Pancreatic Cancer Research Paper

According to Professor John Neoptolemos, "There are approximately 7,000 new cases each year - but it is one of the most lethal cancers." The main reason for the low survival rate from pancreatic cancer is due to its difficulty in finding this cancer early. By the time a person has symptoms, the cancer has often reached a large size and spread to other organs. Because the pancreas is deep inside the body, the doctor cannot see or feel tumors during a routine physical exam. There are currently no blood tests or other tests that can easily find this cancer early in people without symptoms. Tests for certain genes in people with a family history of the disease can help tell if they are at higher risk for cancer. There are some new tests for finding pancreatic cancer early in people with a strong family history of the disease, but these tests are complicated and expensive. Some symptoms of pancreatic cancer include jaundice, a yellow color of the eyes and skin caused by a substance buildup in the liver, pain in the belly area or in the middle of the back, significant weight loss over a number of months, loss of appetite, digestive problems including nausea, vomiting, pain that tends to be worse after eating, a swollen gallbladder that is enlarged, blood clots that form in the veins or cause problems with fatty tissue under the skin, and diabetes. If the doctor has any reason to suspect pancreatic cancer, certain tests will be done to see if the disease is really

Pancreatic cancer is currently number four in cancer related deaths for both male and female. Why is pancreatic cancer awareness not reconsidered like breast cancer (second most common deaths in women.) Pancreatic cancer kills just about or more than breast cancer.

There are not many defined risk factors known for pancreatic cancer. Some risk factors are “family history of the disease, smoking, age, and diabetes (Mayoclinic).” Ideally, pancreatic cancer cells can be detected early and the patient can be treated surgically, but once the cancer has spread, it is usually incurable. A popular clinical tool used to detect pancreatic cancer “is a tumor marker called sialylated Lewis blood group antigen CA19–9, which can act as a sensitive tumor marker, value diminishes when used to detect small, resectable tumors (Maitra,

Pancreatic cancer is the cancer of the pancreas. The pancreas is an organ between the spine and the stomach, and is about 6 inches long. The pancreas is also made up of two major components named the exocrine and the endocrine. A person has to have a pancreas to survive and this cancer can cause a rapid decline in health and eventually death. To prevent this cancer, a person needs to stop smoking, maintain a healthy weight, and check up with your sugar.

Pancreatic cancer is lethal malignancy with a mortality rate that almost equals its incidence. It is the 4th leading cause of cancer-related deaths in the United States, with only a 5-year survival rate of about 6%. Pancreatic cancer remains to be one of the most aggressive tumors. When diagnosed 60-80% patients already have locally advanced or the tumor has already metastasized. A majority of pancreatic cancers are derived from the exocrine part of the pancreas. The exocrine part of the pancreas produces digestive enzymes that help break down proteins, fats, and starches. There are several mutations that have been identified in pancreatic cancer; these mutations can lead to potential biomarkers, leading towards a better prognosis for high risk patients.

The signs and symptoms of pancreatic cancer are always a good thing to detect early so the cancer can be stopped in time and the person does not have to suffer. There are two different types of pancreatic cancer with different symptoms for each. Exocrine pancreatic cancer is one of the most common type of pancreatic cancers that exist today. Although some people might have symptoms of this cancer does not mean that they are diagnosed with this until they are seen by a Doctor and are medically diagnosed. Jaundice is one common symptom of pancreatic cancer and it is distinguished by the yellowing of eyes and skin in a person. Jaundice is caused by the buildup of bilirubin which is a dark yellow-brown substance made in the liver. The liver makes

In 1970, Gey learns that he has pancreatic cancer, and decides to volunteer as a subject in medical research and him under experimental chemo treatments that nearly killed him. Although Gey had the guts to do that I personally would not volunteer to serve as a subject in medical research, as Gey did because those treatments could have killed me like they nearly did to him. But before he died, he informed Mary that it was okay to release Henrietta's real name. It was later informed by Howard Jones that Henrietta's tumor was invasive and not an epidemic carcinoma, he realized that her cancer was "misinterpreted" and "mislabeled" (Skloot 172). Adenocarcinoma arises from glandular cells within the tissue, whereas squamous cell arises from the epithelial

