Naloxone Research Paper

This rise in opioid abuse and overdose, warrants an increase in awareness. Over the years reversal agents have been developed and others are still under investigation. The most commonly used opioid reversal agent in the US is naloxone. Many organizations are reporting an increase in the number

Narcan may enable addicts, but with it commercially available, the heroin epidemic will be likely to decline. This wonder drug isn’t just for heroin and opioid abuse, though, anyone who takes an opioid drug such as morphine or codeine is at risk of an overdose(The Opioid Crisis). Accidental overdose is just as dangerous as heroin when it comes to these prescription drugs, so having Narcan available could save their life(Padilla). With 47,000 opioid deaths, 61% of those deaths could of have been saved with Narcan in the household (Kounang). In Conclusion, Narcan has the potential to save thousands of lives yearly, but with the cost and the false sense of security, is it worth

Last year there were over 64,000 reported opioid-related deaths in the United States – making it the leading cause of accidental death in people under the age of 50 in this country (Katz). Opioids, also referred to as painkillers, have become a growing problem over the past two decades particularly in rural communities all across the country where the death rates are higher per capita compared to the death rate in cities (“America’s Opioid Epidemic is Worsening”). These narcotics, such as codeine, fentanyl, hydrocodone, morphine and oxycodone are extremely addictive and, as a result, this silent killer has quadrupled the overdose death toll since 1999

Opioid drugs are some of the most widespread pain medications that we have in this country; indeed, the fact is that opioid analgesic prescriptions have increased by over 300% from 1999 to 2010 (Mitch 989). Consequently, the number of deaths from overdose increased from 4000 to 16,600 a year in the same time frame (Mitch 989). This fact becomes even more frightening when you think about today; the annual number of fatal drug overdoses in the Unites States now surpasses that of motor vehicle deaths (Alexander 1865). Even worse, overdose deaths caused by opioids specifically exceed those attributed to both cocaine and heroin combined (Alexander 1865).

Naloxone is an opioid antagonist that is designed to rapidly reverse opioid overdose. Take home naloxone programs aim to reduce overdose fatalities by training community members as first responders to opioid overdoses. Opioid users are provided with naloxone

However, this step isn't necessarily to cure the epidemic, but rather to keep it from becoming more catastrophic. This drug is not to be used as away of getting people to stop using opioids in anyway, but rather just keep them from dieing when they do use opioids. Then those who have overdosed can go get help from the types of programs previously mentioned. This is the most important step because it needs to be put into action immediately. If this step takes as long as predicted then the epidemic will only be getting worse and far too many lives will be taken away yet again by opioids. Although, “While DuPage County is the only county currently using intranasal naloxone, Kane, Lake, McHenry and Will Counties are set to implement plans to use both forms of naloxone in the coming months” (Kirk launches suburban anti-heroin task force 1 death every 3 days on average since 2012; using narcan during an overdose was 100% effective in Dupage County, States News

The United States currently faces an unprecedented epidemic of opioid addiction. This includes painkillers, heroin, and other drugs made from the same base chemical. In the couple of years, approximately one out of twenty Americans reported misuse or abuse of prescriptions painkillers. Heroin abuse and overdoses are on the rise and are the leading cause of injury deaths, surpassing car accidents and gun shots. The current problem differs from the opioid addiction outbreaks of the past in that it is also predominant in the middle and affluent classes. Ultimately, anyone can be fighting a battle with addiction and it is important for family members and loved ones to know the signs. The cause for this epidemic is that the current spike of opioid abuse can be traced to two decades of increased prescription rates for painkillers by well-meaning physicians.

Once more, the lives of Canadians are being claimed by addiction and overdose of a new drug in the streets. For those of you who don’t know what fentanyl is, it’s a powerful opioid, 100 times stronger than morphine, that is often prescribed to help patients manage moderate to severe pain. As a highly addictive substance, many are now dependent on it, and it is one of the most frequent causes of drug overdose. Readily available for purchase online are quantities of pure fentanyl from China, but when improperly diluted in clandestine labs, it can lead to an immediate overdose. Recently, an antidote for opioid overdose called naloxone has become available without prescription, so that anyone can use it. Fentanyl has become a severe problem in the past few years, and while we yet to find a way to eliminate dependence on this drug, we must keep those who use it safe.

Nevertheless, several studies have shown that intranasal Naloxone absorbs in the same amount of time as intravenous Naloxone when the administrator accounts for the time Naloxone takes for an I.V. to be placed. Granted the absorption rate is slower for intranasal admission versus intravenous, the nasal route still has a valuable blood supply allowing Naloxone to be absorbed efficiently (Robison and Wermeling 2131). Intranasal administration is effective enough to reverse drug overdose. Intranasal administration can be repeated every three minutes and last for 180 minutes while intravenous Naloxone

Today, Naloxone is now being prescribed and dispensed to people at risk of opioid overdose. The number of overdose deaths has quadrupled since 1999. Statistics show that increased availability, relatively low price (compared to prescription opioids), and high purity of heroin in the United States is one of the reasons why death rates are so high. From 2000 to 2015, more than half a million people died from drug overdoses. Every day, approximately 91 Americans die from an opioid overdose. It is a proven fact that most people who are addicted suffer the most overdoses. Anyone taking drugs can suffer an opiate overdose, especially when they take more than prescribed or if they combine opiates with other CNS (Central Nervous System) depressants with alcohol. It's rare for someone to die immediately from an overdose, it's usually a very slow process that takes anywhere from a few minutes to a few hours. After you administer the Naloxone, it lasts between 30-90 minutes before the overdose begins to recur. Also, Naloxone can also cause an uncomfortable withdrawal feeling; This is because it blocks the action of opioids in the

Narcan is an opioid antagonist that reverses the effects of prescription pain medications and heroin. When victims are suffering from an overdose police officers simply spray Narcan up their nose. Within 2-6 minutes the victim should start to breathe again. For some families, giving their son or daughter another chance at life means everything to them while other families feel it is pointless. Many people feel that if all law enforcement is equipped to carry Narcan then drug users will feel they are invincible. Drug addicts don’t use drugs to get to the point of overdose only to be

Naloxone, also known as Narcan, is the life-saving drug. It is what is given to people who have overdosed on heroin or another opioid as an antidote. According to Roosevelt University, it

Naltrexone is an FDA-approved non-opioid medication to prevent relapse after opioids have been completely eliminated from the body. Unlike, methadone and buprenorphine, it has no addiction potential.

Naloxone is a drug that can reverse the effects of an opioid overdose. In the past this drug was only available with a prescription from a medical official. But thanks to Governor Kasich and an emergency legislation, this drug is now available over the counter. Now it can be acquired without a prescription. Now loved ones of an abuser can administer the drug to an addict without being in fear of breaking the law and being charged with a crime. Now other states have been following a similar road, passing similar legislatures. John Kasich has inspired other states to join his fight against opioid abuse.

Classified as an antidote, naloxone gives individuals who overdose on opioids a second chance at life, but without access to proper treatment, these users will continue living in the cycle of addiction until either finding enough strength to pull through the recovery process or falling victim to life’s only certainty prematurely.