Neovascular Age-Related Eye Disease Study

Macular Degeneration is a disease of the eye that gradually causes loss of a person’s central vision. Approximately 1.75 million Americans suffer from vision loss associated with the disease (All About Vision 1). The leading cause of blindness in people over the age of 60, Macular Degeneration, exists in two types (National Eye Institute 1). Both the wet and dry versions of the disease have similarities in risk factors, but differ in symptoms and treatments.

The research topic I will be introducing is Age-Related Macular Degeneration. This has been classified as a degenerative disorder that distresses the macula in one’s eye. AMD is unfortunately a common illness that individuals over 65 suffer from and that is a central cause vision loss. AMD doesn’t have a set disease pathway, in some individuals it advances slowly so that loss of vision does not arise for a long time. The disease can also advance much quicker and may lead to lack of vision in either or both eyes. The disease begins a blurry area near the center of one’s vision which grows larger and larger possibly causing a blank space in the eye (Boyd, 2013). Research is being done on AMD because it is a prevalent illness and has extreme consequences.

Important to realize, blindness affects many people. Disabilities such as glaucoma, cataracts, age-related macular degeneration, diabetic retinopathy, meningitis, and women who are pregnant with syphilis are at risk of developing blindness (Marcovitz 10). Many children in less developed countries live with vitamin A deficiencies which can lead to blindness (“Blindness”). Researchers

In this article, "EyeSee: Carrot naturalactives concentrate for eye health from Diana", Phillipe Saroner states "The maintenance of normal function of the eye is strongly dependent on the consumption of the antioxidant nutrients including hydrophobic carotids which must be transported in the blood"(22). Saroner discusses how maintaining our visual acuity throughout our life is a major concern of the entire population, and improving visual comfort has a significant impact on our quality of life. As a result, The intake of essential and specific nutrients ensuring the proper functioning of the eye has to be provided permanently in a practical way to easily complete the variations in nutritional intake of our diets. This source is helpful because

Age-related macular degeneration (AMD) is the leading cause of blindness for people 60 years of age and older in the developed world. Vision loss is caused by the destruction of the cone photoreceptors, located in the macula, that are responsible for color/central vision. The underlying cause of AMD is the loss of the monolayer of pigmented epithelial cells located just below the photoreceptors, known as the retinal pigmentum epithelium (RPE). The main role of the RPE is to maintain the function of the photoreceptor layer by secreting nutrients, absorbing stray light, and recycling debris used during the visual cycle. As a person ages the efficiency of the RPE layer is diminished causing a build up of toxic by-products. These toxic build-ups, known as drusens, result in the separation and death of the photoreceptor and RPE layers. AMD is speculated to result from as many as 20 different genetic mutations and as a result there is no known cure for the disease (CITE), but recent advances in stem cell therapy is a hopeful step in the right direction.

For the health condition description of age-related macular degeneration I will discuss the etiology, onset, prevalence rate, body systems, body structures, and associated deficits that come and are associated with this disease. “AMD is the degradation of the cells at the center of the retina which is the layer of tissue at the back of the eye that registers light. The macula is responsible for ventral vision, which enables us to read, drive, participate in sports, and do anything else that requires focusing directly ahead. Macular degeneration distorts the heart of the vision field” (Macular degeneration, 1998). Sunlight and smoking are both influences of the onset of AMD (Age-related Macular Degeneration (AMD), 2014). It is suggested to avoid intense bright sunlight which may help reduce the retinal degeneration. Hats, sunglasses and any other accessories that can help protect the eyes from the sun are suggested. Cigarette smoking has also been linked to increasing the risk of developing AMD and it is recommended that persons should stop smoking to decrease their chance of developing AMD (Age-related Macular Degeneration (AMD), 2014). AMD does not develop until the sixth or seventh decade of life, although early

Age related macular degeneration is a loss of function of the macula, it is more commonly known as AMD. AMD is the most common cause for vision loss in adult s over the age of 55. The macula, located in the central part of the eye, is what is being damaged. This part of the eye is what enables us to see substances that are directly in front of the field of vision.

