Overview Of Opioid Use Disorder

Opioid use in the US has increased over the years, and this has led to an increase in substance abuse. Substance abuse is not only associated with use of illicit drugs but also prescription drugs. In 2015, of the 20.5 million reported cases of substance abuse, 2 million had an abuse disorder related to prescription pain relievers and 591,000 associated with heroin.1 The increase in substance abuse disorder has led to an increase in opioid related death. In 2015 drug overdose was the leading cause of accidental death in the US with 52, 404 lethal drug overdoses.2

Opioid addiction is so prevalent in the healthcare system because of the countless number of hospital patients being treated for chronic pain. While opioid analgesics have beneficial painkilling properties, they also yield detrimental dependence and addiction. There is a legitimate need for the health care system to provide powerful medications because prolonged pain limits activities of daily living, work productivity, quality of life, etc. (Taylor, 2015). Patients need to receive appropriate pain treatment, however, opioids need to be prescribed after careful consideration of the benefits and risks.

The use of opioids and other drugs continues to gradually increase in the United State. According to Centers for Disease Control and Prevention (CDC), the number of overdose deaths involving opioids has quadrupled since 1999” (CDC website). Individuals are abusing prescription opioids such as oxycodone, hydrocodone, and methadone. Prescriptions opioids that are supposed to be used as pain relievers, cough suppressants and for withdrawal symptoms are being use by individuals in order to feel relaxed or for the overwhelming effect of euphoria. These types of drugs are to be taken orally, but people are snorting, smoking, and injecting them in order to get a better high. I have personal encounters with opioid drugs and opioid abuser on a regular

Opioid drugs are some of the most widespread pain medications that we have in this country; indeed, the fact is that opioid analgesic prescriptions have increased by over 300% from 1999 to 2010 (Mitch 989). Consequently, the number of deaths from overdose increased from 4000 to 16,600 a year in the same time frame (Mitch 989). This fact becomes even more frightening when you think about today; the annual number of fatal drug overdoses in the Unites States now surpasses that of motor vehicle deaths (Alexander 1865). Even worse, overdose deaths caused by opioids specifically exceed those attributed to both cocaine and heroin combined (Alexander 1865).

Analysis: Opioids are a class of drug that are medically used as very effective painkillers, like fentanyl and morphine, however, they are highly addictive and produce a feeling of euphoria (“Opioids”). This combination leads do a lot of abuse and dependency, where people take more than prescribed in order to feel better. People start off taking the opioid painkillers in order to not feel pain as prescribed by their doctors. Then, they end up getting addicted to them. There are also illicit opioids, such as heroin, that are also highly addictive and also lead to dependency and death (“Opioids”). These illicit versions are taken for recreational reasons, and are also often mixed with other drugs. The combination of taking an unregulated drug in conjunction with other drugs leads to a lot of overdoses.

According to the Diagnostic and Statistical Manual of Mental Disorders, 5th edition (DSM-5, opioid use disorder (OUD) is characterized by patterns of opioid use that are problematic and persist for at least one year (American Psychiatric Association, 2013). Evidence of problematic use of opioid is demonstrated through the presence of at least 2 symptoms which include withdrawal, craving, and continued use of opioids despite the disruptions it causes in personal and professional life. The substances used by persons with OUD are heroin and nonmedical pain relievers ([NMPR]; i.e. nonmedical use of opioid pain relievers), and estimates for DSM-5-defined OUD tend to combine the prevalence of use for each of these substances to determine overall

The United States currently faces an unprecedented epidemic of opioid addiction. This includes painkillers, heroin, and other drugs made from the same base chemical. In the couple of years, approximately one out of twenty Americans reported misuse or abuse of prescriptions painkillers. Heroin abuse and overdoses are on the rise and are the leading cause of injury deaths, surpassing car accidents and gun shots. The current problem differs from the opioid addiction outbreaks of the past in that it is also predominant in the middle and affluent classes. Ultimately, anyone can be fighting a battle with addiction and it is important for family members and loved ones to know the signs. The cause for this epidemic is that the current spike of opioid abuse can be traced to two decades of increased prescription rates for painkillers by well-meaning physicians.

