Ossifying Fibroma Case Study

Osteosarcoma is also called osteogenic sarcoma in medical term (“Osteosarcoma”, n.d.). This cancer usually develops in growing bones. Although it can occur at any age, it‘s most commonly found in teenagers and young adults and is slightly more common in males than females. Any bone in the body can be affected, but the most common sites are the arms or legs, particularly around the knee joint(“Osteosarcoma: An Introduction.”, 2012). This cancer is caused by benign tumors and other bone diseases, radiation exposure, genetic factors, children, adolescents, males more than females.(“Osteosarcoma: An Introduction.”, 2012)

Fibrodysplasia ossificans progressiva also known as FOP is a one of the rarest, most disabling genetic bone conditions known to medicine. FOP causes muscles, tendons, ligaments, and other connective tissues to turn in to bone. Movement becomes limited in the affected areas of the body. People with FOP typically have malformed toes at birth, meaning the big toe is typically shorter than normal and abnormally turned outward in a position called a valgus deviation. Symptoms of FOP start to show up in early childhood. Most people with FOP develop painful tumor-like swellings also known as fibrous nodules. The fibrous nodules are visible on the neck, shoulders, and back.

Fibrodysplasia ossificans progressiva is a rare and incapacitating condition of skeletal malformations and progressive heterotopic ossification. It was originally called myositis ossificans progressive (MOP) and was discovered by a French physician, Guy Patin, who came across a patient who had FOP. He described the patient to have “swellings” in his back (History of FOP, 2009). They changed it from MOP to FOP because other fibrous tissues in addition to muscle are replaced by bone. FOP causes excessive bone growth and begins in the early stages of life.

Fibrodysplasia Ossificans Progressiva disease also known as ‘FOP’ is a rare genetic disease of the connective tissue. FOP can be characterized by malformations of the big toe. This malformation is a characteristic feature that helps distinguish the disease from other muscle and bone issues. It is a disease that is caused by a mutation in the bodies repair mechanism. This causes muscle and connective tissue such as ligaments and tendons, to be ossified spontaneously or when they are damaged. Sometimes the bone can be permanently frozen in place in some cases. FOP is usually seen in early childhood it starts with the neck and shoulder and proceeds down the body and into the limbs. People who suffer from FOP are basically imprisoned by their own skeleton. Majority of FOP cases are sporadic and are a result from a new gene mutation (Lerardi-Curto and Lynne). This mutation is an autosomal dominant disorder; this means it affects those who are heterozygous with a homozygous recessive partner because of this it means their children will have a fifty percent chance of having FOP. Most cases of FOP are a result from new mutations in the gene. People who have FOP and have the heterozygous phenotype have less severe affects than those who have the homozygous dominant phenotype. Patients who have FOB have the ossification gene that is still working in their bodies and it is usually turned off after a

FOP, also known as Fibrodysplasia ossificans progressiva, is a rare genetic condition. Approximately, there are about one in every two million births that get this rare disease. Sadly, a little boy named Josh was one in those 2 million births who received this rare disease. People’s lives are affected with this disease because it causes bone to form from soft tissue and usually by the victims 40s; it confines them to immobility before it takes their life. This is evident because of Dr. Snyderman’s facts, the symptoms of FOP, and how it is affecting him with just doing simple things.

There has been a case of SqCc that has impacted the parietal bone. An 80 year old Australian man was admitted with a rare form of metastatic carcinoma of the lung. After a physical examination, it was conclude that there was an extensive amount of bone destruction. The authors were unable to find a past case with this same problem. It is an unusual disease with very limited resources and background knowledge.

Methods: - A total of 250 radiographs of primary mandibular molars (126 first molars and 124 second molars) of 5- to 12-year-old patients were reviewed, and the patterns of root resorption and the premolar location were evaluated.

Also, these lesions tend to obviate on their own following the extraction or exfoliation of the related tooth and are usually not submitted for histopathological investigation [11]. Histologically, there is no distinction between the cysts associated with primary teeth and those of permanent teeth with the exception of scarcity of cholesterol crystal slits in primary teeth cysts. This is because of the fact that the lesion associated with the primary teeth exist for shorter length of time before removal in contrast with permanent teeth [3]. In the present case the treatment plan comprised extraction of the primary tooth involved followed by enucleation of the cyst. The other conservative and effective alternative treatment option mentioned being marsupialization of lesion with a fixed resin tube placed in alveolar hole after the extraction of the affected primary tooth [12]. In a similar case the treatment included extraction of the affected primary teeth followed by marsupialization. A removable appliance with a resin extension into

Purpose/ Objective : Odontogenic keratocyst (OKC) is a developmental odontogenic cyst, originating from dental lamina remnants. It comprises around 3-11% of the odontogenic cysts. Odontogenic keratocyst is asymptomatic swelling that tends to grow into the anterior and posterior where there is medullary bone in between. The lesion grows slowly with potential for aggressive biologic behaviour and high recurrence rate.

Nasolabial cysts are relatively rare, comprising approximately 0.6% of all jaw cysts. The cysts can be observed at virtually any age, although they are exceedingl uncommon in patients younger than 10 years. Patients in the age range from 30 to 50 years are most frequently affected. Interestingly, there is a strong female gender bias for nasolabial cysts, with female to male incidence ratios ranging from 2.7:1 to 3.7:1. People of East Asian ethnicity also appear to have a higher incidence.2

Adenomatoid odontogenic tumor (AOT) is a benign epithelial odontogenic tumor, characterized by slow and progressive growth. The central lesions, when associated with a non-erupted permanent tooth, are the follicular types. Histological variants of the tumor or combined lesions may hinder the diagnosis, resulting in the inadequate planning of treatment, which may affect the patient´s prognosis. The aim of this study is to report a case of a wide follicular AOT on a less frequent location, with extensive calcifying epithelial odontogenic tumor (CEOT) - like histopathological areas, which was treated by surgical excision as a combined epithelial tumor. Afterward surgery, the teeth displaced by the tumor were repositioned with orthodontic treatment,

Periodontal osseous surgery steps include making an incision on the gingiva to make a path to see the bone and osseous defects. They are made on both the facial/buccal aspect

Monostotic fibrous dysplasia of the jaws occurs with apparently equal predilection for males and females, although some reports show a mild predominance of females. It is more common in children and young adults than in older persons. The mean age of occurrence in the 69 patients reported by Zimmerman (29) and his associates was 27 years, while in 53 patients with craniofacial fibrous dysplasia reported by Gardner and Halpert (30), the mean age was 34 years.

Based on the origins and interactions of the odontogenic tissues in tumor development; odontogenic neoplasms are classified into three subtypes groups and may be characterized as epithelial, mesenchymal, or mixed. These lesions encompass a heterogeneous group that is categorized from hamartomas to benign and rare malignant neoplasms with variable aggressiveness. The molecular pathogenesis of odontogenic tumors remains unclear, assessment of cellular markers is suitable for the better understanding of the biologic behavior of these

Involvement of the mandible often results not only in expansion of the lingual and buccal plates but also bulging of the lower border. Superior displacement of the inferior alveolar canal is not uncommon. Periapical radiographs of the involved dentition often demonstrate narrowing of the periodontal ligament space with an ill-defi ned lamina dura that blends with the abnormal bone