Necrotic Plague: A Case Study

In the year 1348 the world changed forever. The Black Death, which is another name for the Bubonic Plague, laid havoc on the entire world. “The plague chases the screaming without pity and does not accept a treasure for a ransom. Its engine is far-reaching. The plague enters into the house and swears it will not leave except with all of its inhabitants…” (Al-Wardi, #29, 113). The plague did not care if the people were rich, poor, white, black, Muslim or Catholic, it would kill whomever it could. The plague brought out the worst in people because people acted selfishly, people were completely inhumane, and there was no peace.

Some species have been isolated in the stomach, gallbladder, intestine, vagina, and skin of healthy persons. The bacteria produce toxins that dissolve cell membranes, causing death of muscle cells, massive spreading edema, hemolysis of red blood cells, hemolytic anemia, hemoglobinuria, and renal failure. Characteristic of this disorder are the bubbles of hydrogen sulfide gas that form in the muscle. Gas gangrene is a serious and potentially fatal disease. Antibiotics are used to treat the infection and surgical methods are used to remove the infected tissue. Amputation may be required to prevent spreading (Porth & Gaspard,

The Black Death, also known as the bubonic plague, was a disease that devastated Medieval Europe, between 1346 and 1352 it killed 45 million people, wiping out a third of Europe's population. Today, we know that there were many causes of the Black Death. Medieval towns had no system of drains, sewers or trash collections. In such slovenly conditions, germs could grow, and diseased rats could call these medieval towns their homes and infect the people who lived there. Many historians believed the plague originated in china and spread to other countries by trade routes. Infected people and/or infected rodents such as mice or black rats. The Black Death was caused by strains of the bubonic plague. The plague lived in fleas, and fleas lived on

The roots of this fearsome plague are very chilling to think about knowing that a mere flea can be the cause of the bubonic plagues epidemic. The more specific medical or scientific term for this disease is Yersinia Pestis. This was named after the doctor, Alexandre Yersin, who isolated the bacteria in 1894 during the pandemic that began in China in the 1860’s. The earliest traces of Y Pestis can be found all the way back to the Gobi Desert of Mongolia in the 1320’s. The cause of the sudden eruption is yet to be solved but the earliest major toll it has taken in our history books is in China in the 1330’s during the expansion of trade in the middle and high

What is the plague? The plague or referred to as the Black Death, according to the CDC (2015), “is a disease that affects humans and other mammals and caused by the Yersinia pestis bacteria. Humans usually get plague after being bitten by a rodent flea that is carrying the plague bacterium or by handling an animal infected with plague”. There are three categories of a plague. There is the bubonic plague, which is the most common form. With this form bacteria infects the lymph system and causes it to become inflamed. Symptoms of this type of plague are fever, headache, chills, and swollen and tender lymph nodes, which are called buboes. Then there is the Septicemic, which occurs when the bacteria multiply in the blood. Symptoms of this type of plague are fever, chills, extreme weakness, abdominal pain, shock, and possibly bleeding into the skin and other organs. Also, skin and other tissues may turn black and die, especially fingers, toes and the nose (CDC, 2015). Then there is the Pneumonic Plague, which is the most serious form of plague and occurs when Y. pestis bacteria infect the lungs and cause pneumonia (NIH, 2015). This is the only form of the plague that can be transmitted human to human. Symptoms of this form of the plague are ever, headache, weakness, and a rapidly

It is when the fleas jump to human hosts that the disease is spread. The strain of bacteria was not officially known until 1894 when it was identified as Yersinia Pestis. ?? -2 Yersinia pestis attacks and disables human’s immune systems and then starts multiplying within the body. Yersinia pestis is a very irregular bacteria that acquired its genetic makeup from other bacteria and viruses.

The causes of the Black Death – the flea, the rat, and the bacillus Yersinia pestis– have been labeled the “unholy trinity” (Boeckl). The flea is able to live in environmental conditions of about 74° Fahrenheit and 60% humidity (Ibid). Before the Black Death reached Europe, they were experiencing those same types of weather conditions. The rat flea, Xenopsylla cheopis and the human flea, Pulex irritans, are both capable of transmitting plague (Boeckl). Sometimes, an infected flea cannot ingest blood because Yersinia pestis obstructs its digestive tract. The blockage causes a flea to regurgitate into a bitten host rather than ingest the host’s blood, thereby infecting the host with plague (Boeckl). Unable to eat, the famished flea will bite with more frequency, accelerating the spread of plague. A flea can be carrying Yersinia pestis without it blocking the flea’s digestive tract, in which case the flea does not transmit plague when it bites a host. Also, Yersinia pestis can only enter a victim through a bite, as the bacilli cannot pass through intact skin (Gottfried).

