Mr Thomas Case Study

2. Can the student tell from the blood type if the student is heterozygous or homozygous? Explain. (5 points) Yes, knowing your blood type would

Later, researchers found out that there is another antigen, on red blood cells, Rh factor. When the Rh factor is not present a person is identified as Rh- and likewise if Rh is present, a person is Rh+. Thus, a person with Antigen A, and has the Rh factor is then labeled as blood type A+ (A positive). It is important to match a donor’s blood and a recipient’s blood before a transfusion to make sure the blood is compatible. If the recipient’s blood does not match the donor’s, the recipient’s blood will clot and the recipient

10. Type A: The genotype is either AA or AO. The antigens on the blood cell are A and the antibodies in the blood plasma are B.

There are four blood types found in humans. These are A blood type which has the genotype either AA or AO, B blood type which has the genotype either BB or BO, AB blood type which has the genotype AB, and O blood type which has the genotype OO. These genotypes show a combination of complete dominance and codominance. A and B traits are dominant to the recessive O trait, however, the A trait is codominant to the B trait. Each blood type codes for certain antigens. A blood codes for the A surface antigen, B blood codes for the B surface antigen, AB blood codes for both the A and B surface antigen, and O blood does not code for a surface antigen. Therefore to determine one’s blood type a test can be performed

The goal of this experiment is to determine the blood types of the samples given and to learn what interactions occurred to each blood type. Determining an individual’s blood type and how it reacts with Anti A, Anti-B, and Anti Rh serums played a crucial part in this experiment. The researcher concluded that agglutination (clumping) occurred in some of the blood samples. For example, Mr. Smith’s blood reacted with Anti-A and Anti-Rh serums (antibodies) allowing the researcher to determine the blood type is A. Mr. Jones’s blood reacted with Anti-B serum but it did not react to Anti-A or Anti Rh allowing the researcher to believe that the blood type is B. Mr. Green’s blood reacted with all serums and caused a reaction to occur resulting the blood type to be AB positive. Mr. Green’s blood also had a positive marker for Rh factor. However, Ms. Brown’s blood had no reaction at all and the researcher determined if no reaction occurred then the sample had no antigens but proved to have some antibodies, resulting in blood type to be O. The purpose of this experiment is to determine whose blood has type A, B, AB, or O.

R/s about one week ago, Thomas was admitted to Palmetto Low Country Behavioral Health Center. R/s Thomas has primary custody of Megan (13). R/s Thomas has history of drug abuse. R/s Thomas doesn’t have a place to stay.

American Association of Blood Banks (AABB), confirmed that it is possible to determine the Rh phenotypes and the probable genotypes (26 – 28), by determine the presence or absence of the five major Rh antigens (D, C, E, c, and e). Therefore the assortment of antigens detected on a person’s red cells, constitutes the person’s Rh phenotype. (Table 1-4) illustrates the prediction pattern of the probable Rh phenotypes based on the results of tests with the five principal Rh blood typing reagents.

List the hematocrits for the healthy male (sample 1) and female (sample 2) living in Boston (at sea level) and indicate whether they are normal or whether they indicate anemia or polycythemia.

An 18-year-old male college student comes to the student care center complaining of severe fatigue for the past 1–2 weeks and a sore throat for several days. On exam he has significant lymphadenopathy and a temperature of 38.1ºC (100.5º F). The patient’s serum agglutinates horse red blood cells. His peripheral blood smear is likely to show which of the following?

Mr. Smith’s blood sample reacted to the anti-A and anti-Rh serum. With this information, we can conclude that his red blood cells contained A and Rh antigens; therefore, Mr. Smith’s blood type is A positive. Mr. Jones’ blood sample only reacted to the anti-B serum. Knowing this, we can conclude that his red blood cells contained B antigens; therefore, Mr. Jones’ blood type is B negative. Mr. Green’s blood sample reacted to the anti-A, anti-B and anti-Rh serum.

Mr. Johnson and Mrs. Johnson have been married for several years. During their marriage, the couple has had three children. Mr. Johnson has recently discovered that his wife, Mrs. Johnson, has been having an affair with Mr. Wilson throughout their marriage. Thus, Mr. Johnson now questions if he is truly the biological father of the three children. My task was to use what I know about the inheritance of ABO blood types in hopes of answering the guiding question: Are all of Mr. Johnson’s kids his biological offspring.

There are four major blood groups expressed by the ABO system. All individuals and many other primates can be categorized for the ABO blood group. First, the blood group A has A antigens on the red blood cells with anti-B antibodies in the plasma blood. Second, group B has B antigens with anti-A antibodies in the plasma blood. Next, group O develops no antigens but has together anti-A and anti-B antibodies in the plasma blood. For group AB, it has both A and B antigens but no antibodies.

Thomas root took off from National Airport at 6:33 A.M. on July 20,1989. Thomas was going to Rocky Mount, North Carolina. At 8:30 A.M. Thomas radioed that he was undergoing chest pains. The Federal Aviation Administration immediately sent a rescue plane. The rescue plane discovered that Thomas was unconscious in the cockpit. After 4 hours the plane was running out of gas and in an instant the plane started to spiral down from an altitude of 10,000 feet. The rescue team were sent down to recover a dead body,but shockingly he was swimming toward them and the raft.

Blood grouping involves the use of ABO system as described by Karl Landsteiner. The grouping came into existence in the year 1900 after discovery by Nobel Prize winner Karl Landsteiner. He first discovered three blood types A, B, and O, but after two years he discovered the fourth blood group AB. This discovery led to four major types of blood that includes A, AB, B and O. The grouping depends on the presence of two chief antigens and antibodies. The two antigens responsible for blood grouping include A and B while the antibodies include anti-A and anti-B. The combination of the two antigens and antibodies thus determines the blood types. The blood type A has antigen A and antibody anti-B. The blood group B express Antigen B and antibody anti-A (Reid and Lomas, 2004). Blood group O express no antigen but possess antibodies

10 DNA-based assays targeting single-nucleotide polymorphisms (SNPs) associated with blood group antigen expression offer an alternative. 11-14 Genotyping method provide information on RBC antigens for which standardized serologic typing reagents are not available and are responsive to high-throughput testing with computerized interpretation. RBC antigen phenotypes determined by single-nucleotide polymorphism analysis was compared with serologic testing for 13 routinely tested RBC antigens. The frequency of