Opioid Pathogenesis

There is no question that the alarming rate of deaths related to opioid overdose needs to be addressed in this county, but the way to solve the problem seems to remain a trial and error approach at this point. A patient is injured, undergoes surgery, experiences normal wear and tear on a hip, knee or back and has to live with that pain for the rest of their life or take a narcotic pain medication in order to improve their quality of life and at least be able to move. The above patients are what narcotic pain medications were created for, a population of people that use narcotic pain medications for fun is what is creating a problem. Narcotics are addictive to both populations, however taking the narcotic for euphoric reasons is not the intention of the prescription that the physician is writing. The healthcare system needs to find a way to continue to provide patients that experience chronic pain with the narcotics that work for them while attempting to ensure the Drug Enforcement Agency (DEA) doesn’t have to worry about a flood of pain pills hitting the streets by granting access to the population with a substance abuse problem.

If you watch the news it should come as no surprise that drug abuse and overdoses have increased dramatically in the United States. According to the National Institute on Drug Abuse, as many as 36 million people abuse opioids throughout the world with 2.1 million in the U.S. who currently suffer from opioid abuse disorders (National Institute on Drug Abuse, 2014). These astonishing numbers are only marginalized when comparing them to opioid related deaths in the United States. With an increase of 137 percent since 2000, deaths from drug overdoses now occur 1.5 times more often than deaths from motor vehicle accidents (Rudd Aleshire, Zibbell & Gladden, 2016). The opioid epidemic in the

    There has been an increase in heroin and opioid abuse in america. It has been affecting everyone and the incoming generation greatly. The use of pain reliever drugs is often the leading cause to abusing opioids and/or heroin. These pain relievers are often addictive and once people are addicted and cut off from them they begin searching for other ways to satisfy their cravings. The prescription drugs are often easily dispensed to people so it’s easier to access. This easy access makes it easier for people to get a prescription, leading to a higher risk of addiction.

According to NIH, millions of people suffer from opioid use disorder throughout the United States. This epidemic has continued to spread and the numbers of people who are becoming addicted is on the rise so much that the total burden of cost is at 78.5 billion dollars per year for prescription opioid misuse, this includes the cost of addiction treatment, criminal justice services, and health care (NIH, 2017. https://www.drugabuse.gov/drugs-abuse/opioids/opioid-crisis) Unfortunately there does not seem to be an end to this epidemic anytime soon. The numbers are unremarkable; natural and semi-synthetic opioids peeked at 14,427, heroin at 15,446 and synthetic opioids other than methadone at 20,145. That is a total of 50,018 deaths for some type

Opioid abuse is a growing epidemic within the United States. Not only are people abusing the prescription forms of opioids (such as oxycodone - OxyContin, hydrocodone - Vicodin, codeine, and morphine) by taking more than they are supposed to, but they are also being bought, sold, and used on the streets illegally; such as heroin. Opioids are highly addicting because of the high they can induce in a person, causing a dependence and yearning for continued use (NIDA, n.d.) In 2007, the United States was responsible for over 99 percent of the global consumption of hydrocodone and 83 percent of the global consumption of oxycodone (United Nations Publications, 2009).

Living with pain is a daily struggle for many among us. We as a society push our bodies past the breaking point and live to tell the tale through opioid pain relievers. What did the many generations before opioids were created do, how was the pain relieved? That’s easy enough to answer they lived with it, or they didn’t. Medical and pharmaceutical interventions have come a long way in the treatment and management of pain, so much so that now we have run into another problem, the epidemic of opioid addiction and abuse. Out of this problem a far greater problem is being seen and that is the health risks associated with any drug used in a recreational form.

Modern day America is plagued by a surplus of tragedy, most may have seen viral videos of these “zombies” slumped in cars or streets and yet it continues. In fact, this terrifying epidemic was created by drugs that were intended for pain relief, Opioids. This includes prescription pain relievers like oxycodone, morphine, methadone, and hydrocodone. Ironically, the well-known street drug, Heroin, is one of the most serious offenders of the Opioid crisis (Anderson). With each day, more mothers, fathers, sisters, and brothers are witnessing and losing loved ones from overdoses, which is why the focus of society absolutely needs to be on a path of action towards the rising deaths, excessive prescriptions and governmental influences in opioid addiction.

