Multiple Schlerosis Research Papers

Multiple Sclerosis (MS) is a neurologic disease that affects the Central Nervous System (CNS) through cellular immune response and the demyelination of CNS white matter (McCance et al., 2014, pp. 630–633). The initial causes of MS are unknown however, it is believed that it could possibly be due to an immune response to an initiating infection or an autoimmune response to CNS antigens on the myelin itself (Brück, 2005) (Miljković and Spasojević, 2013). MS is a result of the degradation of the myelin sheath surrounding neurons and therefore disrupts the transmission of action potentials along these cells. MS can display itself in the form of symptoms ranging from muscle weakness to trouble with sensation and coordination (NHS, 2016). The degradation of myelin leads the body to attempt to remyelinate the neurons, a process that in turn leads to the thickening of the cell by glial cells and this causes lesions to form (Chari, 2007). It is this thickening (sclerae) from which the disease gets its name. Sufferers of MS can either have a relapsing type of MS, in which there are episodes that lead to the worsening of symptoms for a period of time, or a progressive type of MS where symptoms gradually progress and worsen (McCance et al., 2014, pp. 630–633).

Multiple sclerosis is a chronic, progressive neurological disease affecting all aspects of life: physical, cognitive, emotional, and social (Abma). It is known as an autoimmune disease, Where the body’s immune system turns against the body and destroys the protective covering that surrounds nerve cells. This damage to the nerve cells causes many problems for the patient including weakness, muscle stiffness, poor coordination and balance, tingling, numbness, tremors, blurred vision, slurred speech, and memory and concentration problems (Bren)

The central nervous system is made up of the brain and spinal cord. The brain is connected to the spinal cord. The brain helps interpret information received from the spinal cord. Through the spinal cord signals are sent to the rest of body and back to the brain. Nerve cells (neurons) are found in the nervous system and they help communicate with other cells through electrical signals. Some of the nerve cells are coated with a myelin sheath. Myelinated neurons allow electrical signals to travel at a faster speed. When the myelinated part of the nerve cell is destroyed, Multiple Sclerosis (MS) can be the one to blame.

Multiple Sclerosis, commonly known as MS is an autoimmune disease of the central nervous system. Scientists have been studying MS since the 19th century. In MS, the body’s immune system produces cells and antibodies that attack myelin in your brain which is essential for the nerves in your brain and spinal cord to conduct electricity to perform its function. The attack on myelin results in vison loss, paralysis, numbness, muscle weakness, difficulty walking, stiffness, spasms, and bladder and bowel problems. MS has varying degrees of severity and affects people between the ages of 20-50, mostly women. Although there are treatments, there is no cause and cure yet.

Multiple sclerosis is an unpredictable, crippling neurological disease of the central nervous system, which affects the flow of information within the brain, and between the brain and body. The name is this disease refers to multiple areas of scarring throughout the brain and spinal cord. This scarring is a result of what happens when the body attacks itself. A substance called Myelin surrounds the nerves to help protect them (Healthline.com, 2015). Multiple Sclerosis is thought to occur in a genetically susceptible individual (although there is no evidence to show that the disease is directly inherited) influenced one or more environmental factors. MS is thought to be an autoimmune disease, however others disagree as the target of the immune

Multiple Sclerosis is an inflammatory demyelinating neurodegenerative disorder of the central nervous system that has the potential to cause significant disability in those affected through the body's immune system attacking and destroying the myelin sheaths surrounding the axons. Myelin is rich in lipids and proteins that form layers around the nerve fibers and acts as insulation and protection. This damage to the myelin in the CNS, and to the actual nerve fibers, has the potential to block the transmission of nerve signals between the brain and spinal cord and also other parts of the body. This disruption of the nerve signals produces the primary symptoms of MS which then possibly lead to secondary and tertiary symptoms stemming from these

Multiple Sclerosis is a degenerative disease that effects the Central Nervous System. Approximately 400,000 individuals are living with Multiple Sclerosis in the United States, and 2.5 million worldwide. There are an estimated 10,000 new cases annually, in the United States alone. Various factors including geography, gender, and race are significant risk factors in developing the disease. Diagnosis at early onset of symptoms is beneficial to the treatment of progression and there are numerous medications used to combat the frequency and duration of relapse symptoms caused by Multiple

Multiple Sclerosis (MS) is an autoimmune disease of the Central Nervous System, which interferes with the communication between the Central Nervous System (brain and spinal cord) and other parts of the body. The immune system attacks the myelin on the nerve fibers; resulting in damaged myelin that forms sclerosis. Overtime, many nerve fibers and myelin sheath will be damaged or even destroyed, resulting in the nerve impulse being interrupted. MS can be mild, moderate, or severe, therefore, it may cause disability as well as death. Interestingly enough, more women are affected than men. Common signs and symptoms of multiple sclerosis include: fatigue, difficulties with walking (gait), spasticity, numbness/tingling, weakness, vision problems, pain, vertigo, depression, emotional changes, cognitive changes, bladder/bowel problems, and sexual problems. Less common signs and symptoms include: speech/swallowing problems, seizures, tremor, breathing problems, headache, pruritus, and hearing loss. There a four different types of Multiple Sclerosis: Relapsing-remitting MS (RRMS), Secondary Progressive MS (SPMS), Primary-progressive MS (PPMS), and Progressive-relapsing MS (PRMS). Relapsing-remitting Multiple Sclerosis is the most common type of MS; about 85% of people are diagnosed with this type of Multiple Sclerosis. Relapsing-remitting Multiple Sclerosis is characterized by worsening neurologic function attacks throughout the disease. The attacks are also known

