preview

PET/CT Scan Paper

Decent Essays

Interpretation of PET/CT scan
There are different methods for assessment of radiotracer uptake by normal and pathologic tissues, such as visual inspection, the standardized uptake value (SUV) and the glucose metabolic rate. Visual inspection in analysis of PET-CT results is used by comparing PET and CT data, as well as viewing fused PET-CT images. SUVs are used for semi-quantification of FDG uptake. Another method of quantification of dynamic PET results is the more complex glucose metabolic rate calculation (Kapoor et al, 2004).
Standardized Uptake Value
The SUV is a semi-quantitative assessment of the radiotracer uptake from a static (single point in time) PET image. The SUV of a given tissue is calculated with the following formula: SUV= tracer activity …show more content…

In addition to its physiologic accumulation in different organs, it can accumulate in non-neoplastic pathologic conditions, including infection, whether acute or chronic infection such as tuberculosis, granulomatous diseases such as sarcoidosis , and autoimmune disease such as Grave’s disease. In addition, the 18F-FDG uptake can be enhanced by inflammatory induced changes, which include post-operative healing scars and post-radiation therapy. A unique example of an inflammatory condition is the one caused by the atherosclerotic plaque formation that is associated with an abundance of macrophages known by its avidity to 18F-FDG. The degree of uptake is usually less than the uptake within the neoplastic tissues. However, there is clearly an overlap between the 2 conditions and, in some cases; the uptake could even exceed the neoplastic uptake. Furthermore; the image interpreter should be aware of a high accumulation of 18F-FDG in some benign tumors, such as giant cell tumor, fibrous dysplasia of the bone, and adenomatous polyps in the colon. Occasionally one will also see breast-related activity. Breast activity will be more obvious in lactating females (Abouzeid et al,

Get Access