Nonalcoholic Fatty Liver Disease

As the Directors at Sharp Reese Medical Facility it is important to raise awareness about the importance of the liver to the human body and the many important functions that it performs for the body such as digestion and the filtration of toxins and drugs from

Ideal cardiovascular health consists of seven factors, and very few individuals in the U.S. population actually meet all seven factors. The liver is also a critical organ in that it is essential for metabolic activities, and metabolic complications of the liver related to obesity result in non-alcohol-related fatty liver disease in both child and adult

Triglyceride concentrations in the liver are much higher than the heart and kidney. The differences between triglyceride and glycerol concentrations were triglyceride includes the free glycerol plus the glycerol. Pure glycerol concentrations were not determined because of reagent availability. The triglyceride concentrations were assumed to be proportional to glycerol concentrations. (Figure 2)

The Merck Manual (2013) highlights the serum lipid profile as the most common diagnostic tool to identify hyperlipidaemia. This measures the total cholesterol, triglycerides, HDLs, LDLs and VLDLs. However, the test should be conducted after the illness has been treated because triglycerides, lipoproteins and cholesterol may be lower due to the body being in an inflammatory state. If there are high LDL levels, lipoprotein(a) and C-reactive protein levels can also be measured in the blood. Those with high triglyceride levels may also have LDL particle number or apoprotein B-100 measurements taken.

In the presented case scenario, we have Mr. Gil Martin who is a 55-year-old Hispanic male. He comes in to the clinic today with complaints of weakness, fatigue, and loss of appetite. A student nurse will be precepting your assessment of Mr. Martin and when collecting subjective and objective data it is important to pay close detail to all findings. Ultimately this patient was diagnosis with cirrhosis, which is an abnormal liver condition that leads to irreversible scarring of the liver (National Institute of Health [NIH], 2017), so during assessment we should pay attention to details leading to this diagnosis.

The MD Anderson Liver Tumor biospecimen resource has been invaluable for a large number of studies or clinical development. The sixth and subsequent editions of the American Joint Committee on Cancer (AJCC) staging of hepatocellular cancer, which was developed by an international consortium led by Jean-Nicolas Vauthey, MD, Professor of Surgery at MD Anderson and co-leader on project 2 of the SPORE, was based upon pathologic review of resected specimens in the Liver Tumor Bank (Vauthey JN J Clin Oncol 2002 20:1527-36). In addition, investigators at MD Anderson examined tissues in the Liver Tumor Bank to elucidate the prognostic significance of the ribonucleoprotein Human Antigen R (HuR) showing that patients with high HuR tumor expression had

This set of particular tests were carried out at Manchester Metropolitan University in the Interdisciplinary Laboratory. Prior to the tests that were going to be carried out the client in question was asked to carry out a Pre-Test Medical questionnaire to assess the risks involved and to see if the client would be able to participate in the tests. The tests that were performed on the client were height, weight, haemoglobin, cholesterol, FEV1 and FVC.

There is an established connection with obesity and high lipids. This can result in increased risk of coronary heart disease. In 1995, it was

This case study is about Abdul Chidiac, a 51 year old male, married with 4 children. He had a medical history of hypertension, hypercholesterolaemia and cirrhosis with two admissions in the last six months. He is a smoker and drinks beer, 5-6 bottles per day. As Carithers & McClain (2010) explained the patient’s medical history is another indicator of the risk for cirrhosis; the progression to cirrhosis is adaptable and may take time over weeks or many years. Cirrhosis is a liver disease characterized by permanent scarring of the

Obesity is the next major epidemiologic challenge facing today's doctors, with the annual allocation of healthcare resources for the disease and related comorbidities projected to exceed $150 billion in the United States. The incidence of obesity has risen in the United States over the past 30 years; 60% of adults are currently either obese or overweight. Obesity is associated with a higher incidence of several diseases, including diabetes, cardiovascular disease, and cancer. Consumption of fast food, trans fatty acids (TFAs), and fructose—combined with increasing portion sizes and decreased physical activity—has been implicated as a potential contributing factor in the obesity crisis. The use of body mass index (BMI) alone is of limited utility

Cirrhosis is the 11th leading cause of death by disease in the United States. Almost one half of these are alcohol related. About 25,000 people die from cirrhosis each year.

Additionally, many chronic liver diseases can lead to cirrhosis. For example, nonalcoholic fatty liver disease (NAFLD) can lead to cirrhosis and is associated with obesity, hyperlipidemia, metabolic syndrome and type 2 diabetes mellitus. Hereditary metabolic disorders such as hemochromatosis and Wilson disease can also lead to cirrhosis (McCance & Heuther, 2014). It seems the cause of cirrhosis is multifaceted. Additionally, many diseases can lead to cirrhosis and it is understandable why the etiology of cirrhosis has not been parsed out, especially because the cause can differ from a

Over two-thirds of adults in the United States are considered overweight or obese [1]. Obesity is a significant risk factor for a number of chronic conditions, including cardiovascular disease (CVD), type 2 diabetes, and metabolic syndrome [2], [3], [4]. Metabolic syndrome is a chronic disease characterized by the presence of individual risk factors including: insulin resistance, dyslipidemia (high plasma triglycerides, low high-density lipoprotein (HDL)), hyperglycemia, and hypertension [3, 5, 6]. When evaluating the individual components of metabolic syndrome, dyslipidemia, hypertension, and insulin resistance are also considered risk factors for CVD [3]. High fat mass (FM), especially in the form of visceral fat (VF), is commonly

condition. However, as a good health-care consumer I should have information about that particular test and its alternatives.

Cardiovascular diseases are the number one factor that can erupt from obesity due to the main causes that it brings, like high blood pressure, and LDL cholesterol to a high count while lowering HDL. LDL is the “bad cholesterol”, and HDL is the “good cholesterol”. We need fats in our body for energy or ATP, in our body. If we get more LDL, it can really be a dangerous case, and