Oesopharyngeal Pressure

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Advantages and disadvantages of Oesophageal and pharyngeal pressure measurement: Oesophageal pressures are measured using an air or a fluid filled balloon catheter which requires skill, has a steep learning curve and has technical problems which can affect the validity of measurements46. Pedersen et al9 compared oesophageal and pharyngeal pressures in infants on CPAP and found that the pharyngeal pressures were proportional to the set flow rate and had better accuracy. Oesophageal pressures were lower because of an anticipated downstream reduction in pressure as the air flow enters the oesophageal spincter9, 50. Hence, we have used pharyngeal pressure for measuring the CPAP in this study. Study population: 146 oropharyngeal pressure readings from infants receiving BNCPAP for various indications including RDS, TTN, apnea, MAS and post extubation, in the neonatal intensive care unit of Sri Ramachandra Hospital, Chennai. For a flow rate of 6, pressure was set at 4, 5 and 6 and 12 oropharyngeal pressure measurements were obtained respectively during sleep in each group. Similarly for a flow rate of 8, pressure was set at 4, 5 and 6 and 12 oropharyngeal pressure measurements respectively were…show more content…
Exclusion: Infants with airway malformations. Study Period: April 2014 - March 2015 Type of study design: Observational descriptive study Sample size: To observe a pressure difference of ± 2 cm WC for the observed mean oropharyngeal pressure during sleep, we required a sample size of 12 readings in each group for a two sided significance with a power of 80% and a Confidence Interval (CI) of 95%. Sample size was calculated based on the study by De Paoli et al10. Ethics: The study had ethical clearance from the institutional Ethical committee (certification number is CSP- MED/14/FEB/12/64). Informed consents have been taken from the parents in either English or in Tamil (local
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