The nervous system is responsible for registering extrinsic and intrinsic factors and communicating them with the entirety of the body. Dendrites acquire these signals from other neurons and then the signal is transmitted through the cell body and down the axon. Graded potentials create an electrical charge that eventually leads to threshold being met and action potentials being generated. These action potentials send the signals down the axon. Signals will sometimes struggle to hike up stream due to threshold recently being met. This absolute refractory state inhibits signals from traveling up the axon unless myelin is present to increase signaling. It takes longer to conduct a signal down an un-myelinated axon because voltage-gated ion channels …show more content…
A disorder where the body is attacking itself is known as an autoimmune disorder. In an autoimmune disorder the body cannot decipher between a pathogen, bacteria, or infection attacking the body and normal healthy body tissue. The majority of autoimmune disorders are long lasting or even permanent. An example of a chronic autoimmune disorder is multiple sclerosis (MS).
Multiple Sclerosis (MS) is a condition where myelin forms scar tissue and disfigures nerve impulses. This is an example of a deviation from normal physiology found in the nervous system. MS is the result of the immune system atypically attacking myelin and nerve fibers within the central nervous system (CNS). When the myelin and nerve fiber are damaged, it can cause the signal to be disturbed or disfigured. The damaged scar tissue (sclerosis) gives the disease its name. The symptoms of MS can range anywhere from pain and fatigue to tremors and
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Sadly, there is no cure for multiple sclerosis and no way to completely restore the normal function of the nervous system. Specialists focus on trying to manage relapses in patients with relapsing forms of MS. During remissions, after relapses, the body works to repair areas that have been damaged. Negative feedback works to restore homeostasis in the CNS by releasing oligodendrocytes to start repairing demyelinated axons. Despite hard work by the CNS to restore complete myelination there are still some parts of the axon that remain unlyelinaated. These parts of the axon produce more sodium channels that open during action potentials to allow more sodium ions to flow in and play a crucial role in nerve transmission. When there are more sodium channels it allows MS patients to have remission from a
Nearly 400,000 individuals in the United States are diagnosed with multiple sclerosis (MS). Multiple sclerosis is defined as “a potentially disabling disease of the brain and spinal cord”. (Multiple) Multiple sclerosis is classified as an autoimmune disorder in which the immune system attacks an element of itself, specifically the protective sheath (myelin) that covers nerve fibers and causes problems with communication between the elements of the central nervous system and the rest of the body. Multiple sclerosis can cause nerves to deteriorate over time or permanently damaging the nerves, which causes permanent damage to the body as nerves are unable
Multiple Sclerosis (MS) is a neurologic disease that affects the Central Nervous System (CNS) through cellular immune response and the demyelination of CNS white matter (McCance et al., 2014, pp. 630–633). The initial causes of MS are unknown however, it is believed that it could possibly be due to an immune response to an initiating infection or an autoimmune response to CNS antigens on the myelin itself (Brück, 2005) (Miljković and Spasojević, 2013). MS is a result of the degradation of the myelin sheath surrounding neurons and therefore disrupts the transmission of action potentials along these cells. MS can display itself in the form of symptoms ranging from muscle weakness to trouble with sensation and coordination (NHS, 2016). The degradation of myelin leads the body to attempt to remyelinate the neurons, a process that in turn leads to the thickening of the cell by glial cells and this causes lesions to form (Chari, 2007). It is this thickening (sclerae) from which the disease gets its name. Sufferers of MS can either have a relapsing type of MS, in which there are episodes that lead to the worsening of symptoms for a period of time, or a progressive type of MS where symptoms gradually progress and worsen (McCance et al., 2014, pp. 630–633).
Multiple sclerosis is a chronic, progressive neurological disease affecting all aspects of life: physical, cognitive, emotional, and social (Abma). It is known as an autoimmune disease, Where the body’s immune system turns against the body and destroys the protective covering that surrounds nerve cells. This damage to the nerve cells causes many problems for the patient including weakness, muscle stiffness, poor coordination and balance, tingling, numbness, tremors, blurred vision, slurred speech, and memory and concentration problems (Bren)
Multiple sclerosis, or MS, is a disease of the central nervous system. The central nervous system is made up of the brain and spinal cord. Both have nerve fibers that are wrapped in a myelin sheath. In MS, the myelin sheath becomes inflamed and gradually is destroyed. With the destruction of the myelin sheath comes an array of symptoms that may include numbness or tingling, balance problems, weakness, muscle spasms, and blurred vision.
MS(Multiple Sclerosis) is a disease which gradually hardens all tissues and also causes scars. These scars form when the persons immune system's cells go into the central nervous system and cause inflammation to the brain, spinal cord and optic nerves. MS is also a non contagious and unpredictable disease. MS is also the most common chronic disease (when it comes to the CNS (Central Nervous System)) with young Australians. Throughout all the states of Australia, Victoria is the State with the most people that have the condition.
The central nervous system is made up of the brain and spinal cord. The brain is connected to the spinal cord. The brain helps interpret information received from the spinal cord. Through the spinal cord signals are sent to the rest of body and back to the brain. Nerve cells (neurons) are found in the nervous system and they help communicate with other cells through electrical signals. Some of the nerve cells are coated with a myelin sheath. Myelinated neurons allow electrical signals to travel at a faster speed. When the myelinated part of the nerve cell is destroyed, Multiple Sclerosis (MS) can be the one to blame.