The pancreas is an organ mainly involved in process as digestions and the synthesis of hormones, and as all the others tissues in our body, it can develop cancer. Actually, pancreatic cancer is one of the deadliest types of cancer, either because of the symptoms that only appears at a late stage of the disease, the hard diagnosis and the high chances of metastasis.The symptoms associated with the pancreatic cancer are not specific, such lack of appetite, abdominal ache and weight loss. The diagnosis of pancreatic cancer is hard because the pancreas is located in not favorable position for exams to scan and detect its presence. Pancreatic cancer can also metastasize to other tissues, but mainly to liver tissues and it actually happens before

The client was a healthy individual growing up as a child and that continued throughout his life until about three years ago. He was diagnosed with Hypertension around his fifties, which was controlled with medication. When he became sick and received cancer treatments the hypertension disappeared to where he now has low blood pressure. He has not taken hypertension medication for about three years now. Along with Hypertension, he has been dealing with Basal Cell on the face, chest and back that are assessed frequently. Recently, in August, he had Basal Cell removed from the face and chest and now has a spot on his back that needs to be surgically removed.

The morning light shone up across Mariah’s face which was like a alarm clock for her but a nice,gentle,quiet alarm clock. Mariah only though it would be a normal morning but she started getting a queasy feeling in her stomach and started to feel very nausea.She tried to push it off as last night's dinner but as she thought about it she knew that she was sick.She quickly ran to the bathroom and everything came up. Mariahs mother Robyn quickly ran to Mariahs bathroom and immediately called Urgent Care but they did not open yet because of how early in the morning it was. The ER was their last option; Mariah very much disliked the ER. Although she disliked the ER they knew they had to go so Mariah was done with using the bathroom they hurried

Insulinomas are the most frequent of the pancreatic neuroendocrine tumours accounting for 50% of cases. 10-15% are malignant and more than 99% are found in the pancreas. They are typically small, less than 2cm in size.

Pancreatic cancer has 4 stages, and depending on which one is diagnosed to an individual there are different treatments and different amounts of chemo and radiation. There are also different treatments for each stage. The Whipple procedure can be used in all stages, but is one of the main treatment options for stage one. The other option for the first stage is a total pancreatectonomy with or without postoperative chemotherapy and radiation (Pancreatic Cancer, p.24). For stages two, three, and four, “treatment options include resection (if feasible), radiation with or without chemotherapy, and palliative biliary

Pancreatitis is a severe inflammation of the pancreas. This inflammation occurs due to the pancreatic duct getting blocked by over secretion of pancreatic enzymes. This can occur due to alcohol abuse, gallstones drugs, trauma, infection or an autoimmune disease (Pellico, 2017, p. 715). Pancreatitis can be divided into two categories know as acute and chronic. Acute pancreatitis develops quickly and can become a medical emergency if it is not treated due to the risk of infection, hypovolemia and electrolyte disturbances (Pellico, 2017, p. 715).Acute pancreatitis occurs due to the digestion of pancreatic enzymes in the pancreas. It is accompanied by edema, tenderness, radiating back pain, inflammation and sometimes a fever.

INTRODUCTION Pancreatic cancer is the fourth leading cause of cancer death Worldwide. It is the eighth most common cause of death from cancer in both individuals. Higher incidence is noted as thirteen because of the very poor prognosis. Less than 5% of all patients are still alive only for 5 years after initial diagnosis. It is rarely detected in the early stages and conventional cancer treatment failed due to high resistance to chemotherapy.

They found that when the cut-off value of CTCs was set at 3, the 1-year survival was discrepant between these two groups.The CTC < 3 group displayed significantly increased 1-year survival than CTC 3 group analyzed by log-rank test.The difference in triploid and tetraploid CTCs was statistically significant between the two groups, but there was no significant difference in multiploid CTC between these two groups.Patients with triploid CTCs < 3 had an increased one-year survival compared with patients with triploid CTCs 3.The triploid CTCs < 3 group also had higher overall survival than the triploid CTC 3 group, with a median of 13 months versus 6.03 months which suggests that triploid CTCs may predict the prognosis of pancreatic cancer patients.The differences in tetraploid or multiploid CTCs were not related to patients' overall survival.Among the 40 PC patients, we dynamically monitored 12 metastatic pancreatic ductal adenocarcinoma patients.