Myasthenia Gravis: It's Diagonosis and Treatment Essay

The most common features of Neuromyotonia is muscle stiffness, muscles contracting, twitching muscles (myokymia), and weakened reflexes. These symptoms can be designated to a particular area, usually the face and hands or throughout the body. Stiffness is mostly featured in the limbs and trunk muscles. Observable symptoms include abnormal movements, pains and cramps. Behavioral changes include disruptive sleep, excessive sweating, although these types of symptoms are uncommon. Symptoms can occur during sleep and when under anesthesia. Muscle fiber excessive activity can lead to muscle weakness or increase size of muscle cells known as hypertrophy (David, Firth, Cox 515). Being diagnose with Neuromyonia ranges from a wide age range fifthteen to sixty, most people experience signs before their forties (Maddison 2119).

Periodic Paralysis Syndrome is a blanket term for a couple of inherited muscular disorders. The most common types are hypokalemic periodic paralysis and hyperkalemic periodic paralysis. Both of these are inherited and generally present from childhood, tho it is possible for symptoms to start showing later in adolescence. In hyperkalemic periodic paralysis, high levels of potassium in the blood interact with genetically caused abnormalities in sodium channels (pores that allow the passage of sodium molecules) in muscle cells, resulting in temporary muscle weakness and, when severe, in temporary paralysis. This disease may be caused by genetic defects in either the calcium channel or the sodium channel. Hypokalemic disease may be caused by genetic defects in either the calcium channel or the sodium channel (Medline Plus).

It happens when your nerve endings fail to interact properly with your muscles. MG usually affects the muscles of the eyes, face, neck, arms, and legs. MG is most common in young women 20 to 30 years of age, and in men 60 to 70 years of age.(Myasthenia) What makes this relevant is that Myasthenia Gravis can be developed in the human body if you are exposed to neurotoxins like Sarin. On base by the Syrian border, sirens were triggered daily and the officials at the base said that they were false alarms even though they knew that they were not. “A woman named Tracy Elledge, a former combat engineer and one of the veterans I interviewed, said, “Alarms went off all the time.… Our officers told us they were false and to disconnect

3. Describe what would happen to the resting membrane potential if the sodium-potassium transport pump was blocked.

Myasthenia Gravis (MG) is a chronic autoimmune disorder of the neuromuscular system part of the body. Chronic means persisting for a long time or constantly recurring. Autoimmune disorder is the confusion of the body’s immune system. The immune system form antibodies that mistakenly identify healthy tissue as foreign and then, the antibodies will attack and/or destroy healthy body tissue. Neuromuscular is the nervous system relationship with the muscles bring about body movement.

Myofascial pain syndrome, otherwise known as MPS, is a chronic pain disorder. The word myofascial broken apart means muscle, and muscle tissue, and fascia which is the membrane supporting muscles. In the condition of MPS, pressure on sensitive points in the muscles, also known as trigger points, cause pain in the muscle. Sometimes the trigger points also send pain to other parts of your body that seem unrelated to the tense muscle, known as referred pain. Myofascial pain syndrome typically occurs after a muscle has been contracted repetitively. Although everyone experiences muscle tension and pain, the discomfort associated with MPS will persist and worsen over time.

Myalgia or muscle discomfort is incredibly common for beginner athletes and people who work out with heavy equipment, due to the fact the most widespread causes for the condition is overuse or over-stretching of muscles. Muscle pains can cause severe discomfort and are typically the reason why people lose the determination to work out or even do anything beyond moderate physical activity. This is due to the fact that by the time you recover from myalgia, you'd have already lost that inital excitement in the thought of obtaining good health.

When a membrane is excited depolarization begins. When the membrane depolarizes the resting membrane potential of -70 mV becomes less negative. When the membrane potential reaches 0 mV, indicating there is no charge difference across the membrane. the sodium ion channels start to close and potassium ion channels open. By the time the sodium ion channels finally close. The membrane potential has reached +35 mV. The opening of the potassium channels allows K+ to flow out of the cell down its electrochemical gradient ( ion of like charge are repelled from each other). The flow of K+ out of the cell causes the membrane potential to move in a negative direction. This is referred to as repolarization. ( Marieb & Mitchell, 2009). As the transmembrane potential comes back down towards its resting potential level and the potassium channels begins to close, the trasmembrane potential level goes just below -90mV, causing a brief period of hyperpolarization (Martini, Nath & Bartholomew, 2012). Finally, as the potassium channels close, the membrane turns back to its resting potential until it is excited or inhibited again.

myasthenia Gravis is caused by a breakdown in the normal communication between nerves and muscles. Muscle weakness which is caused by myasthenia gravis worsens as the affected muscle is used repeatedly.

Muscular dystrophy is a lethal sex-linked disorder characterised by progressive muscle weakness and muscle degeneration. It has been a medical problem for many years. In particularly Duchenne muscular dystrophy (DMD) for it is the most frequently occurring and one of the most rapidly progressive in children neuromuscular disorders (MDA, 2015). DMD affects approximately 1 in 3600 live male births throughout the whole world (MDA, 2015). DMD can cause or create an array of difficulties for diagnosed patients depending on how bad the patient’s case of DMD is. This is all as a result of the faulty or lack of the dystrophin gene, making it incredibly difficult for these patients to do simple activities like walking and running.

The majority of neurons, at least within the central nervous system, contain both AMPA and NMDA receptors. Under normal conditions, the NMDA receptor is blocked by a magnesium ion,

Myasthenia gravis is considered an autoimmune disease because people who have it carry an antibody called polyclonal that destroys the acetylcholine receptors (Neurology, 2013). These antibodies destroy receptor sites in the neuromuscular junction faster than the body can produce them. Usually antibodies protect the body from foreign invaders like bacteria and viruses, but in the case of MG it attacks accessories that are required for muscle movement. In a study conducted by Jon Lindstrom and Seybold Marjorie (1998), it was concluded that out of 71 patients with MG, 87 percent of them had a greater amount of antibodies for destroying acetlycholine receptors than normal (Lindstrom & Marjorie, 1998). They compared this amount to 175 patients

systems affects muscle movement and pain, temperature, and touch sensations. GBS is more common in adult males

Myasthenia gravis is a disease that affects voluntary muscles of the body; it causes the weakening of the muscles. In this essay we will talk about how to treat myasthenia gravis, the symptoms and causes

Hence, this would allow for an influx of sodium into the cell down its electrochemical gradient. It would also allow for the flow of potassium outward, as it has a 140mM concentration inside the cell and wants to shift down its concentration gradient to 5.4mM. Therefore, this great driving force for the influx of sodium and efflux of potassium helps to explain the findings at this point. As Table 1 shows, the findings within this figure are statistically supported. The fact that there is not significant difference between the findings of this experiment and the calculated Nernst at the 10, 20 and 40mM of potassium is an indicator that sodium is the largest determinant of the resting membrane potential. However, some findings defy the expectations, as the last two concentrations elicit a resting membrane potential significantly more negative than expected. This can be explained by the fact that at this point, each muscle at their respective muscle groups has been protruded many