Opiates Research Papers

Opioid addiction is so prevalent in the healthcare system because of the countless number of hospital patients being treated for chronic pain. While opioid analgesics have beneficial painkilling properties, they also yield detrimental dependence and addiction. There is a legitimate need for the health care system to provide powerful medications because prolonged pain limits activities of daily living, work productivity, quality of life, etc. (Taylor, 2015). Patients need to receive appropriate pain treatment, however, opioids need to be prescribed after careful consideration of the benefits and risks.

Analysis: Opioids are a class of drug that are medically used as very effective painkillers, like fentanyl and morphine, however, they are highly addictive and produce a feeling of euphoria (“Opioids”). This combination leads do a lot of abuse and dependency, where people take more than prescribed in order to feel better. People start off taking the opioid painkillers in order to not feel pain as prescribed by their doctors. Then, they end up getting addicted to them. There are also illicit opioids, such as heroin, that are also highly addictive and also lead to dependency and death (“Opioids”). These illicit versions are taken for recreational reasons, and are also often mixed with other drugs. The combination of taking an unregulated drug in conjunction with other drugs leads to a lot of overdoses.

Opioids are drugs that come from opium. Opium is the dried latex which comes from the opium poppy seed. These drugs create an euphoric effect on the brain. They attach to receptors in the brain to release opium. There are four classes of opioids. Endogenous opioids which the body release on its own at moments of joy. Opium alkaloid, semi-synthetic opioids, and fully-synthetic opioid which are all human made chemically in labs.

Today all across America people are buying and selling prescription drugs and street drugs that are killing our youth and our elders. Opiates directly affect the central nervous system. Narcotics commonly known as "opiates attach to specific proteins called opioid receptors and can be found in the brain, spinal cord and gastrointestinal tract. When

As better and more comprehensive education is provided both to the general public and practicing clinicians the hope is to reduce the negativity surrounding the users of opioids, and to eliminate demeaning language coupled to them as well. This could improve patient morale and help the needless continuation of physical suffering within patients, as they would be more comfortable approaching and using opioids for therapeutic purposes1. That being said there are those within our communities who do abuse these substances and pharmacists must recognize the signs of abusers, it is important for them to reach out, without comment, to help those suffering from opioid abuse once they have been

Methadone is a drug that is primarily used to treat patients who have developed and addiction to opiate agonists such as Heroin, Oxycodone, Morphine and Hydromorph Contin. (Canadian Public Health Association. N/D.) Methadone is also used to treat chronic pain. In treatment patients will undergo a physical exam and blood work to ensure their body can handle the drug. A test is also done on the patient to determine the level of opiate withdrawal the patient is in. Once the patient is determined to require treatment they will be prescribed a dose of Methadone to relieve their withdrawal symptoms as well as reduce cravings. Methadone itself is a synthetic opioid which acts on the same opioid receptors as other agonistic opiates. (Canadian Public

Opiate addiction can cause many negative changes in the brain. This leads to the structure and functioning of the brain to perform lower than usual. As a result of constant consumption of the opiate medications, addicts lose most of their ability to cope with pain naturally without taking use of pain medication (Torres, 2014). This low tolerance of pain leads to the addict experiencing a higher level of pain since they consistently have high levels of opiates in their system (Torres, 2014). Opiates have the ability to produce withdrawal symptoms in a few hours after the last dose (Opiate Withdrawal Timelines, Symptoms and

Opioid abuse is a growing epidemic within the United States. Not only are people abusing the prescription forms of opioids (such as oxycodone - OxyContin, hydrocodone - Vicodin, codeine, and morphine) by taking more than they are supposed to, but they are also being bought, sold, and used on the streets illegally; such as heroin. Opioids are highly addicting because of the high they can induce in a person, causing a dependence and yearning for continued use (NIDA, n.d.) In 2007, the United States was responsible for over 99 percent of the global consumption of hydrocodone and 83 percent of the global consumption of oxycodone (United Nations Publications, 2009).

Today the recent growth of prescription opioid painkillers has made opiate use far more domesticated and widespread than ever before.  Even though heroin use has declined, the use of prescription opiates has increased. The use of prescription opiates for people who are dependent on the drugs for pain reduction has lead to an increase in abuse. When a family member or friend begins taking the drugs, not because they need them, but because they want to feeling, it becomes an addiction. Even though an addict is dependent on opiates, a person who is opiate-dependent is different because of the psychological, physical, and financial effects.

The United States is currently in the grips of an opioid addiction epidemic, in fact, in 2014 drug overdoses became the number one cause of accidental death in the United States, beating out both car accidents and gun violence (Opioid Epidemic, 2016). Of those drug overdoses, 60% involved an opioid. An opioid is defined as natural or synthetic chemicals that bind to receptors in your brain or body (Kirby, 2016). Opioids are typically prescribed to address severe or long term pain. Although they do a lot of good, when misused they can have deleterious effects on the health of an individual and are highly addictive.

This allows an increase in feeling of relaxation and happiness rather than anxiety and depressed. OxyContin addiction not only will incline that chances of neglecting important relationships such as family, wife, husband, boyfriends. girlfriends and friends but it can also cause you to spend money that you cant afford to spend. This will cause the abuser to not only put themselves at risk but also their loved ones. With abusers, being dependent on a drug it can take over their lives, but it can also interfere with nerve and brain function. As the body quickly adapts to the dug that has been chewed, snorted or ingested, it develops a tolerance. This causes the user to need a higher dose for their body to function normally (2). Although the body quickly adapts to the drug, long-term and short-term effects begin to take effect. Short-term effects include the blockage of pain messages from being sent to the brain, this allows the user to stop from feeling any physical pain they may be in. Another short-term effect is it slows down not only the respiratory system but also the central nervous system, allowing the drowsy effect to take place. The positive effects of OxyContin are often the reason why people become addicted to the drug. As for long-term effects it may include the following, increased levels of tolerance, reparatory distress, physical dependence on the drug, and death

Opiates, otherwise known as prescription painkillers, have become an enormous problem in the United States. Addiction, overdoses, and death are only a few of the problems caused by opiates. Painkillers can be prescribed to help lessen chronic pain, pain from surgery, pain from serious accidents, or pain from terminal diseases. Opiates are highly addicting and have become highly abused in the United States in the past few years. Prescription painkillers need to be banned in the United States because of the dangers they bring to the patients to whom they are being prescribed. The FDA needs to become more involved in the awareness of how dangerous these drugs are and place a ban on them.

The short-term effects of opiate use include feelings of euphoria, pain relief, drowsiness, and sedation due to the release of dopamine in the brain. Long-term effects can include nausea and vomiting, stomach cramping, constipation, liver damage, brain damage due to respiratory depression, development of tolerance, and dependency. Other effects from opioid use, while not directly related to the drug itself, include viral hepatitis and HIV due to using unsterile needles to inject the drugs in to the system.

Opiate overdose may cause significant failure to health, physical distress, breathing damage and increase mortality and morbidity. Vitamin D deficiency causes muscle aches, periodontal disease, osteomalacia and osteoporosis [6-10]. Low bone mass has also been reported in opioid-dependent individuals

Narcotics such as morphine also attach to pain receptors to act as endorphins. Essentially, opiate medications put into the body compete with the natural endorphins at the opiate receptor sites. This, however, effects how the body naturally produces endorphins and can in turn lead to withdrawals and addiction. When the body becomes addicted, for example, to morphine, the next dosage will tap into the body’s reward system again and the dopamine levels will be increased. Thus, leading to a lowered production of natural endorphins.