Macular Degeneration is a disease that affects the retina of the eye. The retina is a layer in the back of the eye that helps us to see. It is also the lining of the eye that helps us respond to light. However, when having macular degeneration there are major changes in a person's central vision. The disease causes central images to appear blurred and then dark spots may begin to appear that get larger and larger. It may also be very hard to see straight lines as Macular Degeneration may cause them to be curved. When having this disease color may appear to be darker and less vivid than normal.

Retinal vein occlusion is the second leading cause of vascular disorder after diabetic retinopathy.1 Retinal vein occlusions are classified into 3 categories depending on the location of the thrombus formation; branch retinal vein occlusion (BRVO), central retinal vein occlusion (CRVO), and hemi retinal vein occlusion (Hemi-RVO). 7 BRVO is considered to be the most common among the retinal vein occlusions.6 BRVO occurs more often in men than women. Asians (5.7 per 1000) and Hispanics (6.9 per 1000) are at greater risk of developing BRVO than other ethnicities.6 The age range of patients diagnosed with retinal vein occlusion ranges from young as 14 years of age to old as 92 years of age, with 51% of patients being older than 65 years.3 Advancing age is an important risk factor for developing retinal vein occlusions. Prevalence of retinal vein occlusions in 40-49 years old is 1.57 per 1,000, 4.58 per 1,000 in 50-59 years old, 11.11 per 1,000 in 60-69 years old, 12.76 per 1,000 in 70-79 years old, and 10.32 per 1,000 in those older than 80 years.6

Carts are loaded with Vitamin A, or beta carotene, which is an antioxidant that reduces the risk of cataracts and macular degeneration. Vitamin A plays a critical role on protecting the eye surface and mucous membranes, which act as barriers to bacteria and viruses. As a result, Vitamin A reduces the risk of eye infections, and

As humans, we don't always see with our eyes, but often with our imagination (Grunwald, 2016). Often times as people we never realize how useful our vision really is to us. You really don't think about something like that until it would actual happen to you. Throughout this essay, you will learn how the body is affected by Macular Degeneration (MD). Different signs and symptoms, as well as the etiology of MD, will be discussed. In the following, diagnosis tests and treatments may also be listed in order to help others who would like to know more about MD. Not to mention, you will learn the incidence and progression of MD. Furthermore, information though agencies and associations, as well as new research about MD will be given.

Eyes are considered one of, or the most important of the five senses and one that is taken with huge appreciation, but many are unaware of the certain risk factors that are performed daily which can influence the quality of vision in the long term. According to the According to the Centers for disease control and prevention (2013) in the United States, the most common eye disorders are age related and can lead to reduction in vision or complete blindness; they include: age-related macular degeneration, diabetic retinopathy, glaucoma and cataracts. Smoking is commonly known to cause certain cancers and heart diseases, but not commonly associated with its effect on the visual system and its link to the development of these common conditions. According to Rennie et al. (2012) ‘forty-seven percent knew of the link between smoking and eye disease’. To try and promote the influence cigarettes have on the visual system, the Royal national institute for blind people (2011) has suggested including pictures and a helpline number on each cigarette packet to deter the smokers. Moreover, one of the many side effects of smoking is that it raises blood pressure. Therefore, alongside recommendations to refrain from smoking to prevent an increase in pressure, there are certain nutrients that are known to decrease blood pressure. These can prove to be a very effective treatment for ocular diseases linked to diabetes such as diabetic retinopathy and glaucoma. Despite the harmful effects of

Impact of dry eye syndrome on vision – related quality of life. American Journal of Ophthamology (March 2007)

Raeder, Steen, Vollset, and Bjelland’s (2006) experimental study demonstrated that subjects who regularly consumed cod liver oil, rich in omega-3, were 30% less likely to develop depressive symptoms; however a causal link could not be made. A recent clinical trial discovered that omega-3 might improve mood in already depressed individuals (Hallahan, Hibbeln, Davis, & Garland, 2007). The trial reported that omega-3 supplementation achieved substantial reductions in surrogate markers of suicidal behaviours and increases in wellbeing.

Zhang, Z., Wang, J., Chen, S., & Lu, W. (2014). Comparison of vegetarian diets and omnivorous diets on plasma level of HDL-c: A meta-analysis. PLoS ONE 9(3). Retrieved from: