Notes On The Fight Against Retroviruses

HIV has affected people all across the world. HIV comes with physical and mental symptoms. The body symptoms include skin flaking off, being dry, skin peeling off (Saliba 23) , fingernails falling off (32), and weight loss (14). Mentally it is hard to sleep, people become weak, and are tired all the time (23). People all across the world are infected with this disease, and the problem with this is the fact that most do not even know they have it. The most people who are infected each year are African Americans, gays, or bisexuals. 10,315 African Americans were infected in 2015. The U.S.A. has estimated about 1.1 million are infected with the disease. Equally to about 12,333 deaths happened in 2014 from AIDS related diseases, and 6,721 deaths from AIDS directly. Although there are a large amount of people getting infected, on the other hand eighteen percent of the population with HIV is declining since 2008-2014 (“U.S. Statistics”). In the world about 33.2 million people worldwide have HIV, with 22.5 million people in sub Saharan Africa are living with this condition, one out of nine people who live in South America have HIV or AIDS (Saliba 8).

According to the Centers for Disease Control and Prevention (CDC), about 50,000 people are infected with HIV each year. In 2010, the most recent year for which this information is available, there were around 47,500 new HIV infections in the United States (p. 1). The population of people with HIV is diverse due to the fact that it does not discriminate. Men and women of any age,

Dr. N.A.S states that one of the antiretrovirals blocks translation of RNA into the proteins required to make new viruses. Some of the current antiretrovirals include reverse transcriptase, fusion and entry, protease, and integrase inhibitors;6,10 however there is not an inhibitor that blocks translation of rna into proteins on the market. Targeting inhibitors specific to HIV has made ARVs increasingly effective and less harmful to humans.

HIV is communicable disease that is caused by virus. This particular virus attacks the immune system which means people who suffer from HIV find it more difficult to fight of infection than the average person who does not suffer from HIV. This disease can be transmitted by direct contact, generally it is transferred by sexual contact between partners in fact 95% of those who suffer from HIV are contracted it this way. It can also be contracted by using dirty needles or any other contaminated tool. It can also be contracted by sharing sexual toys. HIV is commonly found in a person’s bodily fluids this means it is spread through, Sperm, vaginal and even anal fluids, breast milk and blood are also common.

There are many health problems that we face globally and each of them are important for us to be aware of and to take precautions and measures to prevent and treat such diseases that affect our global population. HIV/AIDS is a disease that is spread through direct contact with body fluids from a person who is infected with the virus, these fluids include blood, semen, rectal fluid, vaginal fluids and breast milk. There are an approximate 35 million people living with the disease globally as of 2015 and about 1 million of those people are children under the age of 15 (Aids.gov, 2016). There are approximately 1.2 million people in the U.S. living with the disease and of those individuals many became infected with HIV by needle or syringe sharing,

As have been described above, HIV can have a potential effect on immunological cells, which are important to protect the body from additional infections such as Tuberculosis (TB), Cytomegalovirus (CMV) and other viral or bacterial infections. An effective treatment is needed to reconstruct what HIV has damaged. Antiretroviral therapy (ART) is a common treatment to stop the viral replication and decrease the disease progression, which may lead to a vast decline of the morbidity and mortality. The standard treatment involves a combination of at least three drugs; often known as a highly active antiretroviral therapy (HAART) where the most common types are Nucleoside reverse transcriptase

Human immunodeficiency virus (HIV)/AIDS is a pandemic problem affecting global health. At the end of 2015, 36.7 million people were living with HIV/AIDS globally. The rate of incidence is more prevalent in Sub-Saharan Africa with almost 1 in every 24 adults living with HIV/AIDS. In the united states, HIV/AIDS is a diversified health problem affecting all sexes, ages and races and involving the transmission of multiple risk behavior. However, with the introduction of various prevention programs and antiretroviral drugs, the incidence of HIV/AIDS has reduced.

Trying to find a cure is hard some virus can help but are they to deadly. Scientist are saying that this virus helps but the immune system does not allow it. The Lassa-VSV virus carries a gene that causes it to produce a fluorescent protein that helps researchers track which

HIV is a universal and a pandemic disease has claimed 33 million lives globally in the 1980s. It is approximated that 35 million

HIV and AIDS have affected millions of people throughout the world. Since 1981, there have been 25 million deaths due to AIDS involving men, women, and children. Presently there are 40 million people living with HIV and AIDS around the world and two million die each year from AIDS related illnesses. The Center for Disease Control estimates that one-third of the one million Americans living with HIV are not aware that they have it. The earliest known case of HIV was in 1959. It was discovered in a blood sample from a man in Kinshasa, Democratic Republic of the Congo. Looking further into the genetics of this blood sample researchers suggested that it had originated from a virus going back to the late 1940’s or early 1950’s. In 1999,

Virus may have helped humans in evolution. There are two types of viruses, retrovirus and the virus. The normal type of virus destroys the D.N.A. in cells then reproduces in the cell till the cell explodes. The retrovirus changes the way the D.N.A. thinks. Some scientist believe that was the key to evolution and have evidence to support it. A few scientist look at bacteria that are in extreme condition that are like the beginning of earth conditions. In those conditions they find bacteria and retroviruses. The first retrovirus was found in france 2003 on accident. It was named meme. They also believe by experimenting on sheep they help with birth. Now I wonder would you press a button to get rid of all viruses.

An oncolytic virus (OV) is a virus that preferentially infects and kills cancer cells. OVs posses the ability to selectively infect and replicate in cancer and associated endothelial cells and kill these cells in cancerous tissues while leaving normal tissues unharmed [1]. As the infected cancer cells are destroyed by lysis, they release new infectious virus particles to help destroy other cancer cells or the remaining tumor. The viruses achieve this by a number of mechanisms, including direct lysis, apoptosis, expression of toxic particles, shutdown of protein synthesis, as well as the induction of anti-tumoral immunity.

The most current treatment for HIV is Antiretroviral Therapy (ART). ART is using a combination of HIV medications to treat HIV. If is recommended that everyone with HIV use ART. ART is not meant to cure HIV, but to help people with HIV live longer, healthier lives. There are some complications with the ART that arise. Some drug interactions can occur in the regiments, but the main

Since the beginning of the epidemic, AIDS has killed more than 30 million people worldwide, including more than 500,000 Americans. AIDS has replaced malaria and tuberculosis as the world's deadliest infectious disease among adults and is the fourth leading cause of death worldwide. Over 13 million children have been orphaned by the epidemic. A person who is HIV-infected carries the virus in certain body fluids, including blood, semen, vaginal secretions, and breast milk. The virus can be transmitted only if such HIV-infected fluids enter the bloodstream of another person. This kind of direct entry can occur (1) through the linings of the vagina, rectum, mouth, and the opening at the tip of the penis; (2) through intravenous injection with a syringe; or (3) through a break in the skin, such as a cut or sore. Usually, HIV is transmitted through:

HIV is a virus that is spread almost all over the world. Although in some places health care isn’t as developed and therefore it spreads more in those regions. Sub-Saharan Africa holds more than 70%, 25 million, of all HIV positive people in the world. Second highest is Eastern Europe together with Central Asia with 1.3 million. It is spread over most of the world, including Asia and the Pacific, the Caribbean, Central and South America, North Africa and the Middle East and Western and Central Europe (“The Regional Picture”).