Multiple Sclerosis, commonly known as MS is an autoimmune disease of the central nervous system. Scientists have been studying MS since the 19th century. In MS, the body’s immune system produces cells and antibodies that attack myelin in your brain which is essential for the nerves in your brain and spinal cord to conduct electricity to perform its function. The attack on myelin results in vison loss, paralysis, numbness, muscle weakness, difficulty walking, stiffness, spasms, and bladder and bowel problems. MS has varying degrees of severity and affects people between the ages of 20-50, mostly women. Although there are treatments, there is no cause and cure yet.
“Multiple sclerosis (MS) is a disease in which your immune system attacks the protective sheath (myelin) that covers your nerves” (Mayo Clinic). The immune system is a defensive system that protects your body from diseases and illnesses such as parasites and bacteria (Science Museum). Not only does your immune system defend the human body but also the immune system can work against the body, which is known as autoimmune disease. Since the immune system is working against your body to attack the myelin, this creates an opportunity for multiple sclerosis to invade the nerves in the central nervous system (CNS). The myelin within the body acts like insulation to protect and coat the nervous system (National Multiple Sclerosis Society). Once the myelin is eroded, the nerves become exposed which then causes signals to and from the brain to become distorted or irrupted causing a wide range of symptoms to occur (National Multiple Sclerosis Society). The effect of the myelin eroding is an irreversible process (Mayo Clinic). “The damaged myelin forms scar tissue (sclerosis), which
By attacking the myelin MS causes inflammation and damage to the myelin itself (MS Society of Canada, 2016). Myelin is the main source of transportation for nerve impulses; this is done through the nerve fibres that are protected by the myelin (MS Society of Canada, 2016). If the myelin is only slightly damaged the nerve impulses can continue with a few minor interruptions, but if the damage is extensive then problems become more apparent (MS Society of Canada, 2016).
Multiple Sclerosis, commonly referred to as MS, is an unpredictable disorder of the central nervous system, or CNS, and it is a chronic inflammatory disorder. MS is a disease that involves the immune system attacking the CNS. They myelin that covers and protects the nerve fibers is damaged, as well as the nerve fibers themselves. They myelin that is damaged forms scar tissue know as sclerosis. This is where the name of the disease came from. When the nerve fibers or myelin is damaged, the nerve fibers that travel to and from the spinal cord are distorted or interrupted this is why there is a variety of symptoms that can occur. Multiple Sclerosis affects rather young individuals, as young as twenty. It is most common in adults in their twenties
MS is an autoimmune disease, meaning the immune system attacks the bodys own myelin sheath protection. The damaged myelin and axon fibers is caused by overactivated T cells.
Multiple Sclerosis (MS) is an autoimmune disease of the Central Nervous System, which interferes with the communication between the Central Nervous System (brain and spinal cord) and other parts of the body. The immune system attacks the myelin on the nerve fibers; resulting in damaged myelin that forms sclerosis. Overtime, many nerve fibers and myelin sheath will be damaged or even destroyed, resulting in the nerve impulse being interrupted. MS can be mild, moderate, or severe, therefore, it may cause disability as well as death. Interestingly enough, more women are affected than men. Common signs and symptoms of multiple sclerosis include: fatigue, difficulties with walking (gait), spasticity, numbness/tingling, weakness, vision problems, pain, vertigo, depression, emotional changes, cognitive changes, bladder/bowel problems, and sexual problems. Less common signs and symptoms include: speech/swallowing problems, seizures, tremor, breathing problems, headache, pruritus, and hearing loss. There a four different types of Multiple Sclerosis: Relapsing-remitting MS (RRMS), Secondary Progressive MS (SPMS), Primary-progressive MS (PPMS), and Progressive-relapsing MS (PRMS). Relapsing-remitting Multiple Sclerosis is the most common type of MS; about 85% of people are diagnosed with this type of Multiple Sclerosis. Relapsing-remitting Multiple Sclerosis is characterized by worsening neurologic function attacks throughout the disease. The attacks are also known
Multiple sclerosis (MS) is a chronic, often disabling disorder, affecting the central nervous system. The symptoms of MS may be mild, such as numbness in the limbs, or severe, such as paralysis or loss of vision. The progress of symptoms and their severity are currently unpredictable and vary from individual to individual. To date, the new treatments available and the progress of science are giving new hope to people affected by this First you need to specify the characteristics of this disease. In multiple sclerosis we are witnessing an immune system attack against the central nervous system.
Imagine a world where you have been diagnosed with a disease that has no cure and left your world upside down because your body has turned against you. Multiple Sclerosis is a potentially debilitating disease that is caused by the body’s immune system attacking the Myelin sheath of nerve fibers throughout the body (Multiple Sclerosis, 2017). This, in turn, creates miscommunication or lack of communication in the body, which can eventually lead to permanent disability. For those who are diagnosed, there are various symptoms to watch for and while not curable, it is treatable.
Multiple sclerosis (MS) is an acquired demyelinating disease of the central nervous system (CNS) that typically is diagnosed in the second or third decade of life. Normally, nerves are enclosed in myelin sheaths that help facilitate transmission of nerve impulses within the CNS and the peripheral nervous system throughout the body. In patients with MS, the myelin sheath is damaged and eventually degenerates, causing patches of scar tissue called plaques or lesions to occur anywhere randomly on the myelin sheath (Ruto, 2013). This results in impaired nerve conductivity, which interferes with message transmission between the brain and the other parts of the body. As a result, impulse transmission is altered, distorted, short-circuited, or completely absent. This interference in impulse transmission creates muscle weakness, muscle imbalance, and possibly muscle spasms with partial or complete paralysis. Multiple sclerosis also can result in visual impairment and alteration of cognitive abilities, as well as pain, numbness, or tingling sensations (Ruto, 2013).