Neurotransmitters Are Chemicals, That Are Released Into

The short term physiological effects of cocaine include constricted blood vessels, dilated pupils, and increased temperature, heart rate, and blood pressure. Large amounts intensify the user’s high, but may also lead to bizarre, erratic, and violent behavior. The short term effects on the brain are tremors, vertigo, muscle twitches, paranoia. Some users of cocaine report feelings of restlessness, irritability, and anxiety

Cocaine is one of the oldest, most powerful and most dangerous stimulants in the world. This powerfully addictive drug effects over 35 million people In the United States. Cocaine addiction prevents a person from being a productive member in our society. It also increases the cost for law enforcement and treatment facilities. It rapidly decreases the workplace, increases the homeless rate and needless deaths on a daily basis.

The short term effects of the crack includes: higher breathing rate, elevated blood pressure, soaring heart rate, compressed blood vessels, lack of appetite, dilated pupils, extreme euphoria for both casual and heavy users. The long term effects are the following: depression, violent, fearful performances, hallucinations, bad temper, psychosis, heart attack/stroke, sterility (for both men and women), brain convulsion, respiratory malfunction and even death for heavy users! Since crack cocaine is exceedingly addictive, addicts can easily build up tolerance and become addicted in a short time by smoking it constantly. There are many ways to take crack cocaine. Users can smoke through a hand pipe or a water pipe, snort, infuse through vein, or they can combine crack with marijuana, heroin etc (University Of Maryland). While taking crack, users face plenty of risks like: coughing, respiratory bleeding, out of breath, paranoia, lung trauma and many more (“Crack cocaine facts”). Dealers shipped crack cocaine from the Bahamas and the Caribbean to Miami, where the dealers would sell it for lower incomes (“A Complete History of Crack Cocaine”). Anyone can be addicted to crack cocaine – from adults to teens. Crack cocaine is most rampant in urban regions but addicts from rural areas can also be seen. Crack is highly addictive because a user trying for the first time becomes addicted to it and he uses it many times throughout the day. A single dosage is inexpensive but a crack

Neurotransmitters send messages to different parts of the body that trigger certain behaviors. For example, acetylcholine is a neurotransmitter that has an effect on movement by being released to muscle cell receptors that cause muscles to contract. Researchers have found that the brain produces its own opiates and therefore certain drugs can trigger them. The problem with this is that the brain begins to rely on those drugs and stops producing their own natural opiates. This can cause struggle and lead to addiction. Certain drugs alter neurotransmitters by either mimicking or blocking them. Agonist molecules can bind to a similar neurotransmitter to mimic and enhance its effects, while antagonists bind to neurotransmitters but block its

For short-term use, cocaine can provide extreme happiness, enhanced sensitivity to sound and touch or mental alertness. People takes cocaine as it can provide energy on their work but a long-term use of cocaine may lead to malnourishment, irritability, restlessness, paranoia and auditory hallucination (NIDA, 2016; Roncero, C., et al., 2013). Also, cocaine abuse may have other complications such as nosebleed because of snorting, difficulties in swallowing and easily infected by HIV or hepatitis C through needle injection and the misjudgment on having unsafe sex (NIDA, 2016). On the other hand, long-term use of cocaine may lead to addiction and a stronger dosage will be taken when they have any withdrawal symptoms. For instance, symptoms of depression, fatigue and increased appetite. Nowadays, still no medicines were approved for treating the addiction on cocaine and thus the treatment of cocaine addiction is

One of the most detrimental and addictive narcotics in the world today is cocaine. Cocaine dates back as early as 3000 BC. Ancient Incas used the coca leaves to counter the effects of living in thin mountain air. Native Peruvians in the 1500’s chewed the plant strictly for religious ceremonies. Andean Indians are believed to chew the leaves of the coca plant to increase their energy for work while decreasing their hunger and pain. It wasn’t until 1859 when a German chemist Albert Niemann successfully extracted the narcotic from the coca leaf. In the 1880’s, it was freely prescribed by physicians for “maladies as exhaustion, depression, and morphine addiction and was available in many patent medicines” (“Cocaine”), until users and doctors began to realize its dangers and side effects. While it was not fully understood at the time, cocaine has many devastating and lasting effects on the user.

Cocaine’s primary effect on the brain is to produce “psychoactive and addictive effects primarily by acting on the brain’s limbic system, a set of interconnected regions that regulate pleasure and motivation. Initial, short- term effect- a buildup of the neurochemical, dopamine which gives rise to euphoria and a desire to take the drug again”(Nestler, 2005, p.4). This is normally seen in some individuals that draw in the drug like through inhaling. It gives them an instant increase in blood, and brain levels. It causes the individual to become addicted to this substance. Cocaine is thought to produce pleasure/reward like any addicted drug

Most people usually think of the brain or heart being the most important part of our body. While they are indeed important, they would be entirely useless if certain substances called neurotransmitters didn’t exist. Neurotransmitters are substances in our body that carry signals from one nerve cell to another. Without these neurotransmitters in our body, we wouldn’t receive crucial signals such as telling our heart to beat. Six of the most common neurotransmitters in our body are dopamine, serotonin, endorphins, norepinephrine, acetylcholine, and gamma-aminobutyric acid (GABA).

