Nobel Prize for Cell Signaling Pathways Essay

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In 2013, the Nobel Prize in Physiology or Medicine was awarded to James Rothman, Randy Schekman, and Thomas Sudhof for their pioneering research in cell signaling pathways. Together, they were able to solve many questions that we had about how this precise cell-­‐to-­‐ cell regulation is carried out. With their works, many scientists across the world can apply their discoveries in various ways.

Due to our profound genomic studies, we have been able to sequence many genomes of various organisms. With the
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There are two processes that are involved in the bulk transport of large molecules. After these large particles are packaged in vesicles, if the molecules are to be secreted from the cell, the transport vesicles fuse with the plasma membrane in a process called exocytosis. James Rothman discovered that “this process is done very precisely as specific protein complexes on the transport vesicles and specific proteins on the plasma membrane bind together to cause this fusion” (1).
When the cell takes in particles from the outside, the cell sinks inward to form a vesicle of materials from the outside in the same principle that James Rothman identified.

The plasma membrane plays a key role in cell signaling pathways. Local signaling is when local regulators are secreted from one cell to trigger nearby
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