Obesity Is A Significant Risk Factor For A Number Of Adults

3728 Words May 4th, 2015 15 Pages
Over two-thirds of adults in the United States are considered overweight or obese [1]. Obesity is a significant risk factor for a number of chronic conditions, including cardiovascular disease (CVD), type 2 diabetes, and metabolic syndrome [2], [3], [4]. Metabolic syndrome is a chronic disease characterized by the presence of individual risk factors including: insulin resistance, dyslipidemia (high plasma triglycerides, low high-density lipoprotein (HDL)), hyperglycemia, and hypertension [3, 5, 6]. When evaluating the individual components of metabolic syndrome, dyslipidemia, hypertension, and insulin resistance are also considered risk factors for CVD [3]. High fat mass (FM), especially in the form of visceral fat (VF), is commonly associated with many of the risk factors for metabolic syndrome placing obese individuals at an increased risk [3], likely due to the combined effects of dyslipidemia, insulin sensitivity, and chronic low-grade inflammation [7].
While metabolic syndrome is highly associated with obesity [4] and excess adiposity, there is a considerable number of obese individuals who are considered metabolically healthy [4, 8]. Wildman et al. (2008) [9] estimated that 51.3% and 31.7% of overweight and obese individuals were considered metabolically healthy, exhibiting no more than one cardiometabolic risk factor. Unlike obese individuals with disease risks, metabolically healthy obese (MHO) individuals exhibit normal blood lipid profiles (high HDL; low plasma…
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