Mycobacterium Tuberculosis An Overwhelming Pathogen.

1272 WordsApr 10, 20176 Pages
Mycobacterium Tuberculosis an Overwhelming Pathogen Alejandro Pinon Miami Dade College Author Notes Contact: alexpinon1992@hotmail.com Abstract Mycobacterium tuberculosis is one of the most overwhelming pathogens that to the day is known for produce annually around 2-3 million casualties worldwide.…show more content…
The resistance of the organism towards the host immune response and its ability to survive and reactivate at a later stage is poorly understood. An obligate aerobe, M. tuberculosis resides within alveolar mononuclear phagocytes and is thought to use a variety of redox systems to protect itself against the oxidative intermediates generated by the macrophages (Shinnick et al., 1995). An important fact to have in mind is that the thyroid system can also aid in the regeneration of inactivated proteins caused by the oxidative stress. Mycobacterium tuberculosis is uses the method of spread by small airborne droplets, which is called called droplet nuclei. It is produced by the coughing, sneezing, talking, or singing of a person with pulmonary or laryngeal tuberculosis (Nawrath et al.,2012). Hence, is frequently spread through aerosolizing of the bacterium. The foremost infection route of the bacterium is through the lungs; nonetheless, invasion of mucous membranes or breaks in the skin are also possible. Direct person to person transmission of M. tuberculosis occurs through exposure to airborne bacilli in the sputum of infected persons. Medical personnel are at risk of infection during autopsies, intubation, bronchoscopies or through dermal inoculation. Tuberculosis is is not a disease that

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