As previously mentioned, WPHs are pre-digested to a degree, meaning that the resulting amino acids are more quickly distributed to skeletal muscles. This positively impacts the rate of rate of muscle protein synthesis after exercise. The way this process works is broken into two main steps – transcription and translation (Editors, 2011). In transcription, DNA is “unzipped” (opened), and with the help of the enzyme RNA polymerase, messenger RNA, or mRNA, is created by pairing complementary nucleotides using the DNA as an “instructional template”. This step does not require amino acids, but is necessary to briefly mention in order to give context to the second step. Translation involves the mRNA binding to ribosomes in the cytoplasm of the muscle cell. Here, transfer RNA, or tRNA, molecules also bind to the ribosome. The order …show more content…
First of all, WPHs are effective scavengers of molecules with free radicals in the body (Tang et al, 2012) due to their hydrophobicity. Secondly, reducing power is significant in WPHs, so that when these free radicals are found, they are eliminated effectively. In cells, oxygen is needed for many processes, but there are side effects of frequent exposure to the molecule, namely the formation of free radicals. These highly reactive molecules have an unpaired electron, allowing them to interact freely with and do damage to lipid molecules, particularly ones with double bonds. Since cell membranes have a high lipid content, they are at risk without antioxidant protection. Tang et al (2012) showed that WPHs from peanut peptides effectively scavenge and reduce hydroxyl radicals (most dangerous) and 2, 2-diphenyl-1-picrylhydrazyl (DPPH) radicals. The latter of the two is particularly notable, as “The model of scavenging stable DPPH radical is a widely used method to evaluate antioxidant activities in a relatively short time compared with other methods.” (p.
Translation is a task that makes ribosomes synthesize proteins utilizing mRNA transcript made during transcription. In the begining of this task mRNA attaches it self to a ribosome so that it can be reveal a codon (three nucleotides).
3) As a ribosome moves along the mRNA, the genetic message is translated into a protein with a specific amino acid sequence.
Transcription is the formation of an RNA strand from a DNA template within the nucleus of a cell. There are four nucleotides of DNA. These are adenine, cytosine, guanine and thymine. These nucleotides are transcribed to form messenger ribonucleic acid (mRNA) consisting of nucleotides made of adenine, cytosine, guanine and uracil. This transcription from DNA to mRNA happens by an RNA polymerase II. This newly created mRNA is read in the 5' to 3' direction in sets of 3. These sets are called codons. Each mRNA also has a cap and end. On the 5 prime side is a methylated guanine triphosphate and on the 3 prime is a poly A tail. Messenger RNA then moves to the cells cytoplasm and through the cells ribosomes for translation. Messenger RNA is matched to molecules of transfer RNA (tRNA) in the ribosomes to create amino acids. These amino acids subsequently form an amino acid chain. (Osuri, 2003) A visual representation of this can been viewed in figure 3.
The small ribosomal subunit, amongst other things, is initiates the engagement of the mRNA and is responsible decoding the genetic information during translation [4].
ZMA is a combination of Zinc, Magnessium and Vitamin B6. It plays a role as a Testosterone Supporting agent and is involved in ablout 500 metabolic reactions in our body. Besides increasing Testosterone, ZMA also increases the performance level and strength.
After the DNA has been turned into mRNA a process called translation occurs and it turns the mRNA into tRNA.
The biological value in whey protein enhances the body’s ability to absorb essential amino acids after resistance training decreasing the athlete’s recovery time. When athletes combine whey protein and creatine monohydrate they expect “a greater increase in lean tissue mass and muscular strength than supplementations with whey protein alone” (Burke, Chilibeck, Davison, Candow, Farthing, & Smith-Palmer 2001, p 350). Exogenous Cr supplementation increases the body’s Cr levels until saturation occurs. This saturation of Cr increases the PCK shuttle continuum allowing training intensity, volume, and duration of the exercise the athlete is performing to continue at a maximum rate. Any excess Cr in the blood is cleared through sweat, urination or renal filtration. Measurements in strength and peak torques of athletes supplementing with whey protein and creatine monohydrate (WC), whey protein (W), and a placebo (P) were taken. According to Burke et al, (2001) “repeated measure analysis of variance was used to assess changes in body composition, strength, and peak torque for the three groups (WC vs. W vs. P) across time” (p. 354). A twelve week strength training program was constructed and consisted of a “4-day split routine involving whole body musculature” (Burke et al, 2001. p 352). Subjects used detailed training logs to compare progress over the 12 week experiment. The end result from this experiment shows that subjects who “supplemented with both creatine and whey
To build muscles, you need protein. To build muscles, you must maintain a sufficient amount of protein. Your body alone does not produce enough protein and that's why we need to find other sources, such as a high protein diet or a protein supplement, to provide the protein our body needs. Proteins will create body heat and speed up your metabolism. As a result, protein affects your metabolism which is more than fat or carbohydrates. This explains why the muscle mass is stronger than the fat. Exercise will change the metabolism of a person's protein. The amount of exercise a person does is fully understood by any protein provided by his
The next question that needs to be asked is what happens to protein after exercise. In the previous section, it was discussed that there is protein synthesis and protein breakdown and it is controlled by glycogen. In a review article Tipton and Wolfe (2001), explain there are three factors that play a role in protein synthesis: type of exercise performed, intensity, and condition. The goal of training is to get better so understanding the best way to stimulate protein synthesis is important. In resistance training, this is important because protein helps rebuild the
Your body is in a constant battle against infection, diseases and the formation of free radicals. However, there's a secret weapon that can help you fight against these things: antioxidants! Antioxidants are elements such as vitamins A, C and E that counteract the damage caused by free radicals and help protect your healthy cells. Free radicals are the molecules that contain unpaired electrons, which make them highly reactive. In this form, they can cause damage by attacking healthy cells, and when these cells grow weakened, you become more vulnerable to disease.
The subunits of ribosomes target and bind to mRNA. Ribosomes then link amino acids together based on the mRNA template. They do this by pairing the codons of the mRNA
The nucleus creates mRNA and the mRNA goes through the nuclear pores into the cytoplasm. The mRNA is transcribed the from the DNA. Once the mRNA enters the cytoplasm it is translated by ribosomes, than the corresponding amino acids come and form proteins.
The formation of a protein begins in the genes, which contain the basic building information for all parts of living organisms. There are four DNA nucleotides that make up genes: A, T, C, and G. A codon is any arrangement of three of these nucleotides. Each triplet of nucleotides codes for one amino acid. First transcription will begin in the nucleus where mRNA will transcribe the DNA template. During both transcription and translation, there are three steps. The first step in transcription is initiation where RNA polymerase separates a DNA strand and binds RNA nucleotides to the DNA. RNA nucleotides are the same as DNA ones except that U replaces the T. The second is just the elongation of the mRNA. The third step of transcription is termination. This occurs when RNA polymerase reads a codon region and the mRNA separates from the
Increase the glucose uptake by cell membrane of the skeletal muscle cells and fat cells, increased protein synthesis
Protein Synthesis Protein Synthesis is the process whereby DNA (deoxyribonucleic acid) codes for the production of essential proteins, such as enzymes and hormones. Proteins are long chains of molecules called amino acids. Different proteins are made by using different sequences and varying numbers of amino acids. The smallest protein consists of fifty amino acids and the largest is about three thousand amino acids long. Protein synthesis occurs on ribosomes in the cytoplasm of a cell but is controlled by DNA located in the nucleus.