Otsuka's Abilify Mycite Research Paper

Schizophrenia is a disorder that is characterized by a broken thought process and poor emotional responses. Typical symptoms of this disorder include delusions, paranoia, hallucinations, social dysfunctions,

Schizophrenia is a mental disorder often characterized by abnormal social behaviour and failure to recognize what is real. Common symptoms include false beliefs, unclear or confused thinking, auditory hallucinations, reduced social engagement and emotional expression, and inactivity. A person with schizophrenia often hears voices, experiences delusions and hallucinations and may believe thoughts, feelings and actions are controlled or shared by someone else.

Some of the current changes that can be seen in regards to prescription privileges include changes in the ways that physicians and mental health professionals are able to prescribe medications to their patients. According to Brenda Smith of the APA (2012), currently patients receive their medications for psychological conditions by a physician usually without having been evaluated by a mental health practitioner according to the CDC. The trend includes individuals to visit their general health practitioners in order to receive psychotropic medications such as antidepressants and anxiolytics. The problem with individuals receiving these medications from other sources include: deterrence

The proposed Right-to-Try bill requires the federal government to allow for unrestricted access to investigational drugs, biological products, or devices to patients who are considered to have been diagnosed with a life-threatening illness when prescribed by a physician. The proposed law stipulates that the patient must have exhausted all other treatment options, and the investigational drug must have completed a

First off I would like to tell you what exactly schizophrenia is. Schizophrenia is a brain disease, with concrete and specific symptoms due to physical and biochemical changes in the brain. This illness strikes young people in their prime age usually between 16 and 25. Schizophrenia is almost always treatable with medication. Contrary to what most think schizophrenia is not a "split personality", or caused by childhood trauma, bad parenting, or poverty, and not the result of any action or personal failure by the individual.(3)

Americans must wait up to 19 years after a discovered treatment before they can participate in benefits of a new medication (Philipson & Sun, 2008). The regulatory process drug manufacturers need to endure before releasing potentially life-saving medication is an extremely expensive, time-consuming process. The Center for Drug Evaluation and Research (CDER) is the main department of the Food and Drug Administration (FDA) responsible for the safety of drugs (both prescription and over-the-counter) sold in the United States (Food and Drug Administration, 2011). This department scrutinizes the testing of new drugs and

In 1955, antipsychotic medications were introduced to help mental disorders. These medications are usually taken orally in which help relieve symptoms for periods of days. The misuse or abuse of the medications are low. There are three generations of antipsychotic medications. The first generation is known for reducing hallucinations and delusions, but not affecting problems like disorientation or depression. An example would be chlorpromazine, brand name being Thorazine. Some negative side effects of taking the first generation drugs are Parkinson’s-like symptoms, tardive dyskinesia, and weight gain. Next, the second generation drugs minimized the outcome of the individual getting Parkinson’s-like symptoms. An example of this generation would be Clozaril. “A unique feature of Clozaril is the 1 to 2 percent chance of developing a potentially lethal blood disease called agranulocytosis” (Levinthal 282). This disease decreases white blood cells and affects the immune system. If early signs of this disease start to appear the patient will stop taking Clozaril and recover. Lastly, the third generation has shown to be the most effective on schizophrenia. Abilify is an example of this generation drug. It does not have a risk of Parkinson’s, tardive dyskinesia, or diabetes. Abilify blocks specific serotonin receptors in which prevents negative side effects from happening. These different

Physicians must prove that there is no other comparable or satisfactory alternative in order to diagnose, monitor, or treat their patient’s condition or disease. They must also conclude that the potential risk of the product is not greater than the risk of the disease or condition (Expanded Access 1). The FDA must also determine that here have been enough tests done already to provide sufficient evidence as to the safety and effectiveness of the product and its use in the case (Expanded Access 1). In addition, the FDA must also be certain that by providing this product to patients outside of the clinical trial it will not interfere with the clinical trial, and the FDA acceptance of the drug (Expanded Access 1). Another requirement is that the company developing the pharmaceutical product, or the clinical investigator, submits a treatment plan (clinical protocol) for the patient, which must follow the FDA’s regulations for INDs (Investigational New Drug) or IDEs (Investigational Device Exemption Application), which describe the use of the investigational product (Expanded Access 1). Pharmaceutical companies must also submit a draft of the Data Development Plan (Expedited Access Pathway Program).

