Multi-drug Resistant Tuberculosis in india

With the close proximity infection range TB is known for completes the remainder of the epidemiologic triangle. Overcrowded environments are the coal to the fire of this transmittable disease with outbreaks capable of occurring, infection hundreds. Common symptoms of this active form of tuberculosis include: weight loss, coughing, fatigue, fever, night sweats, chills, and loss of appetite (MayoClinic, 2014). The Mayo Clinic also states that it is believed that 2 billion (one third) of the world population is living with Latent TB (2014). This emphasizes the need for public health and community involvement in order to completely abolish this disease from our planet.

TB is still proven to be a top killer around the world, and with more cases of drug resistant TB being reported daily, the cost of treating and preventing this disease will continue to be on the rise.

Tuberculosis is a deadly disease that is now affecting our world and the people living in it in a horrible way. Due to many factors such as poverty, HIV/AIDS, and lack of health care, many third world and developing countries have been left very vulnerable to tuberculosis. It is affecting a large part of these countries and is leading them deeper into poverty and sickness. The effort to help these countries against tuberculosis has only been slightly effective against this widespread and destructive disease.

First, in the book, we read a lot about Farmer treating people in the poorer regions of the world with little money, resources, and lots of illness. In those regions, just getting proper health care is a struggle. When treating TB, the drugs can get very expensive. As Kidder describes in his book,

Tuberculosis is a disease of an infectious nature caused by a bacterium known as mycobacterium tuberculosis. The disease spreads through the air. People with the disease can spread it to susceptible people through coughing, sneezing, talking or spitting. It mainly affects the lungs and other parts such as the lymph nodes and kidneys can also be affected. The symptoms for TB are fatigue, coughing, night sweats, weight loss and fever. One third of the population of the world is affected with mycobacterium tuberculosis. The rate of infection is estimated to be one person per second. About 14 million people in the world are infected with active tuberculosis. Drug resistant TB has been recorded to be a serious public health hazard in many countries. Resistant strains have developed making it difficult to treat the disease. TB has caused millions of death mainly in people living with HIV/AIDS ADDIN EN.CITE Ginsberg19981447(Ginsberg, 1998)1447144717Ginsberg, Ann M.The Tuberculosis Epidemic: Scientific Challenges and OpportunitiesPublic Health Reports (1974-)Public Health Reports (1974-)128-13611321998Association of Schools of Public Health00333549http://www.jstor.org/stable/4598234( HYPERLINK l "_ENREF_3" o "Ginsberg, 1998 #1447" Ginsberg, 1998). The World Health Organization came up with the DOTS (Directly Observed, Therapy, Short course) strategy. The approach involves diagnosing cases and treating patients with drugs for about 6-8

Tuberculosis (TB) is an infectious killer worldwide. However, over 95% of TB deaths occur in developing countries (WHO). TB is found to be a curable disease when appropriate medications and treatment are taken. Using the biomedical system is not sufficient to eradicate TB because medical interventions will fail if social determinates aren’t taken into considerations. The biomedical system is a key component in diminishing TB because it allows for diagnosis and control. Social determinants of health play a huge role in shaping one’s health. Three main social determinants that acts as a barrier in curing and preventing TB are income, food insecurity and access to health care.

Tuberculosis, the white plague as used to be called once upon a time is still one of the deadliest bacterial killers affecting almost all parts, all corners of the globe. Though successful anti-tubercular antibiotic regimens and effective vaccine are available for decades and being used in the battle against Koch’s bacillus, Mycobacterium tuberculosis, the causative agent of this chronic multi organ granulomatous disease, our strand in the battle continuously seems to be in the losing side. Moreover the increasing prevalence of HIV-AIDS and diabetes mellitus is being proved to be providing predisposition to tuberculosis. As witnessed by the WHO, which has estimated that, in the year 2012, 8.6 million people have developed tuberculosis and 1.3 million have died of the disease including 320000 deaths of HIV-TB co-infected people (Global tuberculosis report 2013. World Health Organization; 2013). Long term antibiotic therapy and that too associated with several side effects and discomforts have diminished patient compliance with the anti-tubercular chemotherapy. This fact in turn has raised the new deadlier MDR-TB and XDR-TB strains. The whole scenario is a matter of panic and questioning the effectiveness of anti-tubercular antibiotics, immunologic efficacy of century old BCG vaccine and all other medical advents.

