Multiple Sclerosis Report

Multiple Sclerosis (MS) is a neurologic disease that affects the Central Nervous System (CNS) through cellular immune response and the demyelination of CNS white matter (McCance et al., 2014, pp. 630–633). The initial causes of MS are unknown however, it is believed that it could possibly be due to an immune response to an initiating infection or an autoimmune response to CNS antigens on the myelin itself (Brück, 2005) (Miljković and Spasojević, 2013). MS is a result of the degradation of the myelin sheath surrounding neurons and therefore disrupts the transmission of action potentials along these cells. MS can display itself in the form of symptoms ranging from muscle weakness to trouble with sensation and coordination (NHS, 2016). The degradation of myelin leads the body to attempt to remyelinate the neurons, a process that in turn leads to the thickening of the cell by glial cells and this causes lesions to form (Chari, 2007). It is this thickening (sclerae) from which the disease gets its name. Sufferers of MS can either have a relapsing type of MS, in which there are episodes that lead to the worsening of symptoms for a period of time, or a progressive type of MS where symptoms gradually progress and worsen (McCance et al., 2014, pp. 630–633).

Multiple sclerosis is a chronic, progressive neurological disease affecting all aspects of life: physical, cognitive, emotional, and social (Abma). It is known as an autoimmune disease, Where the body’s immune system turns against the body and destroys the protective covering that surrounds nerve cells. This damage to the nerve cells causes many problems for the patient including weakness, muscle stiffness, poor coordination and balance, tingling, numbness, tremors, blurred vision, slurred speech, and memory and concentration problems (Bren)

Multiple Sclerosis (MS) is a chronic inflammatory disease of the central nervous system. MS affects approximately 3.0 million people globally, with about 300,000 cases in the United States. Twice as many women as men have MS. The average ages for onset of MS is 20-40 years. In MS, cells in the immune system attack and destroy myelin, the fatty tissue surrounding nerve cells (http://www.phylomed.com/MS.html). Scar tissue replaces the myelin, interfering with the transmission of nerve signals and leading to numbness, fatigue, spasticity, loss of muscle control, and various other debilitating symptoms. There are four broad theories

MS(Multiple Sclerosis) is a disease which gradually hardens all tissues and also causes scars. These scars form when the persons immune system's cells go into the central nervous system and cause inflammation to the brain, spinal cord and optic nerves. MS is also a non contagious and unpredictable disease. MS is also the most common chronic disease (when it comes to the CNS (Central Nervous System)) with young Australians. Throughout all the states of Australia, Victoria is the State with the most people that have the condition.

The central nervous system is made up of the brain and spinal cord. The brain is connected to the spinal cord. The brain helps interpret information received from the spinal cord. Through the spinal cord signals are sent to the rest of body and back to the brain. Nerve cells (neurons) are found in the nervous system and they help communicate with other cells through electrical signals. Some of the nerve cells are coated with a myelin sheath. Myelinated neurons allow electrical signals to travel at a faster speed. When the myelinated part of the nerve cell is destroyed, Multiple Sclerosis (MS) can be the one to blame.

Multiple sclerosis is characterized by inflammation, demyelination, and axonal damage in the brain and spinal cord with a loss of myelin that covers the axons. As the myelin sheath regenerates, scar tissue forms, which looks like plaques on magnetic resonance imaging scans. Multiple sclerosis arises when immune-mediated inflammation activates T cells and causes the T cells and immune mediators to cross the blood-brain barriers into the CNS and attack oligodendrocytes (ie, a type of neuroglial cell with dendritic projections that coil around axons of neural cells). When the oligodendrocytes are attacked, the myelin sheath is replaced by scar tissue, which forms throughout the CNS. As a result of damage to the myelin sheath, the ability to transmit and conduct nerve impulses along the spinal cord and in the brain is interrupted, leading to muscle weakness, fatigue, loss of coordination, balance impairment, and cognitive and visual disturbance (DeLuca & Nocentini, 2011). This disease is characterized by unpredictable remissions that occur over several years. During periods of remission, the myelin sheath usually regenerates and symptoms may resolve, but the myelin cannot be completely repaired. As the disease progresses, the myelin sheath is destroyed and nerve impulses become much slower or absent and symptoms worsen. When degeneration exceeds self-repair ability, permanent disability results. There are four defined clinical types of

Multiple Sclerosis, commonly known as MS is an autoimmune disease of the central nervous system. Scientists have been studying MS since the 19th century. In MS, the body’s immune system produces cells and antibodies that attack myelin in your brain which is essential for the nerves in your brain and spinal cord to conduct electricity to perform its function. The attack on myelin results in vison loss, paralysis, numbness, muscle weakness, difficulty walking, stiffness, spasms, and bladder and bowel problems. MS has varying degrees of severity and affects people between the ages of 20-50, mostly women. Although there are treatments, there is no cause and cure yet.