Schizophrenia is a mental illness that inhibits a person’s ability to think clearly, manage their emotions, make their own decisions, and associate with others. It is a complicated, long term illness that affects one percent of Americans. Even though Schizophrenia can occur at any age, it is more common for men in their early twenties and early twenties to late thirties in women. It is possible to lead a happy, fulfilling life with Schizophrenia. (Nami 2016)

Antipsychotic medications are proven to help in treating acute psychosis and to reduce the risk of future psychotic events. People with severe symptoms require hospitalization to ensure safety, proper nutrition, adequate sleep, and proper hygiene. Some common medication used to treat schizophrenia are, trifluoperazine, flupenthixol, loxapine among others. There is a side effect from every medication we take, and there is no exception for antipsychotic medications. These medications may cause, drowsiness, dizziness, blurred vision, rapid heartbeat, sensitivity to the sun, rashes, and menstrual problems for women. People taking these medications should not operate machinery or drive a car until they adjust to all of their medications. However, people might need to try several medications until they find the appropriate medication for them. People should not stop taking any medication without the proper recommendation from their doctor. Not taking their medication adequately may cause a relapse and the symptoms come back or usually their symptoms get

Schizophrenia is a chronic brain disorder that affects more than one percent of the population. When schizophrenia is active, symptoms can include delusions, hallucinations, trouble with thinking and concentration, and lack of motivation. However, when these symptoms are treated properly, a large portion of those diagnosed will greatly improve over time.

Schizophrenia is a disabling brain disorder that has affected many people over the years. This is not a common disease but it can be a serious and chronic one. Worldwide, about 1 percent of the population is diagnosed with schizophrenia and about 1.2 percent of Americans are diagnosed.

Schizophrenia is a chronic and severe mental disorder that affects how a person thinks, feels, and behaves. Schizophrenia is not as common as other mental illnesses in fact only about 1% of all people worldwide are diagnosed with it. The symptoms of this disorder can be quiet disabling. Signs of schizophrenia usually appear in late adolescence or early adulthood. It is relatively rare for older adults and children to start developing signs of schizophrenia, but it does happen. The symptoms of schizophrenia can be categorized in three groups: positive, negative, and cognitive symptoms. Positive symptoms are psychotic behaviors not typically seen in healthy people. People with positive symptoms tend to lose touch with some aspects of reality. These symptoms include hallucinations, delusions, thought disorders, and movement disorders. The most common symptoms are hallucinations and delusions. Hallucinations are sensory experiences that occur in the absence of a stimulus and they can occur in any of the five senses (visual, hearing, smell, taste and touch). The most common type of hallucination found in people with

In the United States, a drug can only be advertised legally after being approved by the Food and Drug Administration (FDA). Once attaining at least one FDA-approved use, physicians can prescribe a drug for other unapproved uses, based on their clinical judgment; this is referred to as “off-label use” (McCambridge, 2008). In general, marketing drugs for off-label uses is illegal; however, pharmaceutical companies have gone to various lengths within their legal rights to accomplish exactly that.

The DSM- V defines Schizophrenia Spectrum as a severe brain/mental illness, and when it’s present it’s characterized by incoherent or illogical thoughts, behaviors, speech, delusion/ hallucination, such as hearing voices. The symptoms are noticeable typically late in adolescence or early in adulthood. (American Psychiatric Association,2017). Encyclopedia of psychology (8th Volume Set). The hallmark of schizophrenia is called “Psychosis,” and it’s clinical presentation differs from one patient to another. (James N. Butcher, Jill M Hooley, Susan Mineka) Abnormal psychology (6th edition, pg.444). People have schizophrenia worldwide. Schizophrenia as the prevalence rate of approximately 1.1% of the populations that are age 18 or over (NIMH).