The social aspect looks at how TB affects the overall impact of health related quality of life. The global section looks at the barriers of governmental funds and treatment access in different developed versus developing countries. The environmental section explores the environmental conditions in where TB impacts socioeconomic factors, including income, education, housing, age, gender, and geographic distribution. The policy section explores the policy around the treatment of TB, providing distributions of policies (funding, allocative health policies and regulated health policies) and organized policymaking processes at the federal level that allow for the improvement of the health of the population.

Tuberculosis is a disease cause by a bacterium that spreads when a person infected with the virus, sneezes, coughs, or even talks and the germs make it into the air for another person to breathe. This bacterium primarily affects the lungs and prevents the proper functioning of the respiratory system. Tuberculosis continues to be a problem in the United States and the problem is even bigger in developing countries such as India where they have seen the growth of MDR-TB cases. The following annotated bibliographies include a variety of peer review journals, a CDC website and the RX for survival video, which addresses the burden of tuberculosis in different parts of the world. The bibliographies also look at the risk factors, prevalence, mortality,

Nations which have poor control of the AIDS epidemic also often have poor control of TB, effectively creating a ‘perfect storm’ of the prevalence of both diseases (Wells et al 2007). Individuals with AIDS are more susceptible to contracting TB and an environment where TB is prevalent can worsen the prognosis for individuals with TB. Developing world nations also have poor sanitation, longer wait times to see doctors due to problems of healthcare access, and other barriers which inhibit the needed speedy treatment of the disorder which can result in ineffective treatment and worsening of

A person with fully susceptible TB may develop secondary (acquired) resistance during therapy because of inadequate treatment, not taking the prescribed regimen appropriately, or using medication of low quality. Drug-resistant tuberculosis is a serious public health issue in many developing countries because its treatment is lengthy and more expensive drugs are necessary. MDR-TB is defined as resistance to the two most effective first-line Tuberculosis drugs: rifampicin and isoniazid. Extensively drug-resistant tuberculosis is also resistant to three or more of the six classes of second-line

Drug resistance has been increasing among patients infected with Mycobacterium tuberculosis. Previous miracle drugs that were used in the 1950s have now been proven useless in many cases simply because the bacteria are not susceptible to antibiotics such as isoniazid, rifampin, pyrazinamide, etc. when they are taken. This pathogen is easily transmitted through air and has the capability of attacking the respiratory system and creating fatal consequences if not treated properly. A lot of people who contribute to the antibiotic resistant statistics are those that do not take medication accordingly. Even though the bacterium may not be resistant at first, it can

For years now drug resistance is increasing and not just in one or two strands of bacteria, it is in all of them. This resistance makes treating a patient with the infection more difficult to the point where some strands require surgery. Tuberculosis is not a bacterium that you can easily remove from the body though. It takes time and medication for the tuberculosis to be eradicated from the body. The problem is with the advancements of medicine bacterium, like tuberculosis, are starting to produce resistance to not just one or two drugs here or there, but the bacteria is producing resistance for multiple drugs at one time.

Tuberculosis is among the fatal diseases that are spread through the air. It’s contagious, meaning that it spreads from one infected individual to another, and at times it spreads very fast. In addition to being contagious, the disease is an opportunist infection as it takes advantage of those with weak defense mechanism, and especially the ones with terminal diseases like HIV and AIDS. Tuberculosis is therefore among the major concerns for the World Health Organization due to its contagious nature (World Health Organization 1).

India, the second most populous country with over 1.31 billion people, has the highest burden of tuberculosis (TB) in the world, accounting for 20% of the global incidence of TB, and an even higher share of global incidence of multi–drug resistant (MDR) TB. With an estimated 2 million new cases of TB and 5, 00,000 TB-related deaths in India annually, those who got diagnosed with different forms of DR-TB were 35,385 cases but only 20,753 people started on multidrug-resistant TB (MDR-TB) treatment in 2013. The National Tuberculosis Program was launched in 1962, but suffered heavily continuing TB led mortality. Acknowledging this reality, a Revised National Tuberculosis Control Programme (RNTCP) was launched by the Government of India in 1997, however even today it does not comply with World Health Organization (WHO) recommendations.