Outbreak Of A Rare Species Of E. Coli

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Last summer 2011, Germany stumbled upon an outbreak of a rare species of E. coli O104:H4 (Pennington 2011). The causative strains appeared to have features from two different E. coli pathotypes of enteroaggregative E. coli (EAEC) and shiga-toxin-producing E. coli (STEC) called enterohaemorrhagic E. coli (EHEC) (Bloch, Felczykowska and Nejman-Faleńczyk 2012). The main effect from this strain causes major incident of gastroenteritis and unusual develop of haemolytic-uremic syndrome (HUS) among the affected patients (Rasko et al 2011). HUS often described as group of disease of haemolytic anaemia, acute renal failure and thrombocytopenia (Schifferli eta al 2009). And it is known to be the result of infection by pathogens that produce shiga-toxin (Walker, Applegate and Black 2012). This particular strain possessed several identical characteristics with some older STEC cases but with different serotypes such as E. coli O105:H7, O121:H19 and O111:H8 (Scheutz et. al 2011). At the end of the outbreak, nearly 3500 cases of EHEC were recorded with 850 patients experience the progression to HUS and 82 deaths (RKI 2011).

On 1st May, hospital in Germany received patient with gastroenteritis symptoms and believed to be the first case that linked with the outbreak (Altmann et al 2011). As of the first week of May, which was the presumed initial onset of the disease, HUS cases started to develop and around 0 to 2 new cases of HUS were recorded daily. Then, since 9th May, it started to show

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