The media portrays opioid abuse as a new dilemma, but it actually extends as far back as 1898 when Bayer Co. produced heroin, a drug made from opium, and commercialized it to be a “wonder drug” for those in need of pain relief (Moghe 2016). Today, heroin is known to be a dangerous, illegal, and addictive drug. Before doctors

Dysphoria, formication, anxiety, depression, insomnia and inability to focus on tasks are just some of the many symptoms associated with withdrawing from opiates. Opiates, originally derived from opium plants, have been used medicinally as early as 3400 B.C. Presently, opioids are used to relive pain as they have been shown to aid in decreasing the severity of pain signals moving to the brain. However, long term usage can lead to psychological dependence and neurological changes in the body (Pregolizzi, 2012; Jamison, Butler, Budman, Edwards & Wasan, 2010). As of 2013 opioids were one of the most commonly abused drug in America, second only to marijuana. There have were approximately 1,244,872 emergency department visits related

The misuse and abuse of prescription medications in the United States remains high, but few people are aware of just how big the problem really is. According to ASAM American Society of Addiction Medicine, "Drug overdose is the leading cause of accidental death in the US, with 55,403 lethal drug overdoses in 2015. Opioid addiction is causing this epidemic, with 20,101 overdose deaths related to prescription pain relievers, and also overdose deaths relating to heroin". Opioids are drugs which are prescribed to relieve pain. With continued use, the pain-relieving effects lessen and pain can become worse, so the body can develop dependence on the use of opioid. Opioid dependence causes withdrawal symptoms, which makes it difficult to stop taking

The prescription opioid epidemic affects everyone in society, both directly and indirectly. This epidemic is projected to kill five-hundred thousand citizens within the next decade—almost the whole population of Tucson, Arizona. The opioid epidemic is the leading cause of accidental death. Montgomery County, Ohio, is now the overdose capital of America; meaning that per capita, Montgomery County is the first in the nation for overdose deaths.

Opiate overdose may cause significant failure to health, physical distress, breathing damage and increase mortality and morbidity. Vitamin D deficiency causes muscle aches, periodontal disease, osteomalacia and osteoporosis [6-10]. Low bone mass has also been reported in opioid-dependent individuals

Opiate addiction is an intricate part of the history here in the United States and globally. It is a cycle of abuse, misinformation, medical discovery, pain, and death that spans generations. While many naively believe that this type of addiction is unique to the late 20th and 21st century, it is one that our ancestors battled. Among laymen and physicians, there is a mixture of misunderstanding about what this type of addiction is and how it, not only, stems from the nature of opiates but the psychological factors behind this type of disease. Opioid and Heroin addiction are treatable with a combination of chemical treatment and counseling. Having worked in a Methadone clinic that specialized in this specific combination treatment that required

Many individuals in the United States that abuse opioid drugs have risk factors that have shown an association of risk factors that influenced these behaviors. One being, those whose parents were drug-user or suffered from mental health illnesses, child abuse and maltreatment, and had poor supervision (Substance Abuse and Mental Health Services Administration, 2015). Also, communities with high violence and poverty rates show an increased risk of opioid abuse (Substance Abuse and Mental Health Services Administration, 2015). Lastly, social norms and laws favorable to opioid use, as well as racism, and lack of economic opportunity are also very influential in the abuse of opioids (Substance Abuse and Mental Health Services Administration, 2015).

“Prescribed opioids, Heroin, and Fentanyl have killed more than 42,000 people in 2016, according the Centers for Disease Control and Prevention, 40 percent of the 42,000 deaths were brought on from prescribed opioids.” (“Golgowski”) The epidemic of opioids affects multiple communities everywhere, and the company Purdue Pharma, has seen the effects of the drug they produce. Although there are pros and cons to this drug, the bad outweighs the good. While describing the effect of Oxycodone of the good and the bad, and how it is used.