Neurological Disorder : Parkinson 's Disease

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Neurological Disorder: Parkinson’s Disease One of the most commonly seen neurological disorders is Parkinson’s disease (PD). Named after the doctor who first identified the disease as “the shaking palsy” Dr James Parkinson (1755-1824), Parkinson’s disease affects over 1 million Americans today. On average around 60,000 Americans are diagnosed with Parkinson’s disease annually. This is an alarming number of new cases but what is even more startling is the fact that thousands of cases go undetected each year as well. PD is a clinical diagnosis with no definitive diagnostic test to identify the disease. The question may arise, what exactly is Parkinson’s disease? Parkinson’s disease is a progressive degenerative neurological disorder, which means that it gets worse over time. PD is more common with increasing age affecting 1% of the population above 55, with 4-10% of cases having early onset before the age of 40 (XXXX). The average age of onset ranges between 58-62 years old and is more common in men than women. The disease itself is defined by the presence of lewy bodies in neurons and a loss of dopamine. Degenerative changes to the basal ganglia affect the nerve cells in the substantia niagra that produce dopamine. This results in a decrease in the production of dopamine that is getting to the brain. Dopamine is a neurotransmitter involved with regulating movement making early signs of PD primarily motor impairments and progression of this disease can range from
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