A neurotransmitter is a chemical messenger that travels across the synapse between a neuron and another neuron, muscle fiber, or gland. Hormone is a chemical messenger of the endocrine system that is released by a gland or organ and travels through the blood. Neurotransmitter and hormone both compare because they both are chemical messenger, both chemicals are released from vessels into the surrounding fluid by similar mechanisms. They both work by binding to receptors on target cells. Neurotransmitter and hormones are very important systems, which regulate the various activities of the body, and are dependent on the release of special chemicals. Furthermore, the tissues in the Central Nervous System produce some hormones, as well as the neurotransmitters. What sets neurotransmitter and hormone apart? Neurotransmitters belong to the nervous system, however hormones belong to the endocrine system. Hormones and neurotransmitters are engendered differently; hormones are engendered by endocrine glands while neurotransmitters are engendered by neurons. The transmission of neurotransmitters is across the synaptic cleft, whereas that of hormones is by blood. Hormones are able to regulate their target organs, whereas neurotransmitters are able to stimulate the postsynaptic membranes. The action of neurotransmitters is extremely fast, which could be up to a few milliseconds. In contrast, effect of hormones could be lost for a long period, which could be in the range of few seconds to a few days.

Addiction of cocaine has proven to be a lifetime addiction and there is always a possibility for relapse even after years of curtailment. These drugs have the ability to alter the physical makeup of the brain.

As a coach, I had a player, who was very polite and worked hard in practice. She was very timid around other teammates. She would stop in to talk to me and never had friends that I could see her relate to. Trying to fit in desperately, she was happy to be included in the “social” activities in college. She got pregnant and her boy friend and her were arrested for conspiracy to deliver cocaine and both sentenced to prison. This course states cocaine can cause an initial rush of pleasure that makes you alert, talkative and confident. With prolonged exposure to meth and cocaine, it can destroy up to 50% of dopamine – producing neurons in certain parts of the brain. This can lead to irreversible symptons of Parkinson’s disease. (Cocaine handout) After several letters from her in prison, she thanked me for being a good listener. I know her family closed their eyes thinking it’s not an addiction, but a social activity that they can quit at any time. This course explains how a higher level of dopamine on a regular basis is needed just to keep you feeling normal. Cocaine can make people feel paranoid, angry and hostile even when they are not high. Prolonged use causes sleep deprivation and loss of appetite. A person can become psychotic and experience hallucinations. It increases the risk that the user will experience a heart attack, stroke, or respiratory failure which can result in sudden death. (Foundation for a Drug-Free

Cocaine also known as crack cocaine is a stimulant drug, a stimulant raises one’s heart rate, attention and awareness and breathing. Stimulants were used to treat respiratory issues but is now prescribed for individuals with ADHD. In the 1800’s is when cocaine began to be seen as an addicting substance due it’s mood-altering effects on one’s brain. Cocaine can be inhaled through a pipe, when in powder form it can be snorted, and some individuals inject the drug into their bloodstream through intermuscular or intravenously. Individuals that use cocaine repeatedly use the drug within a short time span between each time used so that the euphoric high stays longer. The effects that cocaine has on the central nervous system is so

Neurotransmitters are chemicals made by neurons and used by them to transmit signals to the other neurons or non-neuronal cells (e.g., skeletal muscle; myocardium, pineal glandular cells) that they innervate. The neurotransmitters produce their effects by being released into synapses when their neuron of origin fires (i.e., becomes depolarized) and then attaching to receptors in the membrane of the post-synaptic cells. This causes changes in the fluxes of particular ions across that membrane, making cells more likely to become depolarized, if the neurotransmitter happens to be excitatory, or less likely if it is inhibitory.

Stroke. Heart attack. Altered cardiac rhythm. These medical emergencies are common during a cocaine overdose. In addition to these immediate health consequences - prolonged cocaine use can alter the function of vital organs - which includes the possibility of permanent brain damage.

However, everything comes at a price, the short-term health effects are: constricted blood vessels, dilated pupils, nausea, raised temperature and blood pressure, faster heartbeat, tremors and muscle twitches, and restlessness. The long-term effects of cocaine depend on how it is taken. If it is snorted effects include: loss of sense of smell, nosebleeds, frequent runny nose, and problems with swallowing. Ingesting orally leads to severe bowel decay from reduced blood flow. If it is injected, the effects include higher risk of contracting HIV, hepatitis C, and other bloodborne diseases. However, those who use non-needle forms of cocaine are still at risk for STDs because cocaine affects one’s judgement so one may lead to unsafe sexual behavior. Long term effects shared by all forms of cocaine include: being malnourished due to cocaine’s appetite suppressing properties, movement disorders such as Parkinson’s, irritability, restlessness, and severe paranoia which can lead to the loss of touch with reality and cause auditory hallucinations. Along with all the previously mentioned effects, if someone becomes dependent on cocaine, withdrawal symptoms include: depression, fatigue, increased appetite, nightmares, insomnia, and slowed cognitive function. I personally know someone who has tried cocaine and here’s what they said on the matter: