Pancreatic Ductal Adenocarcinoma ( Pdac ) Is Highly Malignant With The Lowest Survival Of Any Human Cancer

Pancreatic Cancer is the leading cause of cancer deaths in the United States. Currently there is no cure for this cancer and all available treatments simply prolong the life of the patient. Diagnosing pancreatic cancer rarely occurs at the onset of the disease due to the location of the pancreas in the body. Symptoms such as weight loss and upper abdominal pain do not show up until it is too late. Enzymes produced by tumors known as tumor markers are not reliable until the disease has well progressed. Once you have been diagnosed with Pancreatic Cancer there are different types of treatments that are offered to prolong your life.

Pancreatic cancer is one of the deadliest types of cancer. The cancer is normally not found till it's in the further stages. Pancreatic cancer is when tumors are formed in the pancreas. There are two types of Pancreatic cancer,endocrine and endocrine tumors.Exocrine is the most common type of pancreatic cancer. The main type of Exocrine tumor is Pancreatic adenocarcinoma. About 95% of exocrine tumors are pancreatic adenocarcinoma. This type of cancer usually begins in the ducts of the pancreas. Endocrine tumors and uncommon and make up less than 4% of pancreatic cancer. They both occur in people over 40, and a little more common in men. Pancreatic cancer cause is still unknown, research shows that damage to the DNA can be a cause. It is also

CA 19-9 is a type of tumor marker for pancreatic cancer. It mostly used to help in differentiating between pancreatic cancer and other conditions which include pancreatitis, monitor, to monitor patient’s response to the treatment of pancreatic cancer or cancer progression and to watch for the recurrence of pancreatic cancer (Hui et al., 2015).

I am a lucky yet unlucky man. They call it PanCan, short for Pancreatic Cancer, there are many stages I must say yet there are relatively 20% survival rate and to get to live up to five years? 6% chance. The larger my tumor gets the less likely it’ll be cured. They give me 2 years top, if I am lucky; but I’ve learned to cope with the cancer. You see even people who have 3-5 cm appear to have been cured by surgery, I have hope. On a daily basis I find myself struggling with daily activities, changes in appearances and even anxiety of the future, and on top of all that, I am constantly anxious about treatment and if it will work. Pancreatic Cancer is cruel and ruthless, it will devour one’s

Pancreatic cancer is the cancer of the pancreas. The pancreas is an organ between the spine and the stomach, and is about 6 inches long. The pancreas is also made up of two major components named the exocrine and the endocrine. A person has to have a pancreas to survive and this cancer can cause a rapid decline in health and eventually death. To prevent this cancer, a person needs to stop smoking, maintain a healthy weight, and check up with your sugar.

There are two kinds of pancreatic cancer. There is the endocrine tumors and the exocrine tumors. Endocrine tumors are less common and they affect the islet cells of the pancreas. They tend to be benign and not often become malignant. However the exocrine tumors are much more common and this is what Gene is diagnosed with. Exocrine tumors are often called adenocarcinomas and that means cancer affect the gland cells such as the ducts of the glands (American Cancer Society). Pancreatic adenocarcinomas keep the glands from secreting normal The signs and symptoms of pancreatic adenocarcinoma is darkening of the urine, irritated skin, jaundice, pain in the upper abdomen and back, unexplained weight loss, stomach bloating, weakness, and nausea.

Pancreatic cancer is lethal malignancy with a mortality rate that almost equals its incidence. It is the 4th leading cause of cancer-related deaths in the United States, with only a 5-year survival rate of about 6%. Pancreatic cancer remains to be one of the most aggressive tumors. When diagnosed 60-80% patients already have locally advanced or the tumor has already metastasized. A majority of pancreatic cancers are derived from the exocrine part of the pancreas. The exocrine part of the pancreas produces digestive enzymes that help break down proteins, fats, and starches. There are several mutations that have been identified in pancreatic cancer; these mutations can lead to potential biomarkers, leading towards a better prognosis for high risk patients.

The risk of developing pancreatic cancer is lower among non-smokers, and people who maintain a healthy weight and limit their consumption of red or processed meat. A smoker's chance of developing the disease decreases if they stop smoking, and almost returns to that of the rest of the population after 20 years. Pancreatic cancer can be treated with surgery, radiotherapy, chemotherapy, palliative care, or a combination of these. Treatment options are partly based on the cancer stage. Surgery is the only treatment that can cure the disease; it may also be done to try to improve quality of life without the potential for cure. Pain management and medications to improve digestion are sometimes needed. Early palliative care is recommended even for those receiving treatment that aims for a cure.

Not much is known to help prevent this cancer from attacking your cells not only that but what makes the Pancreatic Cancer so deadly is that not only can this cancer start to develop quickly but can multiply and attack your cells without being detected.The Pancreatic Cancer can only be detected once the cancerous cells are too advance meaning it’s later symptoms start to form such as not only a lost of an appetite but also an unusual decrease in weight due to the cancerous cells that not only affect the pancreas itself but other organs as well it can create tumors. This cancer is rarely found in teenagers they are mostly found in adults from ages around 45 and so on. The pancreas is an organ and or a gland that can be found in the near back of the stomach. The pancreas role to our body is to help create specific hormones that help manage blood sugars and even digestive juice. There are many forms and also many times of pancreatic cancers that were found.

Pancreatic Cancer is a form of cancer in which malignant cancer cells invade the pancreas, a gland that produces digestive fluid and hormones that regulate blood sugar. There are two types of pancreatic cancer: exocrine and endocrine cancer. The malignant cells can infiltrate either the exocrine pancreatic cells, responsible for digestive fluid, or the endocrine pancreatic cells, responsible for regulatory hormones. If the pancreas’ exocrine cells are affected metabolic functions are slowed or stopped completely. Thus, this results in death. If the endocrine cells of the pancreas are affected hormones such as Insulin are unable to be produced and the bodies organs will shut down. Pancreatic Cancer usually begins in the exocrine cells and moves into the endocrine cells (Movva). Pancreatic cancer occurs when cells are mutated from genetic dispositions or detrimental behavioral habits. These mutated cells metastasize to form a tumor. Pancreatic cancer can afflict anyone, However, it is more common in those of African American descent, those with excessive body weights, and those who partake in risky behavioral habits. Pancreatic cancer is an incredibly lethal disease.

On the night my friend died of pancreatic cancer, I lay awake, staring into the darkness, my brain taking me places I didn’t want to go. I got up, made a cup of herbal tea, settled on the couch, and, against my better judgment, logged onto Facebook. I began to scroll through the messages filling her page, mostly from friends and extended family who share her Christian

The first discovery of pancreatic cancer was thought to be during the 18th century, but the first cases were reported in the 1800s. As more cancers were discovered throughout the body, more research was done on it. It has been a problem for hundreds of years, but there was and still isn’t a real cure. Within the last 10 years more light has been shed upon the subject and more research is being done. Pancreatic cancer, like all other cancers has no “cure”, but there are ways to treat it. This type of cancer is one of the most deadly kinds, especially if it is not caught early on. According to Pancreatic Cancer Action, the risks of people ages 45-84 is about 84.6% and when people get diagnosed they are usually under the age of 65 (“Causes

The summer of July 2014 my family got devastating news that my grandfather was diagnosed with pancreatic cancer. Prior diagnose of pancreatic cancer his weight had dropped drastically, couldn’t keep any of his food down, and pigmentation had changed. When he came into the hospital his intestines were wrapped around his kidneys and they found a tumor in his pancreas. By August 2, 2014 my grandfather had lost the battle of pancreatic cancer. His death was slow and painful surrounded by nothing but family and friends. (3)

Cancer is a topic that has been discussed thoroughly due to the burden that it has on the affected. It has also been researched early on. According to Dr. George Demetri, director at the Dana-Farber Cancer Institute, cancer violently spreads and attacks organs in the body, which leads to health complications (PBS 1). The world’s understanding of cancer has evolved, but there are still questions that no one has the answer to. Aktipis notes that cancer cells are able to spread to other organs and withstand treatment (Aktipis 2). In other words,the effectiveness of treatment can not be guaranteed due to the the fast pace of spreading. The study of oncology, another term for cancer, started in the eighteenth century and has grown

Pancreatic cancer has been studied many times. Pancreatic Ductal Adenocarcinoma(PDAC) is a pancreatic cancer and it is the third most leading cause of death by cancer in the world. Many studies and experiments have been done to improve the poor long-time survival rate of this disease. These studies show that a mutation in KRAS show up in many cases of pancreatic cancer. KRAS is what regulates proliferation, differentiation, metabolism, and survival. Being that KRAS has been confirmed in studies of animals that it is an initiation in cancer cells, it is a great therapeutic target. But these attempts to create something to affect the initiation of pancreatic cancer have been hindered in many ways. Scientists have been looking into how greatly