Papillary Squamous Cell Carcinoma

BASEL CELL and SQUAMOUS CELL can often group them selves together and they call this “skin cancer”

Carcinomas- glands, organs and tissues, arise from epithelial cell lining external and internal body surfaces; most common cancer

the American Cancer Society there are benign tumors, which are rare and often develop in

The mandibular tumors arise more frequently in the posterior body and in the horizontal ramus whereas the maxillary tumors occur in the alveolar ridge, the sinus floor and the palate. (2, 5-7) Symptoms usually include painful swelling in the area and loosening of teeth, although paresthesia, nasal obstruction and ophthalmic complications such as proptosis may be noted. The radiographic finding varies from radiopaque , mixed radiopaque - radiolucent or entirely radiolucent lesion with irregular border. Widening of the periodontal ligament space and enlargement of the mandibular canal also widely described as important radiographic features. The radiographic feature of OS are not patogonomonic.(2-4, 6, 8, 9) Thus incisional biopsy and histopathological analysis are essential for the final diagnosis and further treatment. Depending on the relative amounts of osteoid ,cartilage or collagen fibers produced by the tumor, Many pathologists subclassify OSs into the three types: osteoblastic, chondroblastic and fibroblastic (3, 4, 6, 7, 9). This article reports a case of chondroblastic OS of maxilla. The aim of this case was to draw attention to the possibility of diagnosing this tumor based on its clinical and radiographical characteristic before its confirmation by

know as physis, is the area of growing tissue near the end of the long bones in people.

Esophageal carcinoma, the eighth most common cancer in the world, includes squamous cell carcinoma and adenocarcinoma (Sun, Lin, Chen, Liang, &Hsieh, 2015; American Cancer Society, 2015). Squamous cell carcinoma is simply damaged esophageal cells; however, adenocarcinoma occurs when glandular cells replace squamous cells in the esophagus (American Cancer Society, 2015). While squamous cell carcinoma was once the most common form of esophageal carcinoma in the United States, adenocarcinoma has taken its place with speculation placed towards the increase of gastroesophageal reflux disease (GERD) (Baldwin, 2015). These two manifestations of cancer account for approximately 90% of diagnosed esophageal cancers, while the remaining 10% of esophageal

The patient had facial and acral lesions which biopsy confirmed trichilemmomas and acral keratosis. Thyroid and breast sonography showed multiple benign nodules which was

In view of the desmoplasia often surrounding these lesions, the distinction between in situ and invasive papillary carcinoma can be very difficult to make. Therefore, IPC had been divided it into three subgroups which seem to correlate with the prognosis: IPC alone, IPC plus DCIS and IPC with invasion[5]. In this manner, the term “papillary DCIS” would refer to a more diffuse process that involves multiple ducts as opposed to a localized lesion[5].

This finding usually reflects the presence of a marked focal fibrous stromal reaction in the sclerosed hemangiomas and should not be considered a definite marker of malignancy (5, 19).

In the majority of cases the tumour cells have round, oval, or irregularly shaped nuclei, prominent eosinophilic nucleoli and abundant cytoplasm1, thus exhibiting characteristic morphology of anaplastic cells. Less commonly, they have a non-anaplastic appearance thus are pleomorphic or immunoblastic in approximately 20-25% 25, 27. On the periphery of the lesions, reactive lymphocytes are present. Also ulcerating lesions may have a LyP-like histology with a vast inflammatory infiltrate of reactive T-cells, histiocytes, eosinophils, neutrophils and relatively few CD30-positive cells. Thus, in these cases hyperplasia may be seen. In the rare neutrophil-rich pyogenic variant the inflammatory background is very abundant 4,

Notably, skin cancer is known to be an uncontrolled growth of abnormal skin cells (similar to how every cancer functions but differs in types of cells and how it alters DNA sequences), and is mostly triggered by overexposure to ultraviolet light from solar radiations or tanning beds. Hereditary factors, weak immunes systems or others diseases also cause skin cancer which thankfully can be prevented. The three most common skin cancers are basal-cell cancer, squamous-cell cancer and melanoma.

Severe dysplasia, CIN III, encompasses more than two-thirds of the epithelial thickness with carcinoma in situ (CIS) representing full-thickness dysmaturity. While histologically evaluated lesions are characterized using the CIN nomenclature, cytologic smears are classified according to the Bethesda system, which was most recently revised in 2001. Briefly, atypical squamous cells are divided into those of undetermined significance (ASC-US) and those in which a high grade lesion cannot be excluded (ASC-H). Low-grade squamous intraepithelial lesion (LSIL) encompasses cytologic changes consistent with koilocytic atypia or CIN I. High-grade squamous intraepithelial lesion (HSIL) denotes the cytologic findings corresponding to CIN II and CIN III. CIN may be suspected because of an abnormal cytologic

Squamous cell carcinoma is a form of cancer that occurs in the squamous cells, which are located on the surface layer of many organs and is most commonly associated with the epidermis of our skin. However, squamous cells are not only in the tissue that we see on the exterior of the body, but many of the surface tissues on the interior of our body like the oral cavity, lungs, and digestive tract.

Skin papilloma - benign growths caused by the human papilloma virus (HPV). They are more cosmetic than medical problem.

Human Papilloma Virus is a DNA virus that capable of infecting human and productive to infect in keratinocytes of the skin. Some of it also infect mucous membrane. Most of them are subclinical and it causes no physical symptoms. Some of them can cause benign papillomas and it will be cancer. In some of development countries, some tests may do to detect the abnormal cells and it can develop to cancer.