Papilary Thyroid Cancer

ATC likely arises from the loss of differentiation of other thyroid carcinomas, including papillary and follicular thyroid carcinomas. Mutations of the proto-oncogenes,

The thyroid is a small gland that rests in the lower neck. It is in charge of controlling the body’s metabolism by producing hormones (such as T3 and T4) that tell the body’s cells how much energy to use (2). The pituitary gland is in charge of monitoring the quantity of thyroid hormones in the bloodstream (2).

The symptoms are initially asymptomatic they begin to appear such as swelling in the neck, swelling in the lymph nodes and pain, hoarseness and difficulty to breath. The causes are exposure to high levels of radiation, inherited genetic syndromes. There are four types of thyroid cancer: papillary, medullary thyroid cancer, anaplastic thyroid cancer, thyroid lymphoma. According to cancercenters Papillary carcinoma is the most common type of thyroid cancer, accounting for approximately 80% of cases. Papillary carcinomas are slow growing, differentiated cancers that develop from follicular cells and can develop in one or both lobes of the thyroid gland. This type of cancer may spread to nearby lymph nodes in the neck, but it is generally treatable with a good prognosis (outlook for survival). Follicular carcinoma is the second most common type of thyroid cancer, and accounts for approximately one out of 10 cases. It is found more frequently in countries with an inadequate dietary intake of iodine. Follicular carcinoma is also a differentiated form of thyroid cancer. In most cases, it is associated with a good prognosis, although it is somewhat more aggressive than papillary cancer. Follicular carcinomas do not usually spread to nearby lymph nodes, but they are more likely than papillary cancers to spread to other organs, like the lungs or the bones. Hurtle cell carcinoma, also known as oxyphil cell carcinoma, is a subtype of follicular carcinoma, and accounts for approximately 3 percent of all thyroid cancers. Medullary thyroid carcinoma develops from C cells in the thyroid gland, and is more aggressive and less differentiated than papillary or follicular cancers. Approximately 4 percent of all thyroid cancers will be of the medullary subtype. These cancers are more likely to spread to lymph nodes and other organs, compared with the more differentiated thyroid cancers. They also frequently

Medullary Thyroid cancer is the third most common type to get. This cancer is not associated with radiation exposure. This type of cancer is known to spread to distant organs such as the liver, bone, and brain. This type of thyroid cancer is most common in females rather than

The thyroid gland is the gland that makes and stores hormones that help regulate the heart rate, blood pressure, body temperature, and metabolism. Thyroid hormones are essential for the function of every cell in the body. They help regulate growth and the rate of chemical reactions in the body. Thyroid hormones also help children grow and develop. The thyroid gland is located in the lower part of the neck, below the Adam's apple, wrapped around the trachea. It has the shape of a butterfly with two lobes attached to one another by a middle part called the isthmus. The thyroid uses iodine, a mineral found in some foods and in iodized salt, to make its hormones. The two most important thyroid hormones are thyroxine (T4) and triiodothyronine

What is thyroid cancer, and is it dangerous? To answer this one must first know the function of the thyroid. A thyroid is a gland at the front of the neck right under the sound box, which secretes hormones that affect heart rate, body temperature and weight. It also makes calcitonin, which keeps a healthy level of calcium in the body. Thyroids are made up of tissue, when the cells that make up the tissue of the thyroid gland start to form unnecessarily, and cells that are damaged are not killed, tumors called nodules form on the thyroid thus resulting in cancer. Around 45,000 women and 15,000 men were diagnosed with thyroid cancer in 2013 alone, most of whom were above the age of 45. However getting thyroid cancer is not the worst thing in the world as it is treatable but there should still be more investment and research put into this disease so that less risky methods of taking out the cancer can be found.

The thyroid gland is the gland that makes and stores hormones that help regulate the heart rate, blood pressure, body temperature, and metabolism. Thyroid hormones are essential for the function of every cell in the body. They help regulate growth and the rate of chemical reactions in the body. Thyroid hormones also help children grow and develop. The thyroid gland is located in the lower part of the neck, below the Adam's apple, wrapped around the trachea. It has the shape of a butterfly with two lobes attached to one another by a middle part called the isthmus. The thyroid uses iodine, a mineral found in some foods and in iodized salt, to make its hormones. The two most important thyroid hormones are thyroxine (T4) and triiodothyronine

If you have surgery, all or part of your thyroid gland may need to be removed as well.

Most thyroid tumors can be readily diagnosed using histopathologic criteria, which allow the pathologist to differentiate benign from malignant lesions and guarantee an accurate classification for the majority of the variants of carcinomas derived from follicular epithelial cells. However, in most cases, the pathologist is confronted with thyroid lesions in which the distinction between benign and malignant can be quite subtle. The decision favoring one or another has clinical consequences and implies different modalities of treatment. For this reason, the approach to these challenging tumors should include ancillary techniques, immunohistochemistry and molecular profiling, that can improve the standard morphologic assessment (3).

The thyroid gland is found in the front of the neck and produces two main hormones. The hormones are called thuroxine (T4) and Triiodothyronine (T3). Together these hormones regulate the body’s metabolism by increasing energy use in cells, regulate growth and development, help to maintain body temperature and aid in oxygen consumption. These two hormones are regulated by hormones produced by the hypothalamus and pituitary gland. The hypothalamus senses changes in body’s metabolic rate and releases a hormone known as thyropin-releasing hormone (TRH). This hormone then flows through connecting vessels to the pituitary gland which signals it to release another hormone. This hormone is known as thyroid-stimulating hormone (TSH). TSH then makes

The thyroid gland is in the middle of the neck and lays over the trachea. It is a very vascular endocrine gland responsible for secreting hormones such as thyroxine (T4) and triiodothyronine (T3) (Jarvis, 2015). These hormones stimulate the rate of cellular metabolism (Jarvis, 2015). This gland has two lobes. Both lay posteriorly between the sternomastoid muscle and the trachea (Jarvis, 2015).

Medullary thyroid cancer is an indolent neuroendocrine tumor that frequently presents with disseminated disease. While locally advanced tumor in the neck and mediastinum can be treated with surgery either for palliative or curative intent, distant metastases are not often amenable to operative excision. Metastatic MTC has a similarly poor response to radiotherapy and chemotherapy. Viable therapeutic options for distant metastatic disease are still absent. Survival rate after discovery of distant metastasis has been around 25% at 5 years and 10% after 10 years, though this has more recently been improved due to earlier discovery of the malignancy (12, 13). However, new molecular targets have expedited the oncologic research

It consists of two types of tissues, follicular and parafollicular. The follicular tissues are the ones that secrete hormones containing iodine called thyroxine (T4) and triiodothyronine (T3). The parafollicular tissues secrete the hormone called calcitonin. Together these play an important role regulating calcium balance and metabolism. Thyroid hormones regulate

The thyroid which is a butterfly shaped gland situated between your voice box and collarbones and no bigger than your thumb, influences practically every process in your body. It produces hormones that regulate metabolism and energy. The rate in which the brain, heart, liver, and other organs function is influenced by the thyroid gland. Hypothyroidism as characterized by the medical dictionary; is deficient activity of the thyroid gland. Also, called underactive thyroid, hypothyroidism is an endocrine disorder where the thyroid gland does not produce enough thyroid hormones to address the body’s need.

The differentiation of single benign nodule and malignant one is considered an important goal. Early diagnosis of thyroid cancer avoids unneeded surgery in those complaining of benign nodules and decreases both mortality and morbidity rates of the disease (2).