Narrow-Spectrum Drugs vs. Broad-Spectrum Drugs
By: Tyranny Williams
Narrow-spectrum drugs are effective against a select few kind of pathogens. The advantages of these kind of drugs include:
- The drug treatment will only deal with eliminating one specific bacteria that is causing an individual to have an infection.
- The narrow-spectrum drug will not kill as many normal/ beneficial microorganisms in the body system than a broad-spectrum drug.
- Bacteria are less likely to form a resistance against the drug.
The only disadvantage of using these kinds of drugs is that these drugs can be used if the cause of an infection is known; if the right narrow-spectrum drug is not chosen then there is a chance that the infection will persist because the
Health experts know that most antibiotic products interfere with the immune system and the digestive system. Most of these products quell probiotic bacteria
If the patient reaches the third stage, the antibiotics may not work. During the time of the bubonic plague and the Black Death they didn’t have antidote to be treated with. Antibiotics did
Most drug lists have at least three or four tiers of drugs. The tier determines
Section 3 of the Promise for Antibiotics and Therapeutics for Health Act or the PATH Act, which call for current PATH Act legislation to be modified so that it “will allow health experts to more easily develop new treatments for antibiotic resistant bacteria, and make real progress in presenting a great number of illnesses and deaths in the United States”1. In addition, this new legislation will impact Section 506 of the Federal Food, Drug, and Cosmetic Act (21 U.S.C 356) by introducing into its current language a new subsection (g) “Limited Population Pathway for Antibacterial Drugs”. Thus creating new avenues for the introduction of alternative treatments for limited populations based on the recommendation of Secretary
When there is disagreement amongst clinicians about categorization, refer to additional literature to reach a consensus
Hart was the differences in antibiotics. Different medications have different mechanisms of action, which determines which microorganisms they can treat. Dr. Hart spent time explaining some of the different antibiotics and their uses in treatment.
In order for the “magic bullet” to effectively target all sorts of microbes, including gram positive/negative, acid fast, viruses, parasites and fungi, it would need to be broad spectrum. By allowing it to be broad spectrum it will target various forms of microbes, not just one type. Target sites would include cell wall, metabolic, cytoplasm membrane and nucleic acid inhibition. Protein synthesis inhibition will not be used, for the risk that it might affect 70s ribosomes within the mitochondria of eukaryotic cells. This medication would be taken orally so a wide number of patients can use.
Drugs are used in these cases but the results are not always fortunate. Though the vast majority of drugs are used to treat medical conditions, there are also the few
All this type of medication have the similar action at the cellular level they inhibit intercellular calcium ion influx.
Sometimes medicines are not needed if the case isn’t serious. If the infection needs serious attention, doctors will first cut or drain the infected area and then determine if there is any bacterial resistance to antibiotics. If the bacteria is resistant to any type of antibiotic then the doctor will not prescribe any to the patient.
In the last decade, the number of prescriptions for antibiotics has increases. Even though, antibiotics are helpful, an excess amount of antibiotics can be dangerous. Quite often antibiotics are wrongly prescribed to cure viruses when they are meant to target bacteria. Antibiotics are a type of medicine that is prone to kill microorganisms, or bacteria. By examining the PBS documentary Hunting the Nightmare Bacteria and the article “U.S. government taps GlaxoSmithKline for New Antibiotics” by Ben Hirschler as well as a few other articles can help depict the problem that is of doctors prescribing antibiotics wrongly or excessively, which can led to becoming harmful to the body.
Stop using antibiotics to cure infections that are caused by viruses. Antibiotics attack and kill bacterial micro-organisms, not viruses (e.g. cold, flu).
be less likely to be infected by the virus(Carson-DeWitt). Antibiotics are only given to the patient if
The assessment of bioequivalence as a tool for evaluating the safety and efficacy is based on the fundamental Bioequivalence Assumption that if two drug products are shown to be bioequivalent in average bioavailability, it is assumed they will reach the same therapeutic effect and be used interchangeably [1].