use the drug (McGovern, Xie, Segal, Siembab, & Drake, 2006).

Addiction is thought of a biological nature that is past through genetics according to the biological theory as explained in P2. A contrasting theory of the biological theory would be the classical and operant conditioning theory, this was made by Pavlov. The basis of conditioning theories is that addiction is the end result of the reinforcement of drug use. The drug acts as a reinforcer and gains control over the user’s behavior. In contrast to the biological models of the exposure theories, these conditioning models suggest that anyone can show addictive behavior if they are given reinforcements, regardless of their genetics. The advantage of this

It is believed that certain individuals are predisposed or vulnerable to addiction based on biological, psychological and social influences. The euphoric high produced by many addictive substances is the result of overstimulation of the “pleasure center” of the brain. This is the same area that controls emotions, fear, self-control and overall feelings of wellness. The presence of these foreign chemicals creates a response that the brain will crave as soon as it fades. The brain’s chemistry works against its own health, as it rewires its decision making faculties around the primary goal of finding and taking more of the drug” (1). Many people mistakenly believe that psychological addiction is somehow less serious or real than physical addiction. The psychological aspects of addiction are much more challenging to repair and recover from than the physical addiction. Psychological addiction can last for years or even a lifetime.

To begin with, studies have found that inherited genes are responsible for a considerably large part of the probability that someone will become addicted to any kind of substance or behavior. Addiction is strongly influenced by genetic factors in the later stages of addiction, such as problem use and dependence of an addictive substance. Some genetic factors can make an individual more likely to become addicted to only one specific drug. On the other hand, some genes can make an individual more likely to become addicted in general. Some individuals might be genetically inclined to risk-taking behavior such as receiving large jolts of dopamine through what they consider to be the “excitement” of drug use. These individuals could be subject to keep returning to the illicit and harmful drugs that they find enjoyable despite what they know of the harmful effects. These genetic influences could make them more likely to become addicted to alcohol, cocaine, tobacco, gambling, or any number of substances or activities. Addiction has an inherited component and it

Genetic factors have been directly linked to the risk of an individual’s vulnerability to addiction (APA, 2008). In addition, other risk factors that play a

Wood, M.D, et. al (2007). Brief motivational intervention and alcohol expectancy challenge with heavy drinking in college students: A randomized factorial study. Addictive Behaviors, 32(11), 2509-2528. doi:10.1016/j.addbeh.2007.06.018

Genes and environment both prove to be important when determining who will be susceptible to becoming addicted to substances and who will not (Durand, Barlow, 2016, 388-389). Using drugs is based on environmental factors but becoming dependent on drugs will occur if a person is genetically vulnerable. There is no specific gene that can be held responsible for this phenomenon, but rather a group of genes that put one at risk for substance use disorder broadly. Susceptibility to addiction to one substance in particular does not occur. Psychological factors must also be considered when discussing what causes substance abuse disorder. Positive reinforcement (making one feel good) and negative reinforcement (making one feel less bad) are two primary reasons for continuing drug use.

Our genes are responsible for our hair color, health and behavioral characteristics. Passed on by our parents, these genes may also be responsible for addiction. Parents can pass on genetic traits that make their children predisposed to addiction.

The three stages of addiction are binge/intoxication defined by consumption and reward, withdraw/negative affect due to absence of the substance, and preoccupation/anticipation relating to the stage of seeking11. As such, the brain regions associated with each stage are the basal ganglia, extended amygdala, and prefrontal cortex correspondingly. The stages of addiction are cyclical, one leading to the next. The physical and psychological damage is magnified as the cycle is reinforced and strengthened with time

The purpose of this paper is to examine the article, “The Brain’s Rewarding System & Addiction” (2004) by Katharine P. Bailey, MSN. In this article, I did not find a general hypothesis. Studies in this article show that most drugs directly or indirectly cause selective elevation of dopamine levels in the nucleus accumbens (NA), the ventral tegmental area (VTA), and the limbic system, consequently called the reward center of the brain (Bailey, 2004). Behaviors that bring pleasure and are also crucial to existence (eating, drinking, and sex) also activate the same reward circuitry, however, activation of this circuitry by addictive drugs can be much

“Can Neuroscience Improve Addiction Treatment and Policies?” is a research that focus in the causes and effects of drugs in the brain. There is not explanation or analyses in the probable social and cultural causes and effects for using a drug.

Addiction is like all behaviours “the business of the brain”. Addictions are compulsive physical and psychological needs from habit-forming sustenances like nicotine, alcohol, and drugs. Being occupied with or involved in such activities, leads a person who uses them again and again to become tolerant and dependent eventually experiencing withdrawal. (Molintas, 2006).

“There is no such gene or genes present in an individual with addiction. Even if a person’s father or mother or both are addicts, it does not mean, children will be too. The fact is that most people get addicted due to the influence of their environment or to experience it for the first time. The addiction gene gives a false sense of confidence and paradoxically discourages others from seeking treatment.”

Substance addiction can hugely impact on a person’s thinking, functioning and behaviour. Whilst depressant drugs such as alcohol and opioids slow down your central nervous system (CNS), stimulants such as cocaine or amphetamine increase the activity of the CNS, leading to higher blood pressure, heart rate and increased alertness. Repeated abuse of the substance leads to tolerance and withdrawal, in turn this leads to the user showing signs of irrational behaviour. Another form of substance abuse is hallucinogens; they can cause powerful changes in sensory perceptions. It works by binding to the serotonin receptors, these neurons control visual information and emotions, and this can lead to various effects on the user. Neurobiology can help us understand the reasons for addiction and the effects they have on us. Groman and Jentsch (2012) discuss key issues of differentiating the causes and consequences of addiction through neuroimaging and behavioural research on monkeys, they found that the dysfunction of the dopamine