The Bubonic Plague was likely the first semi-global pandemic that rightfully merits the name which means affecting all people. The period of time in which the disease wreaked havoc was also known as the “Black Death." Alexandere Yersin was a French bacteriologist and discovered the bacteria in Hong Kong This diabolical disease is characterized by both positive and negative outcomes for the few people that managed to survive the plague. The total number of people who died subsequently of the disease are not known. The total number of deaths ranged from twenty to fifty million people. Many, grotesque, unpleasant characteristics are associated with the Black plague. Scientists now understand that the Black Death was spread by a bacillus known as Yersina Pestis. The dominant carrier of the disease was the "black" rat. Other rodents located in central Asia could have also contributed to the disease spreading. A French biologist discovered the germ during the nineteenth century. Recently Dr. Jahannes Krause has been able to do some "molecular fishing" and extract the remaining plague fragments, and DNA from the tooth enamel of excavated remains from the 1300 's. There are three types of the infection. The manifest through buboes (boils) with unpleasant smelling odors, and spots on the skin. Swollen, inflamed lymph nodes in the armpits and groin would appear. The lymphatic system is a major contributing factor to one 's immune system and general health condition.

It primarily infected insects and animals like rats and fleas of which both spend more of their time in filthy areas. The fleas infected with Yersinia Pestis bit the rats and the rats bit the humans. The bacteria gets into the bloodstream of the human and moves towards all the lymph nodes, then quickly migrate to the brain, liver, and spleen, completely destroying the organs inside and out. The disease also spread further pneumatically, the passing of the disease from person to person through coughs and sneezes, so many people tried their best to avoid big crowd of people

The “Black Plague” is a term applied to an infectious disease that is caused by a gram negative organism called “Yersinia pestis”. Rodents ,such as rats, squirrels, rabbits, cats, mice etc., are the main source of origin for this bacteria, the bacteria itself being spread between animals by their fleas. The bacillus has been prevalent in wild rodents in the continents of Europe and Asia for many centuries, and the disease has, at times, devastated inhabitants and influenced the course of history. Major outbreaks in the human population mainly result from exposure to rats that are infected. While there is only one bacteria causes plague, it can affect people in three different forms: Bubonic, a form characterized by swelling of the lymph

plague in and of itself is a bacterium called yersinia pestis and is carried by rodents (Scogna).

The Plague (French, La Peste) is a novel written by Albert Camus that is about an epidemic of bubonic plague. The Plague is set in a small Mediterranean town in North Africa called Oran. Dr. Bernard Rieux, one of the main characters, describes it as an ugly town. Oran’s inhabitants are boring people who appear to live, for the most part, habitual lives. The main focus of the town is money. “…everyone is bored, and devotes himself to cultivating habits. Our citizens work hard, but solely with the object of getting rich. Their chief interest is in commerce, and their chief aim in life is, as they call it, 'doing business’” (Camus 4). The citizens’ unawareness of life’s riches and pleasures show their susceptibility to the oncoming plague.

As a result of their study, rat fleas, also known as Xenopsylla cheopis, are identified to be the main source of transmission of the bubonic plague. The bubonic plague is a disease of rodents, in which bacterial pathogen, Yersinia Pestis, is spread by the infected fleas (Duncan and Scott 2005, 316). Black rats generally like living in close proximity with human populations. Consequently, these rodents create a high risk of spreading the plague with close contact in human environments such as homes, mills, barns and even the same room as its human host. When black rats and humans share the same environment, it creates a breeding ground for the development of an epidemic of bubonic

The symptoms of Ebola are a fever, headache, joint and muscle aches, vomiting, stomach pain, sore throat, diarrhea, weakness and occasionally read eyes, rashes, hiccups, and internal and external bleeding and since these symptoms are not specific to Ebola, it is difficult to clinically diagnose and can often be confused with other viruses. The ELISA testing, short for enzyme-linked immunosorbent assay, and virus isolation are a couple of examples of the types of laboratory testing that can be done to diagnose and Ebola patient. Because of how easily it can be transmitted, it is extremely difficult to treat and there is no approved, official treatment. As of now, there is not standard treatment but usually the patients are given fluids and oxygen, have their blood pressure monitored and other necessary treatment. To prevent transmission and spreading the virus, the doctors use extreme caution and wear head to toe protective gear and isolate the patient. Even though the Ebola virus is common in Africa, there has been no known outbreak in the United States. Another difficulty facing scientists and the treatment for Ebola is that the natural reservoir for the virus unknown. The natural reservoir of a virus is it’s long term host of the

Ebola then spreads through direct contact with blood or other bodily fluids. Caregivers can contract this disease by coming in contact with blood, vomit, or other fluid. Ebola patients bleed intensely, so the chances of a caregiver contracting it is high. Also, many caregivers use rituals that require bathing the bodies, making them more vulnerable to infection. The disease is spreading from small, isolated villages to large cities, where it will be much harder to isolate patients.