America has a major problem with opioid addicts, and many facilities are helping the addicts by providing safer options to taking the drugs their bodies crave. Methadone clinics are places where people addicted to opioids can receive medicine-based therapy. Opioid use, drugs such as heroin, morphine, and prescribed painkillers, has increased in the US with all age groups and incomes. People become addicted to these drugs when they are prescribed, recreationally used with other addicts, or they are born addicted. Many health institutions are addressing this issue with an estimated 2.1 million people in the United States suffering from substance use disorders related to prescription opioid pain relievers in 2012 and an estimated 467,000 addicted

Although the collection of findings from several types of genetically informative research designs does provide compelling evidence for the influence of genetics and heritability on the risk for addiction, they do

Considerable cautions have been obtained throughout the United States to decrease the misuse of prescription opioids and helps to minimize opioid overdoses and related complications. Even though the pain medications have a significant part in the treatment of acute and chronic pain situations, it sometimes happen that the high dose prescription or the prescribed medications, without having enough monitoring, can create bad outcomes. It is always a dilemma for the providers to find who is really in need of pain medications and to identify those who are questionably misusing opioids.

Correspondingly, pharmaceutical opioids are not the only narcotics consumers can get their hands on. It is said that heroin, an illegal but natural opiate, “... scheduled 1 controlled substance in the United States…” (AmericanAddictionCenters) Taking heroin puts consumers at a high risk for addiction and abuse. Although heroin is a very dangerous drug it does dull pain, impair cognition and the senses, increase sedation, and slow functions of central nervous system. It is stated that “... heroin is the fastest-acting opiate.” (AmericanAddictionCenters). Heroin is described as a brown, or white powder or sticky substance that may be snorted, smoked, or injected, giving consumers a sense of “rush” or “high” that comes very rapid and very intense. Due to the fact that prescription opioids are becoming more expensive and less accessible many people turn to heroin, a much cheaper opiate. Not to mention, but three out four consumers who first started off by taking prescription medication who then became abusive of them now look towards the “high” of heroin. It's no coincidence that opioids, illegal or not can cause severe damage to the consumer that may even lead to deaths due to overdose. Above all, “heroin and other opioid drugs interact with the dopamine levels in the brain,which is what causes the burst of pleasure associated with their use.” (AmericanAddictionCenters) Clearly the abuse of any drug leads to drug tolerance, dependence, and last but foremost addiction.

Opioids are painkillers, such as—morphine, methadone, Buprenorphine, hydrocodone, and oxycodone ("What drugs are opioids?"). The opioid crisis is a national crisis that has caused 250,000 fatalities from 2000 to 2014. This crisis is a torrent of painkillers, black-market synthetic versions and heroin. A report from a federal Substance Abuse and Mental Health Services Administration shows more adults use prescription painkillers than cigarettes. Many experts have compared this crisis to the IIIV and AIDS epidemics because it has caused citizens to be cautious. Opioids have been a major discussions topic, which has caused many officials to brain-storm ways to prevent further complications.

As we all have researched and found out the devastating numbers to the opioid epidemic “the abuse of prescription and non-prescription opioids is one of the greatest threats facing public health in the United States today. It is estimated that as many as 2.5 million people in the US are suffering from opioid addiction related to prescriptions, and an additional 467,000 are addicted to heroin”(2017).

According to NIH, millions of people suffer from opioid use disorder throughout the United States. This epidemic has continued to spread and the numbers of people who are becoming addicted is on the rise so much that the total burden of cost is at 78.5 billion dollars per year for prescription opioid misuse, this includes the cost of addiction treatment, criminal justice services, and health care (NIH, 2017. https://www.drugabuse.gov/drugs-abuse/opioids/opioid-crisis) Unfortunately there does not seem to be an end to this epidemic anytime soon. The numbers are unremarkable; natural and semi-synthetic opioids peeked at 14,427, heroin at 15,446 and synthetic opioids other than methadone at 20,145. That is a total of 50,018 deaths for some type

Although opiates can relieve pain and improve quality of life temporarily, the opioid epidemic is becoming a widespread problem all over the United States. Opioids are drugs acting on the nervous system to relieve, but continued use can lead to physical dependence and withdrawal systems leading to opioid abuse. This includes codeine, morphine, oxycodone, fentanyl used daily by healthcare professionals. We need to realize that this is a more difficult problem to address if no one understands how it affects individuals. Why is this important?