“Multiple sclerosis (MS) is a disease in which your immune system attacks the protective sheath (myelin) that covers your nerves” (Mayo Clinic). The immune system is a defensive system that protects your body from diseases and illnesses such as parasites and bacteria (Science Museum). Not only does your immune system defend the human body but also the immune system can work against the body, which is known as autoimmune disease. Since the immune system is working against your body to attack the myelin, this creates an opportunity for multiple sclerosis to invade the nerves in the central nervous system (CNS). The myelin within the body acts like insulation to protect and coat the nervous system (National Multiple Sclerosis Society). Once the myelin is eroded, the nerves become exposed which then causes signals to and from the brain to become distorted or irrupted causing a wide range of symptoms to occur (National Multiple Sclerosis Society). The effect of the myelin eroding is an irreversible process (Mayo Clinic). “The damaged myelin forms scar tissue (sclerosis), which

Multiple sclerosis is an unpredictable, crippling neurological disease of the central nervous system, which affects the flow of information within the brain, and between the brain and body. The name is this disease refers to multiple areas of scarring throughout the brain and spinal cord. This scarring is a result of what happens when the body attacks itself. A substance called Myelin surrounds the nerves to help protect them (Healthline.com, 2015). Multiple Sclerosis is thought to occur in a genetically susceptible individual (although there is no evidence to show that the disease is directly inherited) influenced one or more environmental factors. MS is thought to be an autoimmune disease, however others disagree as the target of the immune

Multiple Sclerosis is an inflammatory demyelinating neurodegenerative disorder of the central nervous system that has the potential to cause significant disability in those affected through the body's immune system attacking and destroying the myelin sheaths surrounding the axons. Myelin is rich in lipids and proteins that form layers around the nerve fibers and acts as insulation and protection. This damage to the myelin in the CNS, and to the actual nerve fibers, has the potential to block the transmission of nerve signals between the brain and spinal cord and also other parts of the body. This disruption of the nerve signals produces the primary symptoms of MS which then possibly lead to secondary and tertiary symptoms stemming from these

Multiple sclerosis is a disease that affects the central nervous system, attacking the brain and the spinal cord. MS attacks myelin, the fatty material that acts as a protective coating to the body's nerves. (1) The inflammation of the nerve tissues covering the nerves can affect any part of the nervous system and varies from person to person. (7) Normal nerve function decreases with the onset of MS because MS causes scars to form on

Multiple Sclerosis, also known as “MS” is a chronic condition where the immune system begins to destroy the myelin sheath that covers the nerves in the body and affects the brain and spinal cord (Mayo Clinic Staff, 2014). The myelin sheath is used for protection of the nerves in which these nerves aid to transport nerve impulses all over the body (Ruto, 2013). Once the body’s immune system attacks the myelin sheath, it begins to disintegrate which affects the conductivity of the nerve impulse and impedes the message transmission from the brain to the rest of the body (Ruto, 2013). In turn, the impulses are changed which results in problems in the muscle such as weakness, imbalance and spasms and the body could end up

Multiple Sclerosis is an autoimmune disorder where the myelin sheath within the Central Nervous System is attacked (National Multiple Sclerosis Society, 2017). The myelin sheath protects the axon of the nerve cell. When the myelin sheath is intact, the axon is able to carry impulses away from the neuron’s cell body, and the message carried is clear. With Multiple Sclerosis, the myelin sheath becomes scarred, hence the word “sclerosis”, and distorts the nerve impulses traveling over the CNS (National Multiple Sclerosis Society, 2017). This may cause the message to be changed or stopped altogether.

Multiple sclerosis (MS) is a disease of the Central nervous system that progresses over a period time (“NINDS,” 2015). The central nervous system (CNS) includes the brain, spinal cord, and peripheral nerves. Damage to the central nervous system may interfere with sensory, motor, and cognitive functions. Myelin is an insulating layer around neuron processes that serves as a protective barrier (“MedlinePlus,”2016). In the case of Multiple Sclerosis, this protective layer is permanently damaged by sources that is still being investigated. The deterioration of the Myelin sheath inhibits, or slows down signals between the brain and the body (“NMSS,” 2012). Although there is currently no cure for Multiple Sclerosis, there are different treatment options that may help slow down the progression of the disease. As a chronic disease, it offers many challenges to the researchers looking for holistic ways to manage symptoms.

Multiple sclerosis (MS) is a degenerative and potentially debilitating disorder that affects the spinal cord and brain, collectively known as the central nervous system. Multiple sclerosis evolves gradually throughout time and is considered to be auto-immune, which means the immune system mistakenly attacks healthy cells and tissues that are supposed to be within the body. According to Medscape, symptoms consist of, but are not limited to, sexual problems, ataxia (the inability to control certain muscle movements as defined by Tortora and Derrickson), fatigue, and optic neuritis. Multiple sclerosis is characterized into four different types: relapsing-remitting MS, secondary-progressive MS, primary-progressive MS, and progressive-relapsing MS. There is currently no cure for multiple sclerosis, but there are many forms of treatments to help suppress the symptoms and hinder the progression. The Patient Education Institute lists of treatments include prescription medication and healthy lifestyle habits, such as exercising. Steroids are also administered to delay the severity of the attacks. The aforementioned details about the treatments, types, and symptoms of multiple sclerosis are merely a superficial analysis. To fully understand this disease, a more in-depth and detailed focus of its impact within the body is needed.