Multiple Sclerosis Research Papers

Multiple sclerosis (MS) involves an autoimmune process that develops when a previous viral insult to the nervous system has occurred in a genetically susceptible individual. B lymphocytes, plasma cells, and activated T cells, along with proinflammatory cytokines, cause inflammation, oligodendrocyte injury and demyelination. Early inflammation and demyelination lead to irreversible axonal

Nearly 400,000 individuals in the United States are diagnosed with multiple sclerosis (MS). Multiple sclerosis is defined as “a potentially disabling disease of the brain and spinal cord”. (Multiple) Multiple sclerosis is classified as an autoimmune disorder in which the immune system attacks an element of itself, specifically the protective sheath (myelin) that covers nerve fibers and causes problems with communication between the elements of the central nervous system and the rest of the body. Multiple sclerosis can cause nerves to deteriorate over time or permanently damaging the nerves, which causes permanent damage to the body as nerves are unable

MS is characterized by the destruction of myelin, inflammation in the CNS and the formation of lesions in the CNS.

Multiple sclerosis, or MS, is a disease of the central nervous system. The central nervous system is made up of the brain and spinal cord. Both have nerve fibers that are wrapped in a myelin sheath. In MS, the myelin sheath becomes inflamed and gradually is destroyed. With the destruction of the myelin sheath comes an array of symptoms that may include numbness or tingling, balance problems, weakness, muscle spasms, and blurred vision.

Multiple Sclerosis, commonly known as MS is an autoimmune disease of the central nervous system. Scientists have been studying MS since the 19th century. In MS, the body’s immune system produces cells and antibodies that attack myelin in your brain which is essential for the nerves in your brain and spinal cord to conduct electricity to perform its function. The attack on myelin results in vison loss, paralysis, numbness, muscle weakness, difficulty walking, stiffness, spasms, and bladder and bowel problems. MS has varying degrees of severity and affects people between the ages of 20-50, mostly women. Although there are treatments, there is no cause and cure yet.

Multiple sclerosis is an unpredictable, crippling neurological disease of the central nervous system, which affects the flow of information within the brain, and between the brain and body. The name is this disease refers to multiple areas of scarring throughout the brain and spinal cord. This scarring is a result of what happens when the body attacks itself. A substance called Myelin surrounds the nerves to help protect them (Healthline.com, 2015). Multiple Sclerosis is thought to occur in a genetically susceptible individual (although there is no evidence to show that the disease is directly inherited) influenced one or more environmental factors. MS is thought to be an autoimmune disease, however others disagree as the target of the immune

Multiple sclerosis, also known as MS, is an autoimmune and inflammatory disease that is very painful for both the patient and care giver. In the disease, there is inflammation and neurodegeneration acting at the same time. There is currently no known primary cause of multiple sclerosis. The disease is however characterized by damaged fatty myelin sheaths around the axons of the brain and the spinal cord. Myelin is a mixture of proteins and phospholipids that protects many nerve fibers enabling speed at which impulses are conducted. It is pathologically characterized as the presence of glial scars all over in the central nervous system. The disease was discovered by the French neurologist Jean-Martin Charcot in 1868 when he examined the brain

Multiple sclerosis (MS) is a chronic, often disabling disorder, affecting the central nervous system. The symptoms of MS may be mild, such as numbness in the limbs, or severe, such as paralysis or loss of vision. The progress of symptoms and their severity are currently unpredictable and vary from individual to individual. To date, the new treatments available and the progress of science are giving new hope to people affected by this First you need to specify the characteristics of this disease. In multiple sclerosis we are witnessing an immune system attack against the central nervous system.

Multiple Sclerosis (MS). In the United States alone, approximately 200 new cases of MS are

There is no cure for Multiple Sclerosis (Mayo Clinic, 2017). Most treatment is focused on improving quality of life by treating symptoms and slowing its progression. There are a few drugs to help slow progression, most of which are for relapsing-remitting MS (Mayo Clinic, 2017). In March of this year, the FDA approved the first drug for primary-progressive MS (FDA, 2017), called ocrelizumab, which slows the advancement of disability (Mayo Clinic, 2017). Ocrelizumab may cause infusion related reactions, such as hives, shortness of breath, fever, etc, and may lead to an upper respiratory tract infection (FDA, 2017). Acute relapses are treated with corticosteroids to reduce nerve inflammation, a traditional and approved method of treatment. (NIH, 2013). To treat symptoms, those with MS may go to physical therapy to help strengthen muscles and manage gait problems (Mayo Clinic, 2017). They may also use muscle relaxers to treat extremely painful

Multiple Sclerosis (MS), is considered to be "a immune-mediated disease" (nationalmssociety.org). This means within the Central Nervous System (CNS), the immune system mistakenly attacks myelin – The "fatty substance that surrounds and insulates the nerve fibers" (nationalmssociety.org) – as well as nerve fibers themselves. When the myelin and nerve fibers are damaged, the myelin interferes with nerve conduction. The symptoms of MS relate to this interruption of signaling between

Multiple sclerosis (MS) is an acquired demyelinating disease of the central nervous system (CNS) that typically is diagnosed in the second or third decade of life. Normally, nerves are enclosed in myelin sheaths that help facilitate transmission of nerve impulses within the CNS and the peripheral nervous system throughout the body. In patients with MS, the myelin sheath is damaged and eventually degenerates, causing patches of scar tissue called plaques or lesions to occur anywhere randomly on the myelin sheath (Ruto, 2013). This results in impaired nerve conductivity, which interferes with message transmission between the brain and the other parts of the body. As a result, impulse transmission is altered, distorted, short-circuited, or completely absent. This interference in impulse transmission creates muscle weakness, muscle imbalance, and possibly muscle spasms with partial or complete paralysis. Multiple sclerosis also can result in visual impairment and alteration of cognitive abilities, as well as pain, numbness, or tingling sensations (Ruto, 2013).

Multiple sclerosis is a progressive disease that affects the central nervous system, which includes but is not limited to the brain, spinal cord, and optic nerves. Within the CNS the immune system attacks myelin sheaths, which are fatty membranes surrounding the axon of a neuron. Overtime the damaged myelin sheath forms scar tissue called sclerosis, which is what gives the disease its name. When scleroses are formed on the myelin sheath, nerve impulses that travel to and from the brain and spinal cord are dramatically slowed and sometimes even completely blocked. Consequently the muscular system is not able to function properly, which is what gives MS such crippling symptoms.

Imagine waking up one morning realizing that it could be the last day to live? People who are diagnosed with Multiple Sclerosis can relate to that. Multiple Sclerosis also known as MS is a disease located in the central nervous system in which the nerves gradually lose their protective covering of myelin(Frey 737). Myelin is a fatty substance that insulates the nerves and allows them to transmit messages to and from the brain(Frey 737). There are four different types of MS. However the most common type people get is called Relapsing Remitting Multiple Sclerosis (MSHC). The patient who has this form will have occasional attacks (also called relapses) in which symptoms get worse. Followed by periods of remission in which the patient has stable health(Frey 737). As of today there is still no cause for MS, although there are several theories still being tested( Jacoby 1140; HDC 1131 ). Multiple Sclerosis is a deadly disease, but we can stop this disorder with your help to find a cure.

2013). It makes sense that most of these issues are because of a lack of having control