Neuropathic Pain Case Study

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Many clinical conditions require bone or tissue regeneration and current therapeutic options (pharmacotherapy, neurosurgical lesioning, and anesthetic blocks) do not provide effective long-term relief associated with the accompanied neuropathic pain. Regenerative therapy uses a patient’s own tissues to initiate the healing process. Two regenerative treatments currently being offered are stem cell and platelet-rich plasma therapy. The use of adult stem cells for bone and tissue regeneration has gained much focus. This unique population of pluripotent cells has been isolated from various sources including bone marrow, adipose, and muscle cells. Genetic engineering of adult stem cells with osteogenic genes has led to rapid bone union and…show more content…
2015). The goal of regenerative medicine is to restore function through therapy at levels such as the gene, cell, tissue, or organ. For stem cells, physicians will obtain a patient’s own stem cells by aspirating tissue from the patient’s hip bone or from their fat cells. These cells are centrifuged down to identify and separate specific primitive cells that will help heal tissues (Alessandri et al., 2004). For PRP, a patient’s own blood is used and centrifuged down to obtain healing growth factors and the platelets (Pantou et al., 2012). These are rich in protein to help stimulate healing. Once these products are obtained, doctors are able to re-introduce them into the patient’s injured tissues. Regeneration of tissues and ligaments have accomplished significant improvement in patient outcomes without surgical intervention.
Stem Cells Stem cells are unique cells that have self-renewing properties and are able to differentiate into one or many different specialized cell types. Pluripotent stem cells are generally abundant in embryonic or fetal tissues, but the use of discarded embryos as sources of these cells raises many ethical problems. Thus, adult stem cells are commonly used because they can differentiate into a wider variety of cell types: bone marrow, adipose tissue, and skin tissue cells (Alessandri et al., 2004). The use of adult stem cells has resulted in several advantages including a low
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