New Delhi Metallo-Beta-Lactamase Essays

Hospitals in the United States do not have to report outbreaks to the government. However, according to the documentary the Centers of Disease Control and Prevention estimated that two million Americans are infected with resistance bacteria, which can result in about 23,000 Americans death each year. This is a hidden and silent epidemic with KPC found in hospitals in 44 states in the United States. In addition, there have been 32 confirmed cases this documentary in 14 countries with NDM-1 gene. The documentary should have explored what the U.S., India and other countries do differently or similarly in treating the superbug NDM-1. The US had in recent years signed a deal with GlaxoSmithKline worth $200 million on development and research of drug resistance antibiotics (Hirschler). GlaxoSmithKline is a “global healthcare group, which is engaged in the creation and discovery, development, manufacture and marketing of

Enzymes are types of proteins that work as a substance to help speed up a chemical reaction (Madar & Windelspecht, 104). There are three factors that help enzyme activity increase in speed. The three factors that speed up the activity of enzymes are concentration, an increase in temperature, and a preferred pH environment. Whether or not the reaction continues to move forward is not up to the enzyme, instead the reaction is dependent on a reaction’s free energy. These enzymatic reactions have reactants referred to as substrates. Enzymes do much more than create substrates; enzymes actually work with the substrate in a reaction (Madar &Windelspecht, 106). For reactions in a cell it is

The development of antibiotics was an important advancement in 20th century medicine. Previously deadly infectious diseases are now routinely treated with antibiotics. Moreover, for modern-day medical procedures such as chemotherapy treatment to be successful, antibiotic use is necessary. For these reasons, the prospect of bacteria developing widespread resistance to antibiotics is a major concern as it would render many modern-day medical therapies unviable.

For many years the identification of microorganisms has been important in the world of medicine. It is essential or correct disease diagnosis in patients and for proper treatment. Knowing the correct identity and characteristics of microorganism is crucial when disease outbreaks occur in populations, also knowing how humans can benefit from microorganisms is important; many can be used in making certain foods or antibiotics.

This particular bacterium is not one that inhabits a specific geographical region as it colonizes within the human body. The disease is

faecalis has a low pathogenicity (scilo), it is a virulent, opportunistic pathogen to be reckoned with and is thought of as a super-bug. This is not only due to its ability to resist a variety of antibiotics, but also its ability to travel and employ biofilm formations. It can grow and adapt in many different environments. It can thrive in a wide range of temperatures and has disregard whether salt or oxygen are present, or whether the pH is basic or acidic. Its resilience on inanimate objects makes it a perfect candidate for transmission to occur within the hospital environment from hand to instrument, but it can also be spread via hand-to-hand contact and from food contamination (Public Health Agency of

Enzymes are the very successful machines of natural life. They are in charge of lowering so as to catalyze responses the enactment vitality for these responses. Enzymes are comprised of proteins interpreted from nucleic corrosive coding material, so they have particular duties inside of a life form. Beta-lactamase is a enzyme that separates beta-lactam anti-toxins like penicillin. In this lab, the viability of the beta-lactamase catalyst was tried at diverse temperatures. The beginning speculation of the trial was that enzymatic action would increment as temperature expanded, in spite of the fact that at 60 degrees Celsius the chemical would denature. This was somewhat reflected in the information. The chemical did denature at 60 degrees; in

Different microbes can transmit and produce different types of diseases and infections. Having an unknown bacterium in the body can be a life and death situation. It is very important especially in the healthcare industry that providers are able to differentiate between organisms that are pathogenic and administer the appropriate treatment to their patients. Applying methods that were previously studied in lab, students must be able to isolate an unknown specimen by using laboratory techniques and biochemical tests.

pneumoniae) leaving me with Sa, Se, Ef, P.pyo, and Ml. Following my dichotomous key, the next test I decided to perform was a catalase test in order to determine if the enzyme catalase is produced by the bacteria. The sample of the bacteria I took did bubble, this indicates that the bacteria does produce the catalase enzyme as well as requiring oxygen to respire. Based on the results of the catalase test there were three possible microbes I could have Ml, Sa, and Se. For my next test I decided to use an MSA plate to determine if my unknown microbe could or could not grow in the presence of the mannitol salt, along with testing to see if it would or would not be able to ferment the mannitol salt. After allowing the bacteria to grow, I noted that the plate remained the same pinkish color it originally was however, I did several white colonies growing on the plate. The pink color that remained shows that the organism is unable to ferment the mannitol salt thus the acidic byproduct that turns the medium yellow will not be produced. Therefore the organism cannot be Sa since that

Often the modes of transmission of this organism are through surgical procedures or venous or urethral catheter insertions, which result in the infection of Enterobacter aerogenes. 2 (www.whatarebacteria.com) It is known to

It would be the amount of substrate (penicillin G) that would vary in increasing amounts in each test tube. One test tube will have no substrate with each tube having more substrate than the other until there is a lot of substrate.

In our world we are surrounded by microorganisms, some are harmless, many are beneficial; they are a part of our normal flora on our skin and in our intestines, providing a barrier against microorganisms that may not be so harmless. It is important, however, to distinguish which microorganisms are potentially pathogenic from those that are not, and when someone does get ill to determine what the organism is so appropriate treatment can be determined.

found that both the drug and the bacteria use enzymes as their defense and attack

Diagnosis and treatment; Even diagnosis of the disease causing microbe is taught so as to give right drug and combat infection effectively. The identification of

Because improvements in nutrition and sanitation have been made, many epidemics have ended. As longevity of life increases, chronic diseases have taken the place of infectious disease as the leading cause of death. The different modes of transmission, disease development, and disease spectrum are all important factors to consider when studying the transmission of communicable diseases. It is also important to know about emerging infectious diseases. It is important to be aware of these diseases so that signs of these symptoms can be easily recognizable to provide the best patient care.