Multiple sclerosis (also known as MS) is an autoimmune disease which affects the spinal cord and brain (central nervous system). It is considered to be one of the most mysterious diseases because there are no exact recognition on its causes; there is no cure as well. Rather, treatment is used to prevent its attacks. The common mechanism of multiple sclerosis is the failure of myelin to produce cells because of the destruction of the immune system. Myelin is part of a neuron which helps propagation of impulses (electrical messages) of the central nervous system. It is also an essential part of the central nervous system. The United States,

Multiple Sclerosis is a chronic progressive disease involving damage to the myelin sheaths of nerve cells in the brain and spinal cord. The exact cause of multiple sclerosis is unknown but we know that something triggers the immune system to attack the central nervous system (CNS). MS happens when your immune system attacks a fatty material called myelin and without this outer shell, your nerves become damaged. The resulting damage to myelin that insulates wire like nerve fibers is a disruption of signals to and from the brain. This hiatus of communication signals causes unpredictable symptoms such as numbness, tingling, mood changes, memory problems, blindness, paralysis, fatigue and pain. People who have MS experience the disease differently,

Multiple Sclerosis (MS) is a rare disease that directly disables the central nervous system (CNS). While there has been some recent studies, there still isn’t enough research for scientist to classify the exact causes of MS. However, all researchers declare that the causation of MS is a direct impact of the disease “attacking” the central nervous system, which leads to a disruption of the flow of information within the brain, and between the brain and body (National MS Society). When there is a disturbance within the CNS, signals within the brain and from the brain to the body are altered, which can have devastating effects on patients. MS is a mysterious disease that still has a lot of research to be conducted in order for scientist and doctors

Worldwide, more than 2.3 million people are currently affected by Multiple Sclerosis (MS). This condition “is a life-long, potentially debilitating disease of the central nervous system (CNS)” (Pasquier, 2014, 537). Specifically, it is a chronic auto-immune disease that attacks the central nervous system. Furthermore, the person’s own immune system does not recognize the neurons and attacks the myelin, and the nerve fibers it covers and protects. The myelin then creates scar tissue which causes damage and keeps the nerve impulses in the neuron from being able to travel to the brain or the spinal cord. If this occurs, bodily functions become difficult or impossible because messages aren’t being delivered to or from the organs back to the CNS.

Multiple sclerosis, or MS, is a very common disease that affects more women than men; at a minimum two to three times relevant in women (Harbo, 2013). Sadly, according to the National Multiple Sclerosis Society, since 1975, there has not been a successful national study of the prevalence in the United States. In order to improve reporting MS, the National MS Society established a method of testing administrative databases. In turn, the Society reported that MS organization have estimated 2.3 million individuals are living with MS worldwide. Is it the most common disabling neurological disease affecting young adults (Courtney, 2009). The greatest number of people who are identified with the disease are between the ages of 20 to 50, even though it can still be found in younger children and notable older adults. I personally find this statistic to be alarming. I am at risk for developing this disease since I am in my mid-20s. It is important that I understand and am aware of the disease because the actual cause of the disease in still a mystery. The environment and our genes could play a role in contributing to the disease.

Multiple Sclerosis (MS) is an unpredictable immune-mediated disease where the body’s own immune system destroys the myelin sheaths of the affected individuals neurons. MS is a disabling disease because it disrupts the flow of information within the brain and the flow of information between the brain and the body. The cause of MS is unknown but it affects women more than men. Scientists believe the disease is triggered by certain environmental factors to individuals who are genetically predisposed. The antigen present in the myelin and nerve fibers that immune cells target is still unknown. Damaged myelin forms scar tissue (sclerosis). There is no cure for MS but individuals with MS seek treatment to help prevent the degradation of neurons.

Multiple Sclerosis, one of the most complex diseases ever described, impacts over 2.3 million people worldwide. All ages are affected, especially women and young adults. While MS is uncommonly inherited, it can be carried in specific gene variants. In all of its forms, MS attacks both the nervous and immune systems. Researchers haven’t been able to pinpoint exactly where the disease begins, but many believe that immune cells are sent to the nervous system where they destroy myelin. That myelin, which protects axons, is essential for sending nervous signals; when we can’t send nerve signals, our bodies are unable to detect pain, and additionally lose the ability to feel, in targeted areas. Initially, a MS victim will have trouble with everyday activities like walking, running, and vision issues, and might also experience numbness or tingling sensations in their fingers. Over time, faulty connections become more and more damaged, progressing the disease. Primary progressive MS, the most severe form, has the quickest decline in health. There are therapies and treatments available to